Male Reproduction Introduction Flashcards

(50 cards)

1
Q

Basic Male Anatomy

A

Seminiferous tubule, Rete testis, Efferent dustules, Epididymis, Vas deferens/Ductus deferens
Spermatic cord, Abdominal activity, Prostatic urethra, Seminal vesicles, Penis

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2
Q

A capsule of Dense CT

A

Tunica Albuginea

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3
Q

split testis into>200 lobules

A

Septa

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4
Q

Circular structures

A

Intertitial cells and Seminiferous tubules

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5
Q

Steroid-secreting cells

A

Leydig cells

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6
Q

Function of Leydig cells

A

Secrete testosterone

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7
Q

Primary male hormone responsible for: sex differentiation producing male sex characteristics
spermatogenesis
fertility

A

Testosterone

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8
Q

HUGE amount of SER (eosinophilic)

A

steroid-secreting cells

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9
Q

In adults, testoterone secretion is crucial for

A

Spermatogenesis and secondary sex characteristics

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10
Q

Stratified epithelium with Sertoli cells

where the maturation of sperm (spermatogenesis) occurs with sertoli cells

A

Seminiferous tubules

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11
Q

Near the base of tubule large, lightly stained, triangular nuclei

A

Sertoli cell

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12
Q

Sertoli cell functions

A

provide physical support and organization for developing sperm linked together-tight junction-ZONULA OCCLUDENS-BTB (BLOOD TESTIS BARRIER)

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13
Q

blood testis barrier funx

A

Isolates haploid antigenic cells from the systemic immune system

Sertoli cells secrete ANDROGEN BINDING PROTEIN (ABP)

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14
Q

requires high concentrations of local testosterone

A

Spermatogenesis

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15
Q

Spermatogenesis

A

Maturation: begins near the Basal lamina-moves toward the ST Lumen

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16
Q

Exist between the Basal lamina of ST and Sertoli cells located OUTSIDE the BTB

A

Spermatogonia

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17
Q

As they mature, the B spermatogonia will undergo mitosis and become

A

Primary spermatocytes

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18
Q

Which exists INSIDE the BTB; between the Seroli cells and ST Lumen

Undergoing meiosis

stringy appearance due to chromosomes lining up

A

primary spermatocytes

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19
Q

Primary spermatocytes are undergoing meiosis to become

A

Haploid germ cells aka Spermatids

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20
Q

As they Mature: they go through many morphologic changes during spermiogenesis

A

Spermatids

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21
Q

Spermatids four phases

A

Golgi phase, Cap phase, Acrosome phase, Maturation phase

22
Q

Maturation of spermatids

A

physically connected to seroli cell membranes via special junctions

23
Q

Final phase of spermatid

A

spermatids released from SC into ST lumen as Mature sperm cells aka spermatozoa

24
Q

Non-motile
Travel through ST in Sertoli cell fluid towards the epididymis

25
dense CT of mediastinum
ST
26
Dense CT of Mediastinum Irregular spaces lined with cuboidal epithelium lead to excurrent ducts between ST and epididymis
Rete testis
27
Extratesticular;located between rete testis and epididymis Saw-tooth epithelium of ciliated columnar and non ciliated cuboidal
Efferent ductules
28
Functions of efferent ductules
Absorbs fluids secreted by sertoli cells "Alternating groups" border
29
Numerous section of epididymis- circular structures throughout
Epididymus duct, epididymis duct epithelium, epithelium with stereocilia
30
More even border than efferent ductules
epididymis duct
31
Tall pseudostratified columnar epithelium
epididymis duct epithelium
32
long modified microvilli contain core of actin filaments
Epithelium with stereocilia
33
Epithelium with stereocilia function
absorption
34
Clumps in the lumen – which have mature in the epididymis gaining motility and ability to fertilize an oocyte Smooth muscle surrounding the lining epithelium; undergoes rhythmic peristaltic construction that moves the sperm along the duct
Spermatozoa
35
stores majority of spermatozoa in adult males; VIABLE FOR WEEKS. But once it enters the vagina they can only survive for 3-4 days.
epididymis
36
The direct continuation of epididymis
Vas deferens
37
firm structure of vas deferens
I. thick coat of smooth muscle (blue line) – inner longitudinal layer (green), middle circular layer (red), outer longitudinal layer (black) II. Mucosa appears folded (artifact of fixation) – due to contraction of thick muscular wall III. Vas deferens epithelium: Pseudostratified columnar epithelium with stereocilia
38
Accessory gland with irregular lumen Highly folded mucosa = A defining characteristic of Seminal vesicle Note: larger in younger males with high androgen levels
Seminal vesicle
39
SV Mucosa
Columnar/Cuboidal Epithelium and Thin Lamina Propria
40
Seminal vesicle FUNCTIONS
Secretes seminal fluid; FRUCTOSE and CITRATE-RICH Sperm’s main nutrient source Note: prostate and bulbourethral gland also secretes seminal fluids
41
Aged SV: mucosal layer ATROPHIED Due to lower systemic androgen levels Atrophy decrease in size – cell, organ, or other tissue
Seminal vesicle (aged)
42
Largest male accessory sex gland Secrete alkaline fluid (PH 7.3) for seminal fluid Prostate glandular epithelium: Simple cuboidal/columnar epithelium Prostatic secretions contents: PSA Prostatic Acid Phosphatase Fibrinolysin Citric Acid
Prostate gland
43
Precipitated prostate secretions in prostatic alveoli Appear as circular structures in the secretory alveoli Distinguishing feature of the prostate
Prostatic concretions
44
A section of the prostate where the urethra begins Urethra– crescent-shaped structure Vas deferens Seminal vesicles prostate
Prostatic urethra
45
Urothelium/transitional epithelium – umbrella / dome-shaped cells
Prostatic urethra
46
Structure of Penis
Corpora cavernosa (red) – dorsal side of the penis; bilateral Corpus spongiosum (blue) with Urethra (green) Dense fibroelastic tissue = tunica albuginea. (yellow) = surrounds all three structures
47
Filled with irregular venous spaces lined with vascular endothelium Venous rbcs separated by: Trabeculla of Fibromuscular Connective Tx
Corpus cavernosum
48
Helicine arteries (black arrow) : coiled with flaccid penis and extended with erect penis Oddly shaped with thick walls
Penis
49
helicine arteries dilate – blood fills the venous spaces of cavernosum and spongiosum
Erection
50
Muscles compress veins – decreases the venous return – allowing the erection to be maintained.
The pressure of erect penis, Ischiocavernosus and bulbospongiosus