Maternal Medicine Flashcards
(9 cards)
Enzyme inducing antiepileptics
Carbamazepine
Phenytoin
Phenobarbital
Promidone
Oxcarbazepine
Topiramate
Esclicarbazepine
Best contraception for epilepsy
Copper IUD
Mirena IUS
Injections
Increased risk of seizure with estrogen containing contraception
Lamotrigine
Risk of congenital malformations in epilepsy
- Precious child with major malformation (16.8)
- Polytherapy (16.7)
- Sodium valproate
- Carbamazepine <400mg
- Lamotrigine <300mg
Haemophilia
Factor VIII and IX levels
> = 0.5iu/ml for invasive testing, surgical procedures, miscarriage
=1.0 iu/ml treatment
VWF factor levels
> =0.5 iu/ml surgical procedures, miscarriage
= 1.0 iu/ml target post procedure level
Level for treatment
Factor II, V, VII
0.2 iu/ml surgical procedures
Factor X deficiency level for treatment
0.3
Fibrinogen levels treatment in pregnancy
< 0.5 consider prophylaxis