Mcqs Flashcards

1
Q
  1. A folic acid deficiency would interfere with the synthesis of which of the following amino acids from the indicated precursors?
A

Glycine from glucose and alanine

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2
Q
  1. Which of the following characterize α-helix regions of proteins?
A

Which of the following characterize α-helix regions of proteins?

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3
Q
  1. Which of the following is a characteristic of globular proteins?
A

Tertiary structure is formed by hydrophobic and electrostatic interactions between amino acid side chains and by hydrogen bonds between peptide bonds

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4
Q
  1. A protein has one transmembrane domain composed entirely of α-helical secondary structure. Which of the following amino acids would you expect to find in the transmembrane domain?
A

Leucine

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5
Q
  1. Autopsies of patients with Alzheimer disease show protein aggregates called neurofibrillary tangles and neuritic plaques in various regions of the brain. There plaques exhibit the characteristic staining of amyloid. Which of the following structural features is the most likely characteristic of at least one protein in these plaques?
A

A high content of B-pleated sheet structure

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6
Q
  1. Which one of the following enzymes can fix ammonia into an organic molecule?
A

Glutamate Dehydrogenase

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7
Q
  1. Pyridoxal phosphate, which is required for transaminations, is also required for which of the following pathways?
A

Glycogenolysis

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8
Q
  1. In a polypeptide at physiologic pH, hydrogen bonding may occur between:

A) the side chains of a leucine residue and a lysine residue.
(B) the side chains of an aspartyl residue and a glutamyl residue.
(C) the terminal _-amino group and the terminal _-carboxyl group.
(D) the amide group in the peptide bond and an aspartyl side chain.
(E) the SH groups of two cysteine residues.

A

D. The amide group in the peptide bond and an aspartyl side chain.

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9
Q
  1. Which of the following shows the linear sequence of atoms joined by covalent bonds in a peptide backbone?

(A) -N-C-C-N-C-C-N-C-C.
(B) -N-C-O-N-C-O-N-C-O-.
(C) -N-C-C-O-N-C-C-O-N-C-C-O-.
(D) -N-H-C-C-N-H-C-C-N-H-C-C-.
(E) -N-H-C-O-H-N-H-C-O-H-N-H-C-C-.

A

A. -N-C-C-N-C-C-N-C-C.

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10
Q
  1. List the Biochemical functions of hormones .
A

A. Severe stress adaptation
B.

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11
Q
  1. The following are steps involved in the biosynthesis of catecholamines except….
A

B. Decarboxylation by tyrosine hydroxylase

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12
Q
  1. The following are the primary features of hypothyroidism except …
A

Serum T3/T4 levels are high , but TSH levels are low due to a lack of negative
feedback effects .

Note that a primary feature of primary hypothyroidism in this case would be
“Serum T3/T4 levels are low but TSH levels are high due to a lack of negative feedback effects

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13
Q
  1. Does Amiodarone cause hypothyroidism
A

Yes

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14
Q
  1. Which of the following changes would occur if an acidic solution is added to a buffer solution
A

The system would form more acid .

Note reason :

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15
Q

An increase in partial pressure of CO2 in the lungs would result in which of the following ?

A

Decrease in the pH of the blood

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16
Q

The replication of two daughter DNAs ,each of which contains one old strand and one new strand is called ….

A

Semi-conservative replication

17
Q

Which of the following can be used to join blunt ends of a DNA fragment to a vector

A

T4 Ligase

18
Q

The major difference between High density Lipoprotein and Low density Lipoprotein is …..

A

High Density Lipoprotein (HDL) contains Apolipoprotein-A ( APOA)

19
Q

Which of the following is a congenital non- haemolytic jaundice

A

Crigler -Najjar Syndrome

20
Q

The unit of segregation of replicated dna is

A

Replicon

21
Q

The unit of segregation of replicated dna is

A

Replicon