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Flashcards in MCQ Deck (48)
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1

observation that exposure to cowpox protected milkmaids from smallpox marked the beginning of

vaccination

2

'immunital' derived from

latin - 'protection'

3

patient with recurrent infections - what should doctor suspect

immune disorder

4

we need at least two general mechanisms to fight infection: one extracellular, one intracellular

true

5

what is an 'atopic' subject

can over work sometimes

6

what was Jenner first to demonstrate systemically

that interspecies (cross) reaction could be used for protection

7

do other living organisms have an immune system

all have immune system

8

DNA restriction enzymes found in bacteria for

essential part of their immune system

9

primary purpose of immune reactions

defend against pathogen

10

can salt or water be haptens

never

11

what is a hapten

relatively small molecule that elicit immune response when attached to larger carrier e.g. protein

12

Gowan's and co-workers using thoracic duct drainage where animal lymph diverted, observed test animals unable to respond to antigen challenges and failed to recognise grafts. what was function restored by

WBC replenishment

13

what is the primary site that supports differentiation of the I. D. stem cells

bone marrow - adults
liver - foetus

14

where is your thymus

near neck coronary arteries

15

peyers patch function

sampling and surveillance of Ag at intestine

16

what is considered 'cemetery of RBC'

spleen

17

what is the thrombus mainly composed of

fibrin and platlets

18

where are albumin, fibrinolytic proteins and complement mainly synthesised in

liver

19

during break down of thrombus, which enzyme mainly causes fibrin degradation

plasmin

20

which AB isotype classes mainly involved in classical pathway of complement activation

IgG1, IgG3, IgM

21

which list of functions best describe sequence of events in inflammation

white reaction, red reaction, flare, wheal

22

diabetes type 1 in which insulin producing beta cells are destroyed by immune system is classical example of

autoimmune disease

23

difference between adaptive and innate immunity

innate response not amplified
i.e. reaction is same with repeated infections

24

opsonisation, anaphylatoxins and membrane cell lysis are main biological functions of

complement system

25

what neutralises free virus in body

antibody

26

which vaccine is safest to use

inactivated

27

indirect mechanism of tissue damage in kidneys by hep. malaria and most acute infections is forming

immune complexes

28

on skin, large number bacteria - why can't pathogenic ones colonise tissue

low pH, antibacterial, microflora present

29

what are: langerhans cells, veiled cells, Kupfer cells

DC

30

where are neutrophils made

in bone marrow