Maine Question Bank Flashcards

(43 cards)

1
Q

What tumors frequently metastasize to lymph nodes?

A

“SCARE”
1. synovial sarcoma
2. clear cell sarcoma
3. angiosarcoma
4. rhabdomyosarcoma
5. epithelioid sarcoma

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2
Q

anterolateral bundle of the PCL is tight in _______

A

mid flexion

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3
Q

posteromedial bundle of the pcl is tight in _____

A

both middle and high flexion

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4
Q

what is at risk with bicortical C1 lateral mass screws?

A

ICA

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5
Q

what is at risk with C1 pars screws?

A

vertebral a

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6
Q

Anteromedial bundle of the ACL is tight in _______

A

the anteromedial bundle of the ACL is tight in both flexion AND extension

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7
Q

Posterolateral Bundle of the ACL is tight in ________

A

posterolateral bundle of the ACL is TIGHT in extension and LOOSE in flexion

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8
Q

indications for static spacer in revision tka rather than dynamic spacer

A

uncontrolled infections
ligamentous laxity
extensor mechanism compromise/disruption
poor soft-tissue coverage or severe bone loss.

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9
Q

what size particles stimulate osteolysis

A

sub-micron - that is 0.1 - 1um diameter particles

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10
Q

what factors increase a patients risk of MRSA colonization

A

male
younger age
african american > caucasian

urban environments do not influence rates of colonization

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11
Q

how does biofilm allow the bacteria to evade antibiotics?

A

protective scaffolding formation

Following initial adherence and colonization, bacteria are thought to form a complex matrix of an extracellular polymetric substance, serving as a protective scaffold in which they can survive despite the competence of the host’s immune system or the presence of antimicrobial agents

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12
Q

nutritional markers for wound healing after arthroplasty

A
  • transferrin <200
  • neutrophil count <1500
  • albumin <3.5g/ml
  • zinc <95
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13
Q

what are the most common complications of tka (in order of frequency of occurrence)?

A

periprosthetic joint infection
aseptic loosening
instability
polyethylene wear
arthrofibrosis
malalignment

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14
Q

allograft should be added to distal biceps repair if the native tendon cannot reach the tuberosity in what degree of flexion?

A

90 degrees

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15
Q

what is the primary restraint to valgus stress at the knee in full extension?

A

posteromedial corner

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16
Q

what is the primary restraint to valgus stress at the knee in 30degrees flexion

A

superficial MCL

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17
Q

most common iatrogenic nerve injury during latarjet?

A

Axillary then musculocutaneous

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18
Q

what is an absolute contraindication to lumbar disc replaccement?

A

osteoporosis - need to get a DEXA scan prior to surgery

19
Q

where is the physis affected in gymnasts wrist?

A

Zone of provisional calcification
- repeated loading decreases vascularity -> diminished calcification

*** this is different from a salter harris fracture which occurs at the zone of hypertrophy

20
Q

What proteinaceous compound binds to hyaluronic acid to function as an effective boundary molecular layer in articular cartilage?

A

Hyaluronic acid binds to LUBRICIN
lubricin acts to reduce the coefficient of friction in the joint

21
Q

what mechanism is associated with metal on metal hips in pseudotumor formation

A

edge loading and associated loss of fluid film lubrication
while it is a lymphocyte driven reaction, it is not actually lymphocytes reacting to nickel, cobalt, or chrome molecules

22
Q

what human bone disease would result from loss of OPG protein?

A

osteoporosis
- OPG INHIBITS osteoclast activation (osteoclasts resorb bone)
- no opg -> no turning off osteoclasts -> unchecked bony resorption -> osteoporosis

23
Q

what is the most common soft tissue sarcoma of the foot?

A

synovial sarcoma
young adult males 15-40yo
t(x,18) -> SYT-SSX1, or SYT-SSX2 gene

24
Q

what orthopedic tumor are ring chromosomes associated with?

A

parosteal osteosarcoma

25
what tissue factor is associated with muscle fibrosis during healing?
TGFB1
26
hemophilia A - genetics and functional defect?
X-linked disorder Factor VIII deficiency recurrent spontaneous hemarthroses
27
what is the mechanism of action of calcitonin
reduces serum calcium concentration by directly interfering with osteoclast maturation via receptors - inhibits phosphate reabsorption and decreses calcium reabsorption in the kidneys
28
when does adhesive wear most commonly occur
well placed THA
29
when does abrasive wear occur
1. damages surface - eg a femoral head scratched on implantation 2. third body wear - eg cement in tka
30
when does delamination occur?
with oxidized poly (eg irradiated in air) tkas in high contact stresses
31
Characteristics of healed ligament one year later
1. increase in proportion of type III colagen early (returns to normal at 1 yer) 2. increased absolute number of collagen fibers 3. decreased number of collagen cross links (45% of predicted values) 4. decrease in the mass and diameter of the collagen fibers
32
perichondral ring of lacroiz
fibrocartilaginous ring surrounding the physis that provides 50% of resistance to shear stress
33
how does physeal arrest occur following physeal fracture?
vascular invasion across the physis
34
how do thiazolidenedione antihyperglycemics increase the risk of fracture?
suppress osteoblastic transcription factors they activate peroxisome proliferator activated receptor gamma (PPARy)
35
extrinsic tendon healing
occurs in synovial shathed tendons faster healing increased tendon scarring
36
intrinsic tendon healing
relies on proliferation and migration of cells within an injured tendon slower healing no adhesion formation
37
antibiotic spacer peak drug elution occurs when? how long can concentrations remain bacteriocidal?
24 hours; 4 months
38
when do bmp concentrations peak during masquelet technique? when do they return to baseline?
4 weeks - peak 6 months - return to baseline
39
A lateral wall thickness less than what threshold has been associated with secondary lateral wall fracture during the treatment of intertrochanteric femur fractures using a compression hip screw?
20.5mm
40
outcomes of surgically managed elderly distal radius fracture at 1 year
- surgically treated patients have better wrist ROM at 6 months, but at one year only grip strength has been shown to be significantly better
41
most important ligament in the lis franc complex?
oblique interosseous ligament (aka the lis franc ligament)
42
what are the three ligaments of the lis franc complex and which is the most important?
1. oblique interosseous ligament (most important) 2. plantar oblique ligament 3. dorsal oblique ligament (dorsal ligaments are the weakest)
43
Charcot marie tooth genetic mutation
Autosomal DOminant duplication of the peripheral myelin protein (PMP) on chromosome 17