Male Cancer

Question 1

Testicular lymphatics drain to which two nodes?

Answer 1

1. Lumbar
2. Para-aortic
   (NOT INGUINAL)

Question 2

The Prostate lymph goes to the ____ nodes

Answer 2

Hypogastric

Question 3

Vast majority of early prostate cancers are ____ receptor dependent

Answer 3

Androgen

Question 4

_____ of the prostate is the most common form of cancer in men, especially OLDER men

Answer 4

Adenocarcinoma

Question 5

Yolk Sac Tumors are the most common testi tumor in _____

Answer 5

Infants

Question 6

Uniquely, Testicular torsion presents as _____ pain and a loss of _____ relfex in children

Answer 6

• Abdominal

- Cremasteric

Question 7

The Testis lymph goes to the _____ nodes

Answer 7

Paraaortic

Question 8

Prostate Cancer histo usually includes ____ (number) of cell layers along with ____ nuclei

Answer 8

• Single

- Large

Question 9

Considering that the Prostate Stromal cells utilize 5-a-Reductase to make DHT and continue Stromal Proliferation; a drug such as _____ would be great to inhibit 5-a-Reductase or ALPHA-1A BLOCKERS TO RELAX THE MUSCLES

Answer 9

Finasteride

Question 10

Teratomas are benign for ______ and malignant for _____

Answer 10

• Pre-puberty

- Post-Puberty

Question 11

Buzz-Word for testicular Torsion

Answer 11

“Bell Clapper Deformity”

Question 12

The Penis lymph goes to the _____ nodes

Answer 12

Inguinal

Question 13

In regards to Germ Cell Tumors, Embryonal Carcinoma Tumors are more AGGRESSIVE than Seminoma and may have Serum _____(yolk) and _____ (chorio) elevation

Answer 13

• a-AFP

- HCG

Question 14

95% of testicular cancers are germ cell tumors which are wither _____ that resemble germ cells or _________ that are undifferentiated

Answer 14

• Seminoma

- Non-Seminoma

Question 15

Usually from age ____ to _____ Testicular tumor is most common

Answer 15

15-35

Question 16

Castration leads to _____ of the prostate

Answer 16

Atrophy

Question 17

A testicular hydrocele is when fluid builds up in the ___ ___

Answer 17

tunica vaginalis

Question 18

Prostate cancers typically occur in the _____ Zone of the prostate

Answer 18

Peripheral

Question 19

Key Yolk Sac Histo Finding?

Answer 19

Schiller Duval Bodies

looks like glomeruli

Question 20

Most common testicular mass in male >50 is actually a ______

Answer 20

DLBC Lymphoma

Question 21

Since choriocarcinoma makes a lot of HcG, what other hormone receptors can be activated?

Answer 21

• Thyroid (hyper)

- FSH/LH (Gynecomastia)

Question 22

Seminomas almost never occur in _____ and have excellent prognosis

Answer 22

Infants

Question 23

Although embryonal carcinoma might have elevated Serum AFP the most common Testi tumor in infants, _____ ____ Tumors, will 100% have elevated AFP (100’s-1000’s ng/mL).

Answer 23

Yolk Sac

Question 24

To treat testicular neoplasms NEVER do what 2 things?

Answer 24

• Biopsy
• Cut into scrotum
  (No trans-scrotal orchiectomy or biopsy)

Question 25

Seminomas never hit infants and can contain synctiotrophoblasts that produce _____

Answer 25

HCG

Question 26

What does prostate cancer do to the bones?

Answer 26

BUILDS with osteoblasts

Question 27

BPH typically occurs in the _____ Zone of the prostate

Answer 27

Transition

Question 28

How does Finasteride treat BPH?

Answer 28

Inhibits 5-a-Reductase | Inhibits stromal proliiferation

Question 29

Priapism

Answer 29

Erection for more than 4 hrs

Question 30

2 Kinds of Non-Seminoma Testi Tumors

Answer 30

1. Teratoma | 2. Yolk sac (embryonal carcinoma or choriocarcinoma)

Question 31

Key Choriocarcinoma Lab finding?

Answer 31

Elevated hCG >100,00 mIU/mL

Question 32

Isochromosome of the short arm of chromosome 12 is PATHOGNOMONIC for _____ tumors

Answer 32

Testicular

Question 33

In the descent of the testis the coelomic cavity evaginates into scrotal swelling and forms the pocket known as _____ ____, which should obliterate

Answer 33

Processus Vaginalis

Question 34

How to treat testicular neoplasm surgically?

Answer 34

- Remove testis and spermatic cord form inguinal ring | Radical Inguinal Orchiectomy

Question 35

2 Hormonal treatments to prostate cancer

Answer 35

1. Continuous GnRH analog (leuoprolide) | 2. AR atnagonists (flutamine)