M2 BABESIA Flashcards

1
Q

Resemble plasmodium with no malarial pigments

A

Babesia microti

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2
Q

Causes tickborne malaria like illness on domestic and wild animals

A

Babesia microti

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3
Q

Causes opportunistic infection on humans

A

Babesia microti

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4
Q

B. microti is named after

A

Babes

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5
Q

In 1888, described the intraerythrocytic parasite in the blood of cattle and ship

A

Babes

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6
Q

First arthropod-borne disease

A

B.microti

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7
Q

Definitive host of B. microti

A

Ixoxid tick

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8
Q

Intermidiate host of B. microti

A

Mammals

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9
Q

B. microti can be transmitted through ___ & ___

A

Blood transfusion and placentally

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10
Q

Infective form of B. microti in human

A

Sporozoite

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11
Q

MOT: bite of ___ stage of ixoxid ticks

A

Nymphal stage

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12
Q

Size of tropozoite in B. microti

A

2-5 um

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13
Q

Trophozoite of B. microti found in

A

Red cells

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14
Q

B. microti, Shape may be pyriform, ameboid, spindle like

A

Trophozoite

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15
Q

B. microti, spherical or oval

A

Merozoite

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16
Q

2 host of B. microti

A
  1. White footed rodent
  2. Ixodes tick
17
Q

Sporozoite undergo asexual reproduction called

A

Budding

18
Q

Infected ticks introduces ___ into the human host

A

Sporozoite

19
Q

Vertical heriditary transmission. Has been documented for large babesia spp but not for small babesia spp like B.microti

A

Transovarial transmission

20
Q

Dead end host of B.microti

A

Human

21
Q

Primarily responsible for many clinical manifestation

A

Hemolysis of infected erythrocyte

22
Q

Illness develops how many weeks after tick bites . B.microti

A

1-6 weeks

23
Q

B.microti fever exceeds

A

38° - 40.6°

24
Q

Sever babesiosis is associated with parasitemia levels of more than ___ infected RBC’s

A

4%

25
Q

Fatality rate B.microti

A

5%

26
Q

Fatality rate immunocompromised. B.microti

A

20%

27
Q

Complications of acute babesiosis

A
  1. Acute renal failure
  2. Disseminated intravascular coagulation
  3. Acute respiratory distress syndrome
  4. Congested cardiac failure
28
Q

Stain B.microti

A

Giemsa and Leishman

29
Q

Distinguished features of B.microti

A

Presence of tetrads

30
Q

Maltose crosses

A

Tetrads

31
Q

Serology of B.microti, useful in conforming disease

A

Indirect immunofluroscent antibody (IFA)

32
Q

___ count is elevated. B.microti

A

Reticulocyte

33
Q

___ is common. B.microti

A

Thrombocytopenia

34
Q

___ count may be normal or slightly decreases

A

WBC

35
Q

B.microti. liver function test

A

Serum glutamic pyruvate transaminase (SGPT)

36
Q

Application of bug repellents like DEET ?

A

N,N-diethyl-meta-toluamide

37
Q

In renal complicarions, ___ are found

A

Bloor urea nitrogen and serum creatinine