MAB 1 Flashcards
What are enzymes
Organic catalysts
Protein molecules that are produced within living cells and have a specific shape
Role of enzymes
Control all chemical processes of living things. They enable reactions to occur. Used over and over and remain unchanged.
An efficient rate of metabolism is necessary for life processes to continue
Explain the lock and key model
An enzyme fits together with its substrate molecule on its active site. It’s active site is very specific meaning only one compound can react with a particular enzyme.
Why use “lock and key”
The key has a specific shape for the lock. Like the substrate has a specific shape for the active site.
The active site = lock
Substrate = key
Induced fit model?
- proteins are not rigid
The active site is more flexible and is changed by the substrate binding to it.
Types of metabolism and explain
Anabolic - reactions that involve building up large organic molecules form simpler molecules
Catabolic- reactions that involve breaking down complex organic compounds to simpler ones. (Amylase in saliva)
How does temperature affect enzyme activity
As temperature rises, the rate increases because molecules move faster. However, beyond the optimum temperature (37), the active site begins to be distorted. The substrate no longer fits the active site and so reaction slows down. At extremes, the enzyme will denature
How does pH affect enzyme activity
The optimum pH for enzymes is 7. The enzyme works best as at the optimum, it is ideal for attracting the substrate. At any pH higher or lower than optimum, reaction rate declines as the substrate no longer fits perfectly and at extremes on both sides, enzyme will denature
How does substrate concentration after enzymes
The rate of reaction will go up until a cartoon point when the enzymes are saturated with substrate and can no longer work any faster. If you add more enzymes then the same thing would happen again
Identify pH as a way of describing the acidity of a substance
PH is a way of describing the acidity of a substance. The pH scale measures alkalinity/acidity
Under 7 = acidic
Over 7 = alkaline
Measure pH using a probe/data logger to increase accuracy and universal indicator
What’s metabolism?
All chemical reactions occurring within a living organism & are controlled by enzymes
Why is the maintenance of a constant internal environment important for optimal metabolic efficiency
Enzymes control all the metabolic processes in the body. For optimum metabolic efficiency, the reaction in cells must be occurring at the optimum rate. Enzymes can only act within a limited temperature and pH range. If enzymes are not working at the optimum range then reactions cannot be maintained at a stable rate then metabolic efficiency cannot be maintained
What is homeostasis
The process where an organism maintains a relatively stable internal environment despite external conditions
How can a stable internal environment be maintained within an organism
Through adaptation:
Structural - physical characteristics ( body size, limbs )
Physiological - organisms function. The way an animal operates ( sweating, production of enzymes)
Behavioural - how an organism acts in response (seeking shelter)
What stages that homeostasis consist of
- Detecting change
2. Counteracting change
What is detecting change?
Sensory cells / receptors present within the body detect change in the temperature and chemical composition of the body.
What is counteracting change
Effector organs such as muscles or glands then work to reverse the change. A response that successfully reverses the change will return the body to homeostasis
What are the parts of a homeostasis system
Receptors
Control centre
Effectors
What is the receptor and how does it work
Monitors changes in the internal and external environment and initiates a response to them. They do this by sending a message to the control centre
What is the control centre and what does it do
Is programmed to maintain the set value, analyses the message from receptors and determines the appropriate response. The control centre causes a response to be sent out via an effector that restores the set value
What is the effector
They bring out the responses to stimuli
Eg muscles, glands
What is the change in the environment called
Stimulus
What is the mechanism that brings about the homeostatic change
Negative feedback mechanism
What does the negative feedback mechanism do
During the second stage (response), if a set value deviates then negative feedback instructs the system to restore the correct value, meaning negative feedback counteracts the change