Medical Flashcards
(108 cards)
Cyanokit medication -
Two vials contains 2.5g of hydroxocobalamin. Adults get both vials
= inhibit the parasympathetic nervous system by BLOCKING the action of acetylcholine. Patient are hyper, tachy, fever. Examples Atropine, Antihistamines, antipsychotics, antispasmodics, cyclic antidepressants, mydriatics. Also plants and mushrooms
Anticholinergic drugs
= STIMULATE the parasympathetic nervous system by activating receptors for acetylcholine.
Symptoms = SLUDGE, salivation, lacrimation, urination, defecation, gastrointestinal distress, and eyes (dilation).
Cholinergic drugs
anticholinergic vs sympathomimetic toxidromes
= Both have fever, tachycardia, hypertension, mydriasis and mental status changes. However, anticholinergic patient has dry, red (flushed) skin, constipation and delirium while the sympathomimetic patient has pale, diaphoretic skin, increased GI motility and is typically agitated.
Opioid vs sedative-hypnotic toxidromes
= Opioid toxidrome has miosis and respiratory depression while the sedative-hypnoitic toxidrome have any size pupils and rarely has respiratory depression.
Opioid drugs receptors
= G-protein coupled receptors (GCPR) that are found exclusively in the central nervous system. Withdrawal treated with long acting opioid agonist such as methadone, buprenorphine, clonidine,
Epinephrine, cocaine, amphetamines, MDMA, and over the counter drugs containing ephedrine. Direct stimulation of the alpha- and beta-adrenergic receptors. Restraining may lead to death. Give benzodiazepines (Diazepam)
Sympathomimetic Toxicity
Beta blocker toxicity
- Beta1-receptor blockade impact heart and BP.
- Beta2-receptor blockade inhibits relaxation of smooth muscle in blood vessels, bronchi, etc.
- Bradycardia, hypotension, arrhythmias, hypothermia, hypoglycemia, and seizures.
- We give Glucagon
Calcium Channel Blocker toxicity =
Hypotension, brady-dysrhythmia, and cardiac arrest, depressed level of consciousness. Give activated charcoal
Organophosphate toxicity
= three broad impact categories: Muscarinic effects, Nicotinic effects, Central nervous system
Neuropsychiatric effects.
In Moco we give it with Atropin (called DuoDote kits), doses are for Mild 600mg, Moderate 1200mg, severe 1800
name the effect. fluids coming out - Rhinorrhea, hypersalivation, diaphoresis, incontinence; also bradycardia and respiratory distress
Muscarinic effects =
name the effect: hypertension, tachycardia, cramping
Nicotinic effects
name the effect: anxiety, coma, less breathing
Central nervous system (CNS) effects
name the effect: Impaired memory, confusion, psychosis
Neuropsychiatric effects =
Alcohol-impacted neurotransmitter
- Gamma-aminobutyric acid (GABA) is impacted by ethanol. It’s the primary inhibitory neurotransmitter. It slows down the brain by blocking signals in the central nervous system.
hernia that leads to opening in diaphragm allowing stomach above diaphragm
Hiatal (hai ei tal) -
Field treatment of GI issues =
- Rule out acute MI (12 lead)
- IV access
- Pain management
- Anti-emetic (zofran)
pain during the menstrual cycle
Dysmenorrhea (dis me Noria) =
= unintentionally caused by medical treatment
Iatrogenic (ai·a·truh·jeh·nuhk)
related to digestion
Peptic =
= tumor/ uncontrolled cell growth
Neoplastic
Vomiting of fresh blood
Hematemesis (hema te masis)
= black tarry stools, suggest upper GI bleed
Melena (muh·lay·nuh)
Passing of red blood from rectum
Hematochezia (hema ta kizya)