Major Adjustments to Circulatory System During Exercise. Flashcards

(29 cards)

1
Q

Increase Cardiac Output (Q) Formula

A

(Q = HR * SV); Typical values at rest and during exercise depend on training state and gender

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2
Q

Heart Rate (HR)

A

Number of beats per minute

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3
Q

Stroke Volume (SV)

A

Amount of blood ejected in each beat

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4
Q

Parasympathetic Nervous System

A

Via vagus nerve; Slows HR by inhibiting SA and AV Node

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5
Q

Sympathetic Nervous System

A

Via cardiac accelerator nerves; Increases HR by stimulating SA and AV node

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6
Q

Low resting HR due to…

A

Parasympathetic Tone

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7
Q

Increase in HR at onset of exercise

A

1st parasympathetic withdrawal (up to ~100 bpm), 2nd increased SNS stimulation

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8
Q

Expected Values for Untrained Male at Rest

A

72 b/min x 70 ml/beat = 5.00

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9
Q

Expected Values for Untrained Female at Rest

A

75 b/min x 60 ml/beat = 4.50

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10
Q

Expected Values for Trained Male at Rest

A

50 b/min x 100 ml/beat = 5.00

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11
Q

Expected Values for Trained Female at Rest

A

55 b/min x 80 ml/beat = 4.40

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12
Q

Expected Values for Untrained Male at Max Exercise

A

200 b/min x 110 ml/beat = 22.0

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13
Q

Expected Values for Untrained Female at Max Exercise

A

200 b/min x 90 ml/beat = 18.0

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14
Q

Expected Values for Trained Male at Max Exercise

A

190 b/min x 180 ml/beat = 34.2

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15
Q

Expected Values for Trained Female at Max Exercise

A

190 b/min x 125 ml/min = 23.8

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16
Q

End-Diastolic Volume (EDV)

A

Volume of blood in the ventricles at the end of diastolic (“Preload”)

17
Q

Average Aortic Blood Pressure

A

Pressure the heart must overcome to eject blood (“Afterload”)

18
Q

Strength of Ventricular contraction (contractility) is enhanced by

A

Circulating epinephrine and norepinephrine, Direct sympathetic stimulation of heart

19
Q

SV is influenced by:

A

Frank Starling Mechanism, Catecholamines

20
Q

Frank Starling Mechanism

A

(Only beneficial to 60% Max exercise) Greater EDV results in more forceful contraction due to stretch of ventricles (Length/Tension Relationship) and is dependent on venous return

21
Q

Venous return is influenced by:

A

1) Venoconstriction (via SNS), (2) Skeletal Muscle Pump (Skeletal muscle cx force blood back toward the heart, One-way valves in veins prevent backflow of blood), (3) Respiratory Pump (Changes in thoracic pressure pull blood toward heart)

22
Q

Catecholamines

A

influence stroke volume by increasing cardiac contractility by increasing the amount of calcium available to the myocardial cell; specifically increase the entry of extracellular calcium into the cardiac muscle fiber which increases cross bridge activation and force production

23
Q

Where does majority of blood goes at rest?

A

15-20% of cardiac output to muscle

24
Q

Where does majority of blood goes during exercise?

A

Increases to 80-85% during maximal exercise; Decreased blood flow to less active organs (Liver, Kidneys, GI Tract), Redistribution depends on metabolic rate (Exercise Intensity)

25
Metabolic need:
Autoregulation refers to intrinsic control of blood flow by increases in local metabolites (e.g., nitric oxide, prostaglandins, ATP, adenosine, and endothelium-derived hyperpolarization factors). These factors work together to promote vasodilation to increase blood flow to the working muscles.
26
The exercise-induced increase in local factors result in...
Increased vasodilation of arterioles/small arteries and promote increased blood flow to the contracting muscle in order to match the metabolic demand.
27
Autoregulation
Blood flow increased to meet metabolic demands of tissue due to changes in O2 tension, CO2 tension, Nitric Oxide, Potassium, Adenosine, and pH
28
Cardiovascular Control Center
Regulates vascular resistance in skeletal muscle decreases during exercise, vascular resistance to flow in the visceral organs and other inactivity tissue increases.
29
As a result of the increase in visceral vasoconstriction during exercise (resistance increases):
blood flow to the viscera can decrease to only 20% to 30% of resting values