Mechanics of ventilation 2 Flashcards

(37 cards)

1
Q

tidal volume - TV

A

amount of air inhaled or exhaled during normal quiet breathing w/o effort

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2
Q

inspiratory reserve volume - IRV

A

The maximum amount of air that can be inhaled after a quiet inhale

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3
Q

expiratory reserve volume - ERV

A

the amount of air that can be exhaled with maximum effort after normal inhalation

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4
Q

residual volume - RV

A

the amount of air remaining in the lungs after maximum exhalation

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5
Q

inspiratory capacity

A

maximum amount of air that can be inhaled - IRV
after quiet inhalation - TV
TV + IRV

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6
Q

Functional residual capacity

A

the amount of air remaining in the lungs - RV after quiet exhalation - ERV

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7
Q

Total lung capacity

A

RV + ERV + TV + IRV

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8
Q

Vital capacity

A

amount of air that can be exhaled w/ max effort - ERV after maximum inhalation - TV + IRV
cane be forced FVC or slow

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9
Q

FEV1 - Forced Expiratory Volume

A

amount of air that is exhaled during 1st second of forced exhalation after full inhalation

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10
Q

normal FEV1/FVC ratio

A

70-80%

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11
Q

low FEV1/FVC ratio indicates

A

increased lung resistance

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12
Q

how is inspiratory restrictive disease evident in spirometers

A

reduced lung compliance - limited lung expansion during inhalation
significant decrease in IRV and TV only

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13
Q

example of restrictive inspiratory disease

A

fibrosis -

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14
Q

how is expiratory restrictive disease evident in spirometers

A

weakness of accessory muscles in deep exhalation
decreased lung volumes - ERV,
and TLC

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15
Q

Signs of obstruction in spirometer

A

increased lung resistance, making it harder and slower to breath out - causes increased residual lung volume
normal vital capacity
reduced FVC

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16
Q

helium dilution technique

A

spirometer - V1 contains a measured conc of helium - C1
patient starts breathing in normal outside air in normal tidal volume
when the patient is at the functional residual capacity patient begins to inhale helium/air mixture until the air mixture has reached equilibrium with the tank and the patients lungs - FRC = V2 - V1
V2 = FRC + V1
volume of lungs - V2
Helium conc in lungs = C2

17
Q

Initial amount of helium calculation

A

conc of helium = C1
Volume of spirometer = V1
C1 X V1

18
Q

Final amount of helium calculation

A

C2 (V2 + FRC)

19
Q

FRC calculation using the helium dilution method

A

C1 x V1 = C2 x V2
V2 = V1 + FRC
C1 x V1 = C2 x (V1 + FRC)
FRC = (C1 x V1)/C2 – V1

20
Q

Process of body plethysmography

A

Patients sits in a “body box” (airtight chamber) and breathes through a mouthpiece
At FRC, the mouthpiece is closed
Patient tries to breathe in

21
Q

consequences of body plethysmography

A
  • Chest and lungs expand, pressure in lungs drop as volume increases
    • Expanding chest compresses the air inside the chamber, air volume in chamber decreases, pressure in chamber increases
22
Q

key principle in body plethysmography

A

Boyles law

P1V1 = P2V2

23
Q

how can Boyle’s law to find ∆V

A

Change in lung volume: trying to find FRC and therefore ∆V
FRC = FRC + ∆V
Change of air volume in box:
V1 = V1 - ∆V
Change of pressure in box:
P1 = P1 + ∆P
P1 x V1 = (P1 + ∆P) x (V1 - ∆V) [Boyle’s Law]
- P1 x V1 = P1 V1 + ∆P V1 - ∆V P1 - ∆P ∆V
- ∆V = ∆P V1/ (P1+ ∆P)

24
Q

how can Boyles law be used to find FRC in body plethysmography

A

P1 x FRC = (P1 - ∆P) x (FRC + ∆V) [Boyle’s Law]

FRC = ∆V(P1- ∆P)/ ∆P

25
lung volumes vary with
``` body size age sex muscular training posture race respiratory diseases ```
26
dead space
the volume occupied by gas in the lungs which does not participate in gas exchange.
27
3 types of dead space
anatomical dead space physiological dead space alveolar dead space
28
calculating dead space volume
tidal volume - alveolar volume
29
alveolar dead space
Air in alveoli that are surrounded by pulmonary capillaries without blood flow
30
when can alveolar dead space increase
pulmonary embolism
31
physiological dead space calculation
Anatomical Dead Space + Alveolar Dead Space
32
fowlers method nitrogen washout
messures conc of nitrogen exhaled inspiration - N2 decline rapidly exhalation - inclines rapidly but not to the same - mixture of dead space and alveolar gas magnitude and plateau
33
phase 1 of fowlers method
low N2 - end of inspiration all of the dead space air - air in alveoli w/ no blood vessel to diffuse air into only oxygen that has been exhaled
34
phase 2 of fowlers method
mix of dead space air and alveolar space air
35
Bohrs method
VT x PeCO2 = VA x PaCO2 | tidal volume x expire partial pressure of CO2 = Alveolar space x partial pressure of CO2 in arterial blood of alveoli
36
how can we use Bohrs method to find dead space
``` VT x PeCO2 = VA x PaCO2 VT = VA + VD -> VA = VT - VD Replace VA with VT - VD VT x PeCO2 = (VT - VD) x PaCO2 VD = VT x [(PaCO2 - PeCO2)/PaCO2] ```
37
Pul. Ventilation
VT x f = VT x RR VT = Tidal volume [L] f = RR = respiratory frequency, respiratory rate [min-1