Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 3 Gastroenterology & Surgery Block > Malnutrition > Flashcards

Malnutrition Flashcards

1
Q

What is coeliac disease

A

Intolerance to gluten

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the pathology behind coeliac disease

A

Antibodies are made in response to gluten that attack the epithelial cells of the intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What antibodies are involved in coeliac disease

A

Anti-tissue transglutamate (anti-TTG) and anti-endomysial (anti-EMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where is most of the inflammation found in coeliac disease

A

Small bowel, jejunum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is dermatitis herpetiformis

A

Rash on belly, coeliac related

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Failure to thrive in young children, diarrhoea, fatigue, mouth ulcers and weight loss indicate what disease

A

Coeliac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is shown on an endoscopy of a patient with coeliac disease

A

Villous atrophy, crypt hypertrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Villous atrophy causes what

A

Malabsorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tx for coeliac disease

A

Life long Gluten free diet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Gastrointestinal symptoms for coeliac

A

Bloating, flatulance, steatorrhea, vomiting and constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

General features of coeliac disease (4)

A

Delayed period, clubbing, short stature, oedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Extra intestinal symptoms for coeliac (7)

A

Peripheral neuropathy, night blindness (vit A def.), hypertransaminasemia, thrombocytosis, osteomalacia/osteoporosis, infertility, poor education

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Definite associations for coeliac (7)

A

Hyposplenism, dermatitis herpetiformis (extensor surfaces), IgA deficiency, autoimmune thyroid disease, sjorgrens syndrome, type 1 diabetes, microscopic colitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IgA deficiency causes increased risk of?

A

Chest infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what chromosomal abnormality is related to coeliac disease

A

Downs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Refractory sprue?

A

5-10% people dont get better with gluten free diet

17
Q

What cancer is related to non-compliant coeliac disease

A

Enteropathy-associated T cell lymphoma

18
Q

Which genes are related to coeliac

A

HLA-DQ8 and HLA-DQ2

19
Q

What does an endoscopy for coeliac disease look like?

A

Flattened villi, smooth to look and drier

20
Q

What scans do you give someone with coeliac

A

DEXA

21
Q

How to treat resistant coeliac

A

Steroids, other immunosuppressants (azathioprine)

22
Q

Prognosis for coeliac

A

70% improve within 2 weeks

23
Q

Differential diagnoses for coeliac

A

Lactose intolerance, IBS, IBD

24
Q

Risk for coeliac disease in first degree relative?

A

10-15%

25
Q

What 3 flags should you check for coeliac

A

IBS, iron deficiency anaemia, chronic diarrhoea

Year 3 Gastroenterology & Surgery Block (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions