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HIV > Mechanism of Action / Class > Flashcards

Mechanism of Action / Class Flashcards

1
Q

Abacavir

A

NRTI - guanacine analogue
Block HIV RNA conversion to HIV DNA

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2
Q

Emtricitabine

A

NRTI - cytosine analogue
Block HIV RNA conversion to HIV DNA

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3
Q

Lamivudine (Epivir)

A

NRTI - cytosine analogue
Block HIV RNA conversion to HIV DNA

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4
Q

Zidovudine (Retrovir)

A

NRTI - thymidine analogue
Block HIV RNA conversion to HIV DNA

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5
Q

Tenofovir disoproxi fumarate (Viread)

A

NRTI - adenosine analogue
Block HIV RNA conversion to HIV DNA

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6
Q

Bictegravir (Biktarvy)

A

Integrase Strand Transfer Inhibitor - blocks HIV DNA from inserting into host DNA

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7
Q

Raltegravir (Isentress)

A

Integrase Strand Transfer Inhibitor - blocks HIV DNA from inserting into host DNA

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8
Q

Elivitegravir (Stribild, Genvoya)

A

Integrase Strand Transfer Inhibitor - blocks HIV DNA from inserting into host DNA

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9
Q

Dolutegravir (Tivicay)

A

Integrase Strand Transfer Inhibitor - blocks HIV DNA from inserting into host DNA

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10
Q

Rilpivirine

A

NNRTI to prevent HIV RNA conversion to HIV DNA

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11
Q

Efavirenz

A

NNRTI to prevent HIV RNA conversion to HIV DNA

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12
Q

Atazanavir (Reyataz)

A

Protease Inhibitors block the budding and maturation of the HIV protein chain

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13
Q

Darunavir (Prezista)

A

Protease Inhibitors block the budding and maturation of the HIV protein chain

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14
Q

Ritonavir (Norvir)

A

Protease Inhibitior used at low doses at a CYP3A4 inhibitor to block ART metabolism

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15
Q

Cobicistat

A

CYP3A4 inhibitor to block metabolism of ART (specifically protease inhibitors and elvigravir)

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16
Q

Maraviroc

A

CCR5 antagonist on viral cell to block the HIV from binding to CD4 host cell

17
Q

Fostemsavir

A

gp120 inhibitor - binds to HIV envelope to block binding on CD4 cell

18
Q

Ibalizumab

A

Binds CD4 receptors to block binding of virus to CD4 cells

19
Q

Enfuviritide

A

Blocks fusion of virus into CD4 host cell

HIV (3 decks)

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