Medd

Question 1

What is the active ingredient in Prilosec?

Answer 1

Omeprazole

Question 2

What drug class does Prilosec belong to?

Answer 2

Proton-pump inhibitor (PPI)

Question 3

What are the indications for omeprazole?

Answer 3

Peptic ulcer disease, Dyspepsia, GERD, H. pylori infection

Question 4

What are notable side effects of omeprazole?

Answer 4

Nausea, Diarrhea, Headache, Hypomagnesemia (long-term)

Question 5

What can PPIs such as omeprazole disguise?

Answer 5

The symptoms of gastric cancer.

Question 6

What risk is increased with prolonged courses of omeprazole in the elderly?

Answer 6

The risk of fractures.

Question 7

How does omeprazole affect clopidogrel?

Answer 7

Omeprazole reduces the antiplatelet effects of clopidogrel.

Question 8

Are there any significant food-drug interactions with omeprazole?

Answer 8

There are no significant food-drug interactions with omeprazole.

Question 10

What is the active ingredient in this medicine?

Answer 10

Ciprofloxacin

Question 11

What is the drug class of Ciprofloxacin?

Answer 11

Fluoroquinolone antibacterial

Question 12

What are some brand names for Ciprofloxacin?

Answer 12

Cipro, Proquin

Question 13

What are the indications for Ciprofloxacin?

Answer 13

Skin, bone, or joint infections; urinary tract infections; respiratory infections; gonorrhea

Question 14

What are notable side effects of Ciprofloxacin?

Answer 14

Tendon damage/rupture; QT prolongation; increased risk of seizures; nausea and vomiting

Question 15

How do antacids affect Ciprofloxacin?

Answer 15

Antacids reduce the effectiveness of fluoroquinolones.

Question 16

What is the interaction between NSAIDs and Ciprofloxacin?

Answer 16

NSAIDs increase the risk of seizures with fluoroquinolones.

Question 17

How does Prednisolone affect Ciprofloxacin?

Answer 17

Prednisolone increases the risk of tendon rupture.

Question 18

What types of foods interact with Ciprofloxacin?

Answer 18

Foods that contain multivalent ions (calcium, magnesium, aluminum, zinc) decrease the effectiveness of ciprofloxacin.

Question 20

What is the active ingredient in Zofran?

Answer 20

Ondansetron

Question 21

What drug class does Zofran belong to?

Answer 21

5-H3 antagonist / Antiemetic

Question 22

What are the indications for ondansetron?

Answer 22

Prevent nausea / vomiting due to cancer chemotherapy, radiation, or surgery.

Question 23

What are notable side effects of ondansetron?

Answer 23

Headache, Diarrhea, Sleepiness, QT prolongation

Question 24

What should be avoided when using ondansetron?

Answer 24

Drugs that also prolong the QT interval (antipsychotics, SSRIs, quinine etc.)

Question 25

What is a food-drug interaction with ondansetron?

Answer 25

Grapefruit juice increases the risk of side effects with ondansetron.

Question 27

What is the active ingredient in this medication?

Answer 27

Clozapine

Question 28

What conditions is clozapine indicated for?

Answer 28

Schizophrenia and schizoaffective disorder

Question 29

What is a requirement for dispensing clozapine?

Answer 29

Only certified pharmacies may dispense clozapine. It is a REMS medicine.

Question 30

How many black box warnings does clozapine carry?

Answer 30

Clozapine carries 5 black box warnings.

Question 31

What are the black box warnings associated with clozapine?

Answer 31

Severe neutropenia, orthostatic hypotension, seizures, myocarditis, risk of death in the elderly with dementia-related psychosis.

Question 32

What drug class does clozapine belong to?

Answer 32

Antipsychotic drug

Question 33

What is the brand name for clozapine?

Answer 33

Clozaril

Question 34

What are notable side effects of clozapine?

Answer 34

Agranulocytosis, weight gain/type 2 diabetes, heart inflammation, extrapyramidal effects.

Question 35

What food-drug interaction should be considered with clozapine?

Answer 35

Caffeine can worsen side effects and should be limited or avoided.

Question 36

Tetracycline. Trade name?

Answer 36

Sumycin, Ala-tet, brodspec

Question 37

What is the drug class of Tetracycline?

Answer 37

Antibacterial drug (protein synthesis inhibitor)

Question 38

What are some brand names for Tetracycline?

Answer 38

Sumycin, Ala-Tet, Brodspec

Question 39

What are the indications for Tetracycline?

Answer 39

Acne vulgaris, lower respiratory tract infections, pelvic inflammatory disease, Lyme disease, malaria, typhoid

Question 40

What are notable side effects of Tetracycline?

Answer 40

Tooth discoloration, photosensitivity, esophageal irritation, enamel hypoplasia

Question 41

How do antacids affect Tetracycline?

Answer 41

Antacids reduce the gastrointestinal absorption of tetracycline. Administration should ideally be separated by 4-hours to avoid this drug interaction.

Question 42

Is Tetracycline safe during pregnancy?

Answer 42

Tetracyclines are teratogenic and should be avoided in pregnancy.

Question 43

What food-drug interactions are associated with Tetracycline?

Answer 43

Foods high in multivalent ions (calcium, iron, magnesium, aluminum, zinc) reduce the efficacy of tetracycline.

Question 44

What is the active ingredient in Valtrex?

Answer 44

Valaciclovir

Question 45

What drug class does Valtrex belong to?

Answer 45

Antiviral drug

Question 46

What are the indications for Valtrex?

Answer 46

Herpes virus infections, genital warts, cold sores, shingles, and chickenpox

Question 47

What are notable side effects of Valtrex?

Answer 47

Mild skin pain, rash, itch, headache

Question 48

What food-drug interaction should be noted with Valtrex?

Answer 48

When taken with NSAIDs, it increases the risk of bladder problems.

Question 49

What should be limited for maximum effectiveness of Valtrex?

Answer 49

Alcohol intake

Question 50

What is the active ingredient in Lamictal?

Answer 50

Lamotrigine

Question 51

What are the indications for Lamotrigine?

Answer 51

Focal seizures, Tonic-clonic seizures, Lennox-Gastaut seizures, Bipolar disorder

Question 52

What is the drug class of Lamictal?

Answer 52

Anticonvulsant drug

Question 53

What notable side effects are associated with Lamotrigine?

Answer 53

Skin rash (often serious), Headache, Vomiting, Sleepiness

Question 54

What food-drug interactions should be noted with Lamotrigine?

Answer 54

Tyramine-rich foods can worsen side effects of lamotrigine ## Footnote Examples include aged cheese, certain alcoholic drinks, picked vegetables, etc.

Question 55

What is a significant clinical pharmacology consideration for Lamotrigine?

Answer 55

Lamotrigine significantly increases the blood levels of the anti-arrhythmic drug, dofetilide, and this combination must be avoided.

Question 56

What is the active ingredient in Diflucan?

Answer 56

Fluconazole

Question 57

What class of drug is Diflucan?

Answer 57

Antifungal drug

Question 58

What are the indications for fluconazole?

Answer 58

Severe fungal infections, Histoplasmosis, Candidiasis, Cryptococcosis

Question 59

What are notable side effects of fluconazole?

Answer 59

Increased liver enzymes, Increased risk of seizures, Diarrhea, Vomiting

Question 60

What is a clinical pharmacology concern with fluconazole?

Answer 60

Many drugs increase the risk of torsade de pointes when taken with fluconazole.

Question 61

Can you name some drugs that increase the risk of torsade de pointes with fluconazole?

Answer 61

Donepezil, Pimozide, Voriconazole, Quinidine

Question 62

Are there any serious food-drug interactions with fluconazole?

Answer 62

There are no serious food-drug interactions with fluconazole.

Question 63

What is the active ingredient in Pepcid?

Answer 63

Famotidine

Question 64

What are the indications for famotidine?

Answer 64

Dyspepsia, GERD, Peptic ulcer disease, Zollinger-Ellison syndrome

Question 65

When should famotidine be taken to prevent heartburn and indigestion?

Answer 65

30-60 minutes before eating food or drinking

Question 66

What drug class does famotidine belong to?

Answer 66

Antihistamine

Question 67

What are notable side effects of famotidine?

Answer 67

Headache, Dizziness, Intestinal upset, Constipation or diarrhea

Question 68

Are there any significant food-drug interactions with famotidine?

Answer 68

There are no significant food-drug interactions with famotidine.

Question 69

What is the active ingredient in the medicine?

Answer 69

Cefdinir

Question 70

What is the drug class of cefdinir?

Answer 70

Cephalosporin antibacterial

Question 71

What are the indications for cefdinir?

Answer 71

Strep throat, ear infections, cellulitis, pneumonia

Question 72

What notable side effects are associated with cefdinir?

Answer 72

Nausea, diarrhea, skin rash, vaginal infections

Question 73

What can affect the absorption of cefdinir?

Answer 73

Antacids or iron supplements can make it harder for the body to absorb cefdinir.

Question 74

Are there any significant food-drug interactions with cefdinir?

Answer 74

There are no significant food-drug interactions with cefdinir.