Mechanisms Flashcards

(56 cards)

0
Q

By ions via gap junctions

A

Direct

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1
Q

What are the Mechanisms of Intercellular Communication?

A
  • Direct
  • Paracrine
  • Endocrine
  • Synaptic
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2
Q

By Paracrine factors via the extra cellular fluid

A

Paracrine

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3
Q

By hormones via the blood circulatory system

A

Endocrine

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4
Q

By neurotransmitters across neural junctions

A

Synaptic

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5
Q

What are the Endocrine Glands

A
Hypothalamus
Pituitary Gland
Pineal Gland
Thyroid Gland
Parathyroid Gland
Adrenal Gland 
Pancreas
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6
Q

what are the Endocrine Tissues in Organs

A
Intestines
Kidneys
Liver
Heart
Thymus
Gonads 
Placenta 
Adipose Tissue
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7
Q

A very defined structure of Tissues are

A

Endocrine Glands

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8
Q

A group of cells that are found within organs

A

Endocrine Tissues in Organs

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9
Q

Hormones are ___ ____ of various body functions such as _____ and _____. They are ___ into and transported by the blood to affect the ____ of their ____. Hormones are ____ for certain ____ cells because hormones bind to _______ on their target ___.

A

Chemical regulators; growth; reproduction
Secreted;functions; target cells
Specific; target cell; specific receptors; cell

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10
Q
Compounds acting as hormones are classified according to their \_\_\_\_\_\_ as:
1)
2)
3)
4) 
5)
A
Chemical structure;
Steroids
Monoamines 
Oligopeptides
Glycoproteins
Polypeptides
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11
Q

Made from lipids or cholesterol

A

Steroids

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12
Q

Vitamin D is a

A

Steroid

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13
Q

Made from a single amino acid which is modified or repeated

A

Monoamines

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14
Q

A thyroid hormone is

A

Monoamines

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15
Q

Made from 3 - 10 amino acids

A

Oligopeptides

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16
Q

Oxytocin is what

A

Oligopeptides

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17
Q

Made from carbohydrates - proteins complexes

A

Glycoproteins

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18
Q

Luteinizing hormone

A

Glycoproteins

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19
Q

Made from 14-199 amino acids

A

Polypeptide

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20
Q

Insulin and glucagon

A

Polypeptide

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21
Q

What is a hormone receptor

A

they are protein molecules located on the cell membrane, cytoplasm, or nucleus

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22
Q

Steroid hormones bind to ____ associated with _____.

A

Nuclear receptors ; DNA transcription

23
Q

Thyroid hormones bind to _____ on ____ or ____.

A

Cytoplasmic receptors; mitochondria; ribosome

24
What hormones bind to cell membrane receptors and activate second messenger systems?
All other hormones
25
Hydrophilic
Has a strong attraction to water not fat
26
Hydrophobic
Having little to no attraction to water
27
When blood level of the endocrine gland hormone reach an optimum value, it inhibits secretion of the hypothalamic and anterior pituitary hormones that stimulate the endocrine gland.
Negative Feed back control of secretion
28
When action of an endocrine gland hormone reach an optimum level, it increases the secretion of the hormone that stimulated the action.
Positive Feed Back control of Secretion
29
What is a central area of the basal brain limbic system
The Hypothalamus
30
The Hypothalamus consist of a large number of ____ that modify and control the body functions VIA _____.
Nuclei; The Hypothalamic Hormones
31
What are the hypothalamic hormones
1) GHRH 2) GHIH 3) PRH 4) PIH 5) CRH 6) TRH 7) GnRH 8) OT
32
GHRH
Growth Hormone Releasing Hormone
33
GHIH
Growth Hormone Inhibiting Hormone (somatostatin)
34
PRH
Prolactin Releasing Hormone
35
PIH
Prolactin Inhibiting Hormone (Dopamine)
36
CRH
Corticotropin releasing hormone
37
TRH
Thyrotropin releasing hormone
38
GnRH
Gonadotropin releasing hormone
39
ADH
Anti diuretic hormone
40
OT
Oxytocin
41
Pituitary Gland
A small gland that is connected to the hypothalamus by the infundibulum
42
What are the two parts of the pituitary gland
``` Anterior pituitary (adenohypophysis) Posterior Pituitary (neurohypophysis) ```
43
____ derived from the neural brain tissue and connects to hypothalamus by the hypothalamic hypophyseal tract axons
Posterior Pituitary
44
____ derived from ectodermal tissue in the roof of the embryonic mouth and connects to the hypothalamus by the hypothalamic hypophyseal portal system
Anterior Pituitary
45
Oxytocin OT
Made in the hypothalamus then stored and secreted from the posterior pituitary
46
Oxytocin target tissues are the ____ of the reproductive systems in both male and females
Smooth muscle
47
What does oxytocin stimulate
- semen propelling during ejaculation - uterine contractions during labor - milk ejection during nursing
48
Antidiuretic Hormone (ADH) (Vasopressin)
Made in the hypothalamus them stored and secreted from the posterior pituitary
49
ADH target tissues are ___ and ____
Kidneys and blood vessels
50
What does ADH do
- increases water reabsorption in the kidneys to increase blood volume - causes vasoconstriction of blood vessels to increase blood pressure
51
Human Growth Hormone (hGH) secretion is controlled by hypothalamic ____ and ____
GHRH | GHIH
52
hGH targets all cells especially where?
Skeletal and muscle tissues
53
What does hGH stimulate
1) directly stimulates stem cells growth and differentiation | 2) stimulates liver synthesis and release of somatomedins
54
____ mediated growth hormone functions by stimulating stem cells growth and differentiation
Somatomedins
55
What is the result of somatomedins
Results in growth to adulthood and maintenance of skeleton and muscles during adulthood.