Male Genital System 2 Flashcards
(16 cards)
Most common neoplasm of the testes?
Germ Cell Tumor
Most common germ cell tumor?
Seminomas
Seminomas?
Most common type of germ cell tumor to occur in “pure” form
- Grossly appears homogeneously
- Not typically necrotic or hemorrhagic
Seminomas microscopically?
Characteristic distinct cell membrane and clear cytoplasm giving a “fried egg” appearance to the cells
Can seminomas produce hCG?
Yes - about 15% of them do –> these are mixed germ cell tumors
Embryonal carcinoma?
More commonly a mixed germ cell tumor
More aggressive than a seminoma
Grossly are necrotic or hemorrhagic
Microscopically shows sheets, alveoli, tubules, or papillary formations –> anaplastic looking cells (undifferentiated)
Yolk Sac Tumor?
Almost exclusively a tumor of infants and children up to 3 years of age
If in adults, mixed with other germ cell tumor patterns
Produces Alpha fetoprotein (AFP) - can be seen in immunohistochemical stain
Choriocarcinoma?
Mostly mixed with other germ cell tumors
Highly Aggressive
Mimics the histology of the placenta
Produces hCG
Very vascular –> metastasis bleed easily
Use stain for hCG producing syncitiotrophoblast type cells
Prostate?
A retroperitoneal gland which encircles the neck of the bladder
What is the prostate composed of?
Glandular cells within a supporting stroma; the glands produce secretions which constitute seminal fluid
Where does prostate hyperplasia typically occur?
Transitional and periurethral zones –> urinary flow problems
Where does prostate carcinoma occur?
In the peripheral zone –> no urinary flow problems
Prostate hyperplasia?
Nodular hyperplasia –> androgen driven and results from hyperplasia (not hypertrophy) of prostatic glands and stroma
Most common carcinoma in men?
Prostate
Describe a prostate carcinoma?
Pale yellow and stands out from rest of the gland –> often palpated before being seen
Common metastasizes of prostate carcinoma?
Bone - osteoblastic
