Maternity and Newborn Medication (Chap 35) Flashcards
(32 cards)
Tocolytics
Tocolytics are medications that produce uterine relaxation and suppress
uterine activity in an attempt to halt uterine contractions and prevent preterm birth
Tocolytic medication Indomethacin
Indomethacin (Indocin)
relaxes uterine smooth muscle
Tocolytic medication: Magnesium sulfate
central nervous system depressant
- relaxes smooth muscle, including the uterus
- used to halt preterm labour contraction
- also used for preeclamptic clients to prevent seizures
Tocolytic medication: Nifedipine
Nifedipine (procardia, adalat, nifedical)
calcium channel blocker, relaxes smooth muscle including the uterus by blocking calcium entry
Tocolytic medication: Terbutaline
adrenergic agonist
- relaxes smooth muscle, inhibiting uterine activity and causes brocholilation
What is the antidote to magnesium sulfate?
Calcium Gluconate
True or False
Magnesium Sulfate is contraindicated for clients that have kidney disease?
TRUE
What is the target range for Magnesium Sulfate?
4-7.5 mEq/L
What would be given to a client in preterm labor between 28 and 32 weeks’ gestation whose labor
can be inhibited for 48 hours without jeopardizing the mother or fetus
Betamethasome (Celestone) and Dexamethasone
It is a corticosteroids that increase the production of surfactant to accelerate fetal lung maturity and reduce the incidence or severity of respiratory distress
syndrome
What type of medication during pregnancy can produce withdrawal symptoms in the newborn?
Opioid Analgesic
What are some symptoms of newborn withdrawn?
irritability, excessive crying, tremors, hyperactive refleces, fever, vomiting, diarrhea, yawning, sneezing and seizures
What is the antidote for opioids?
Naloxone (Narcan)
Name some opioid analgesic medication given to women for pain during labour?
Meperidine Hydrochloride (Demerol) Hydromorphone Hydrochloride (Dilaudid)
Why wouldn’t you give opioid medication to a women that is in labour?
it can slow the labour process and if the medication is not adequately removed from the fetal circulation, respiratory depression can occur
What types of medication ripen the cervix and make it softer causing it to begin to dilate and efface?
Prostaglandins
- they stimulate uterine contractions and are administered vaginally
Name 2 prostaglandin medications:
Misoprostol (Cytotec)
Dinoprostone (Cervidil)
How many hours after prostaglandin therapy can you administer a uterine stimulant? (Oxytocin/Pitocin)
6-12 after the discontinuation of prostaglandin therapy
What medication stimulates the smooth muscles of the uterus and increases the force, frequency and duration of uterine contractions?
Oxytocin (Pitocin)
Oxytocin also promotes __________.
milk letdown
What medication:
- Induces or augments labor
- Controls postpartum bleeding
- Promotes milk letdown and facilitates breast-feeding (intranasal route)
- Manages an incomplete abortion
Oxytocin (Pitocin)
Rh0(D) Immune Globulin (RhoGAM, WinRho) is given to prevent antibody formation is most successful if the medication is given at _____ weeks and again within _____ hours after delivery
28 weeks
72 hours after delivery
What is Phytonadione?
Vitamine K
- newborns are deficient in vitamin K for the first 5-8 days of life because of the lack of intestinal bacteria
The nurse is monitoring a client who is receiving oxytocin (Pitocin) to induce
labor. Which assessment finding would cause the nurse to immediately
discontinue the oxytocin infusion?
1. Fatigue
2. Drowsiness
3. Uterine hyperstimulation
4. Early decelerations of the fetal heart rate
- Uterine hyperstimulation
Oxytocin stimulates uterine contractions and is a common pharmacological method to induce labor.
High-dose protocols have been associated with more uterine hyperstimulation and more cesarean births related to
fetal stress. Some health care providers prescribe the administration of oxytocin in 10-minute pulsed infusions rather
than as a continuous infusion. This pulsed method, which is more like endogenous secretion of oxytocin, is reported
to be effective for labor induction and requires significantly less oxytocin use. Adverse effects associated with
administration of the medication are hyperstimulation of uterine contractions and nonreassuring fetal heart rate
patterns. Oxytocin infusion must be stopped when any signs of uterine hyperstimulation are present. Drowsiness
and fatigue may be caused by the labor experience. Early decelerations of the fetal heart rate are a reassuring sign
and do not indicate fetal distress.
A pregnant client is receiving magnesium sulfate for the management of
preeclampsia. The nurse determines that the client is experiencing toxicity from
the medication if which finding is noted on assessment?
1. Proteinuria of 3 +
2. Respirations of 10 breaths/minute
3. Presence of deep tendon reflexes
4. Serum magnesium level of 6 mEq/L
- Respiration of 10 bpm
Magnesium toxicity can occur from magnesium sulfate therapy. Signs of magnesium sulfate toxicity
relate to the central nervous system depressant effects of the medication and include respiratory depression, loss of
deep tendon reflexes, and a sudden decline in fetal heart rate and maternal heart rate and blood pressure.
Therapeutic serum levels of magnesium are 4 to 7.5 mEq/L. Proteinuria of 3 + is an expected finding in a client with
preeclampsia.