m1 chave Flashcards

1
Q

This theory states that all blood cells are derived from a single progenitor cell called pluripotent stem cell.
a. Unitarian theory
b. Dualistic theory
c. Stem cell theory

A

-Unitarian theory

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2
Q

The renewal or differentiation of HSC’s is determined by the microenvironment in the bone marrow.
a. Dualistic model
b. Instructive model
c. Stochastic model

A

-instructive model

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3
Q

What objective is used to view metastatic tumor cells or lymphoblasts?
a. HPO
b. OIO
c. LPO

A

-LPO

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4
Q

The center of leukopoiesis
a. Reticular adventitial cells
b. Fat cells
c. Bone marrow

A

-Reticular adventitial cells

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5
Q

Which is the preferred site of bone marrow collection if the patient can only lie supine.
a. Sternum
b. Posterior superior iliac crest of the pelvis
c. Anterior superior iliac crest of the pelvis

A

-Anterior superior iliac crest of the pelvis

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6
Q

Precursor cell of erythrocyte
a. Histiocyte
b. Reticular cells
c. Normoblast

A

-Normoblast

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7
Q

A profound defect in the maturation of all formed elements is known as _____
a. Homoplastic hematopoiesis
b. Heteroplastic hematopoiesis
c. Dyspoiesis

A

c. Dyspoiesis

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8
Q

Bone Marrow aspirate can be used for histopathology if properly preserved in _____.
a. EDTA
b. 10% formalin
c. 22% albumin

A

-10% formalin

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9
Q

It is the standard strain used for core biopsy specimens.
a. H&E stain
b. Prussian blue
c. Wright’s stain

A

a. H&E stain

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10
Q

It is a group of specific glycoproteins that regulates the proliferation, differentiation and maturation of hematopoietic precursor cells.
a. HLA-DR
b. HSC’s
c. Cytokines

A

c. Cytokines

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11
Q

Major site of T cell production
a. Liver
b. Thymus
c. Kidney
d. Spleen

A

-Thymus

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12
Q

It is the largest hematopoietic cell found in a normal bone marrow aspirate
a. Megakaryocyte
b. Myeloblast
c. Osteoblast

A

a. Megakaryocyte

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13
Q

This theory states that all blood cells are derived from a single progenitor cell called pluripotent stem cell
a. Unitarian theory
b. Dualistic theory
c. Stem cell theory

A

-Unitarian theory

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14
Q

This theory states that each of the blood cell lineages is derived from its own stem cell
a. Monophyletic Theory
b. Dualistic Theory
c. Unitarian Theory

A

-Dualistic Theory

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15
Q

Bone marrow can produce ____ of cells/kg of body weight each day.a
a. 6 billion
b. 2.5 billion
c. 1.5 billion

A

-6 billion

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16
Q

It is known as the center of Erythropoiesis
a. Macrophage
b. Bone Marrow
c. Mast Cells

A

a. Macrophage

17
Q

Bone marrow aspirate should be examined under LPO to assess all of the following excep,
a. Observe fat to marrow ratio
b. Computation of M:E ratio
c. Estimation of Megakaryocytes
d. Search for tumor cells in cluster

A

b. Computation of M:E ratio

18
Q

_____ is added to the solution to reduce the occurrence of basket or smudge cells to the bone marrow specimens.
a. 10% formalin
b. 22% Albumin
c. EDTA

A

b. 22% Albumin

19
Q

Which of the following stromal cells in the bone marrow secretes cytokines and is also involved in the regulation of marrow volume?
a. Mast Cells
b. Endothelial Cells
c. Adipocytes

A

c. Adipocytes

20
Q

Which of the following developmental period of hematopoiesis occurs at the 19th day after fertilization?
a. Mesenchymal Period
b. Hepatic Period
c. Myeloid Period

A

-Mesenchymal Period

21
Q

Which cells are produced by the kidney and spleen during the Hepatic period?
a. Erythroblast
b. T cell
c. B cell

A

-B cell

22
Q

What is the normal Myeloid to Erythroid (M:E) ratio range in normal range adult?
a. 5.1:1-6.2:1
b. 1.5:1-3.3:1
c. 2.1:1-3.5:1

A

-1.5:1-3.3:1

23
Q

It is the bone forming cells
a. Osteoblast
b. Osteoclast
c. Mast Cells

A

-Osteoblast

24
Q

If the bone marrow has few or no hematopoietic cells it is known as ____
a. Aplastic
b. Hypoplastic
c. Dry Tap

A

-Aplastic

25
Q

M:E ratio is increased in the following conditions EXCEPT
a. Infection
b. Normoblastic hyperplasia
c. CMLa
d. Erythroid Hypoplasia

A

-Normoblastic hyperplasia

26
Q

It is a random process of Hematopoiesis
a. Instructive Model
b. Stochastic Model
c. Unitarian Model

A

b. Stochastic Model