Med Pharm 1 Flashcards
(121 cards)
1
Q
Contraindication for Epi
A
Hypovolemic Shock
2
Q
Duration of Epi
A
5-10 min
3
Q
Peds dose Epi
A
0.01 mg/kg MAX 0.3 mg
4
Q
Onset for epi
A
1-2 iv
5-10 im
5
Q
Diphenhydramine drug class
A
Antihistamine(H1 blocker)
6
Q
MOA benadryl
A
Blocks H1 histamine receptors in the respiratory tract, blood vessels and GI smooth muscle
7
Q
CINC Benadryl
A
Hypersensitivity
MAO inhibitors
Newborns/ nursing mothers
Glaucoma
8
Q
Peds benadryl dose
A
1 mg/kg MAX 300 mg/day
9
Q
Side effects benadryl
A
Drowsiness
Palpitations
Hypotension
Dry mouth/ throat
10
Q
Onset Benadryl
A
15-30, peak 1-3 hrs
11
Q
Duration benadryl
A
3-12 hrs
12
Q
Max daily dose of benadryl
A
400mg/day
13
Q
Methylprednisolone class
A
Corticosteroid, Gluccorticoid
14
Q
MOA Methylprednisolone
A
Suppress inflammation. Potentiates vascular smooth muscle relaxation by beta-adrenergic agonists
15
Q
Indications of Methylprednisolone
A
Anaphylaxis
Acute spinal cord injurt
Adrenal insufficiency
16
Q
CIDC Methylprednisolone
A
GI bleed, diabetes, severe infection
17
Q
Solumedrol dose
A
40-125 mg
18
Q
Peds solumedrol dose
A
1-2 mg/kg
19
Q
Onset solumedrol
A
1-2hrs
20
Q
Methylprednisolone duration
A
8-24 hrs
21
Q
Side effects of Methylprednisolone
A
HTN, HYPOkalemia, HA, sodium+water retention
22
Q
Motrin MOA
A
Reduces hormones that cause inflammation and pain in the body
23
Q
Motrin for AMS prevention
A
600 mg q 8hr
24
Q
Motrin for HA at altitude
A
Does not improve FULL spectrum of AMS or treat HACE
25
Motrin max dose
3200 mg
26
Motrin side effects
Hemorrhage, decreased hemoglobin, eosinophilia, HTN
27
Tylenol drug class
Analgesic, antipyretic
28
MOA tylenol
Increases pain threshold and reduces fever by acting on the hypothalamus
29
What is an antipyretic
Fever reduction
30
Tylenol side effects
Hepatoxicity
31
Max dose tylenol
4000 mg
32
Tylenol dose
325-650
33
peds tylenol dose
15mg/kg
34
What is diamox
Acetazolamide
35
Diamox drug class
Carbonic anhydrase inhibitor
36
MOA Diamox
Decreases H+ ion secretion in renal tubule which in turn alkalizes urine and increases excretion of bicarb, sodium, potassium, and water
37
CIDC Diamox
Sulfa allergy
38
Side effects of Acetazolamide
Paresthesias in extremities, tinnitus, anorexia, taste alteration, polyuria, drowsiness, confusion
39
What is dexamethasone?
Decadron
40
Drug class of dexamathasone
Corticosteroid
41
MOA dexamethasone
Decreases inflammation, suppresses normal immune response
42
IDC Decadron
Ulcerative colitis, HACE, AMS
43
CIDC Dexamethasone
Fungal Infections
44
Decadron Antiinflammatory dose
0.75-9 mg / day PO
OR
0.5-9mg IV/IM every 12 hrs
45
Decadron AMS/HACE dose
AMS: 4mg/6hrs
HACE: 8 mg at once then 4 mg/6 hrs
46
Side effects Dexamethasone
Infection susceptibility
Adrenal suppression and cushing syndrome
47
Nifedipine Drug class
CCB
48
What is nifedipine
Procardia
49
Procardia MOA
Reduces pulmonary vascular resistance and PA pressure as well as systemic resistance and blood pressure. Slightly improves PaO2
50
IDCs Nifedepine
HAPE
51
CIDCs Procardia
Hypotension
52
Nifedipine Dose
30 mg ER every 12
20 mg NR every 8
53
Side effects of nifedipine
Dizziness, flushing, HA, weakness, muscle cramps. N
54
Narcan MOA
Competitive opiate antagonist
55
Narcan dose adults
0.4-2 mg
10 mg
56
Peds Narcan dose
0.1 mg/kg with a max of 2 mg per dose
57
Flumazenil drug class
Benzo antagonist, antidote
58
Flumazenil MOA
Competitively inhibits the activity at the benzodiazepine receptor site on the GABA/benzodiazepine receptor complex
59
CIDCs Flumazenil
TCAs
Chronic use
Cocaine/stims
Known seizure disorders
60
Flumazenil adult Dose
0.2 mg over 15s
0.3 mg over 30
0.5 mg over 30
Repeat at 1 min for MAX DOSE OF 3 mg
61
Pralidoxime Drug class
Cholinesterase reactivator and antidote
62
MOA Pralidoxime
Reactiviates ACH-as which allows AC to be degraded and relives parasympathetic overstimulation
63
IDCs 2PAM
Organophosphates
64
Adult dose 2PAM
600 mg IM
1-2 IV
65
Ped dose 2Pam
20-50 mg IV
66
Side effects of Pralidoxime
Tachy all the way, laryngospams, hypervent, nausea, weakness
67
Atropine drug class
Anticholinergic
68
MOA atropine
Inhibits actions of ACH
69
IDCs Atropine
Organophosphate or nerve gas
70
CIDC atropine
Hypothermia
71
Atropine adult
1-5 mg 3-5 min
72
Atropine PEDS
0.05-0.1 mg/kg
73
Adult dose activated charcoal
1g/kg
74
Ped dose activated charcoal
0.5-1 g/kg
75
Calcium chloride drug class
Electrolye, hypertonic solution
76
MOA Calcium chloride
Increases cardiac contractions
77
IDCs Calcium chloride
CCB OD
78
CIDC Calcium chloride
digitalis toxicity, HYPERcalcemia
79
CaCl adult dose
500-1000mg of 10%
80
CaCl ped dose
20 mg/kg(1000mg MAX)
81
NaHCO3 Drug class
pH buffer, alkalizing agent, electrolyte supplement
82
MOA NaHCO3
Decreases plasma hydrogen ion concentration 🡪 blood pH rises
83
NaHCO3 IDCs
TCA OD
84
CIDC NaHCO3
Suspected metabolic and resp alkalosis
85
Dose for NaHCO3
1mEq/kg for adult and kiddos
86
Side effects NaHCO3
metabolic alkalosis
Seizures
87
Drug class glucagon
Pancreatic hormone
88
Glucagon MOA
Positive inotropic action on the heart even in the presence of beta blockade or calcium channel blockade
89
IDC glucagon
BB OD
CCB OD
90
Glucagon adult dose
3-10 mg over 3-5 min followed by 3-5 mg/hr
91
Glucagon ped dose
0.05-0.15 mg/kg administered the same as adults
OR
0.5-1 mg IM
92
Ondansetron drug class
antiemetic
93
MOA Zofran
Blocks receptors found centrally in chemoreceptor trigger zone and peripherally at the vagal nerve terminals in intestines, minimizing N/V
94
Ped dose Zofran
0.15 mg/kg
95
Promethazine drug class
Antihistamine,antiemetic
96
Promethazine MOA
H1 receptor antagonist that blocks the actions of histamine by competitive antagonism at the H1 receptor. Has anticholinergic properties
97
Promethazine CIDCs
Alcohol, barbs, narcs
98
Phenergan is
Promethazine
99
Phenergan adult dose
12.5-25 mg in 10cc given over 10-25 min
100
Phenergan ped dose
Don't use BUT:
0.25-.5 mg/kg
101
Immodium MOA
Inhibit peristalsis and prolong transit time; reduces fecal volume, increases viscosity, and diminishes fluid and electrolyte loss
102
Immodium MOA
Inhibit peristalsis and prolong transit time; reduces fecal volume, increases viscosity, and diminishes fluid and electrolyte loss
103
CIDC Loperamide
Ulcerative colitis, bloody or tarry stools, diarrhea with a high fever, or diarrhea caused by antibiotic medication
104
Dose for loperamide
4mg after first loose stool then 2 mg after each MAX 16 mg/day
105
Metaclopramide is
Reglan
106
Metaclopramide drug class
Antiemetic, prokinetic GI agent
107
Metaclopramide MOA
Decreases biliary, gastric, and pancreatic secretions
108
IDCs metaclopramide
N/V/GERD
109
CIDC metaclopramide
GI bleed or obstruction, seizure disorder, hypersensitivity
110
Metaclopramide adult dose
10 mg
111
Peds reglan dose
0.1mg/kg
112
Prilosec is
omeprazole
113
Omeprazole drug class
Antiulcer/PP inhibitor
114
MOA Prilosec
suppresses gastric basal and stimulated acid secretion
115
IDCs Prilosec
GERD, erosive esophagitis, Gastric ulcer, Heartburn (OTC)
116
CIDC Omeprazole
hypersensitivity
117
Other PPIs
Esomeprazole-nexium
Lansoprazole-prevacid
Pantoprazole-protnix
118
ranitidine is
prozac
119
Ranitidine drug class
antiulcer, H2 antihistamine
120
MOA randitidine
Decreases volume and concentration of gastric acid
121
IDC prozac
GERD, fastric ulcers, UGI bleed
