MCBG genetics topic 12

Question 1

gene definition

Answer 1

stretch of DNA sequence at specific chromosomal location that carries the code for a polypeptide or untranslated RNA

Question 2

phenotype definition

Answer 2

characteristics

Question 3

State the blood types and describe the safe transfusions TO and FROM

Answer 3

A- to AB or A. from A or O
B- to AB or B. from B or O.
AB- to AB only. from all.
O- no antigens so safe to transfuse to all. only accept O

Question 4

state the genotypes of the different blood groups. which are co dominant?

Answer 4

A- IAIA or IAIO
B-IBIB or IBIO
AB- IAIB
O-IOIO

AB go dominant.
A and B dominant over O

Question 5

in which type of inheritance can the disease skip generations

Answer 5

autosomal recessive

Question 6

what is polygenic inheritance. give disease example

Answer 6

more than one gene can be involved in producing a phenotype

albinism- recessive but relies on two genes.

Question 7

what are linked genes?

Answer 7

genes on the same chromosome
don’t show independent assortment at meiosis
Very close together= no/little crossing over (recombination frequency)