malignancy translocations and inversions Flashcards Preview

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Flashcards in malignancy translocations and inversions Deck (11)
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1
Q

t(15,17)

A

PML-RARA

APL

2
Q

t(8,21)

A

RUNX-RUNX1T1

AML

3
Q

inv(16)

A

CBFB-MYH11

AML

4
Q

t(v,11q23)

A

x-MLL

ALL

5
Q

t(12,21)

A

TEL-AML1

ALL

6
Q

t(9,22)

A

BCR-ABL1
CML
also, ALL

7
Q

t(11,14)

A

cyclin D1-IgH

Mantle Cell lymphoma

8
Q

t(8,14)

A

MYC-IgH

Burkitt’s

9
Q

t(8,2)

A

MYC-kappa

Burkitt’s

10
Q

t(8,22)

A

MYC-lambda

Burkitt’s

11
Q

t(14,18)

A

BCL2-IgH promoter
follicular lymphoma
diffuse large B-cell lymphoma