Medbridge + ASHT nerve compression Flashcards
(54 cards)
what is Epineurium?
thick sheath of connective tissue that cushions the nere and facilitates nerve gliding, outermost covering
what is Perineurium?
surrounds the fascicles, provides a barrier to prevent toxins from getting in. Surgical repair of nerve lacerations involved repair at the fascicles
what is endoneurium?
surrounds each individual axon. Consists of arteriae nervorum: intrinsic blood supply to the nere fibers (vasa nervorum) and Neri Nervorum: intrinsic n. supply to nerve fibers
what are Mechanisms of nerve injury?
mechanical: traction, compression, laceration, combination thermal/electrical: chemical, ischemic, radiation, injection Secondary injuries: infection, scarring, fracture callus, ischemia
what is Neurapraxia?
acute compression results in local contusion. Conduction block. Mild neuropraxia leads to transient ischemia. Epineurium, perineurium, endoneurium intact. Excellent prognosis
what is Axonotmesis?
loss of axonal continuity. Connective tissue intact but degeneration of injured axon distal. recovery prolonged but good bc endoneurial tubes are intact so no miswiring.
what is Neurotmesis?
most severe nerve injury - complete transection. all axons and connective tissue severed. No spontaneous recovery, requires surgery.
what is Nerve injury classification from least to most severe?
Neurapraxia/Sunderland 1, axonotmesis/Sunderland 2, neurotmesis/Sunderland 3 4 5
what is Wallerian degeneration?
distal axon fragments and myelin sheath disintegrate
what is Speed of axon regeneration?
1mm/day
what are factors that influence nerve regeneration?
scar tissue, inaccurate alignment of fascicles with surgical repair, delay in reconstruction (atrophy), age, proximal injury
what is the speed of motor endplate degradation ?
1% per week Need 50% to function ~ 1 year/12 months time
what is the Maximum distance from injury to motor end plates to restore function?
35 cm. Sensory lasts longer than motor (365 days at 1mm/day)
what are C-fibers?
No myelin sheath, small (1 micron) . transmit burning pain at 2m/second (slow-moving)
what are A-delta fibers?
have myelin sheath, 2-5 microns in diameter, transmit temperature sensation at 20m/second
what are A-beta fibers?
have myelin sheath, 10-15 microns diameter, transmit light tough sensation at 60m/sec. Supply end organs: pacinian, meissner, merkel cell
what are A- alpha fibers?
have myelin sheath, 15-20 microns diameter, transmit motor function at 60 m/sec
what are Pacinian corpuscles?
quick adapting, deep pressure nerve ending respons to high vibratory stimulus 256 cycles. sense vibration and fine textures
what are Meissner corpuscle?
quick adapting, responds to moving touch and vibration (256). Involved in skin movement, object handling detection
what are Merkel cell neurite complex?
slow adapting, responds to constant touch NOT vibration
Semmes-weinstein Monofilaments
Normal 2.83,
Diminished light touch 3.61,
diminished protective 4.31,
loss of protective 4.56,
deep pressure only 6.65
why does low frequency vibration return poorly after nerve repair?
Pacinian corpuscles reinnervate poorly
Classification of nerve repair
Primary repair <1 week,
delayed primary repair after 3-4 days,
secondary repair >1 week
when to start sensory reeducation?
when any of the following are present:
1. +protective sensation
2. 30 cps vibration
3. moving touch sensation
4. touch perception in fingertips
5. 4.31 semmes-weinstein