macrolides Flashcards

1
Q

macrolide

A

azithromycin
clarithromycin
erythromycin

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2
Q

macrolide coverage

A

gram positive (staph and strep)
respiratory gram negative (h. flu, catarrahalis, neisseria)
atypical (chlamydia, legionella, pneumonia)

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3
Q

macrolide use

A

respiratory track infections, alternative to PCN allergy, mycobacterium

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4
Q

ADR macrolide

A

QT prolongation, GI intolerance, anorexia, rash, elevated LFTs, jaundice

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5
Q

DDI for macrolide

A

3A4 substrate and inhibitor (erythro> clari)

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6
Q

Macrolide’s time-dependent or concentration dependent? Bacteriostatic or -cidal?

A

time-dependent and static

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