Medical and Surgical Management of CVD Flashcards

1
Q

ACE inhibitor

A
  • captopril, enalopril, lisinopril
  • inhibit conversion of angiotensin I to angiotensin II
  • decreases Na retention and peripheral vasoconstriction in order to decrease BP
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2
Q

Angiotensin II receptor blockers

A
  • losartan
  • blocks binder of angiotensin II at the tissue/smooth muscle level, decreasing blood pressure
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3
Q

Nitrates

A
  • nitroglycerin
  • decrease preload through peripheral vasodilation, reduce myocardial oxygen demand, reduce chest discomfort
  • may also dilate coronary arteries, improve coronary blood flow
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4
Q

Beta-1 Adrenergic blocking agents

A
  • atenolol, metoprolol, propanolol
  • reduce myocardial demand by reducing heart rate and contractility
  • control arrhythmias, chest pain
  • reduce blood pressure
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5
Q

Calcium channel blocking agent

A
  • Diltiazem, amlodipine
  • inhibit flow of calcium channel ions, decrease heart rate, decrease contractility, dilate coronary arteries, reduce BP, control arrhythmias, chest pain
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6
Q

Antiarrhythmics

A
  • alter conductivity, restore normal hear rhythm, control arrhythmias, improve cardiac output
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7
Q

Digitalis

A
  • cardiac glycosides
  • increase contractility and decreases heart rate; mainstay in the treatment of CHF
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8
Q

Aspirin

A

decreases platelet aggregation
- may prevent MI

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9
Q

Diuretics

A
  • decrease myocardial work (reduce preload and after load)
  • control hypertension
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10
Q
  • Tranquilizers
A
  • decrease anxiety, sympathetic effects
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11
Q

Hypolipidemic agents

A
  • 6 major cholesterol lowering drugs
  • reduce serum lipid level when diet and weight reduction are not effective
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12
Q

Activity restriction for acute MI

A
  • Activity can be increased on the acute MI has stopped (peak in cardiac troponin levels)
  • Limit activity to 5 METs or 70% of age predicted HRmax for 4-6 weeks following MI
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13
Q

Acute heart failure activity restriction

A
  • oxygen demand should not be increased in patients in acute or decompensated heart failure
  • once they have been medicated managed and no longer display signs of acute decompensation, their activity can be gradually increased while monitoring hemodynamic response to activity
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14
Q

Percutaneous transluminal coronary angioplasty

A
  • under fluoroscopy, surgical dilation of a blood vessel using a small balloon-tipped catheter inflated inside the lumen; relieves obstructed blood flow in acute angina or acute MI; results in improved coronary blood flow, improved L ventricular functional, anginal relief
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15
Q

Intravascular stents

A
  • an endoprosthesis (pliable wire mesh) implanted during angioplasty to prevent restenosis and occlusion in coronary or peripheral arteries
  • may be coated with slow release medication to prevent more plaque build up (drug-eluting stent, DES)
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16
Q

Coronary artery bypass graft (CABG)

A
  • surgical circumvention of an obstruction in a coronary artery using an anastomosing graph (saphenous vein, internally mammary artery)
  • multiple grafts may be necessary
  • results in improved coronary blood flow, improved left ventricular functional, anginal relief
17
Q

Transplantation

A

used in end-stage myocardial disease

18
Q

Transplantation - heteroptics

A

involves leaving the natural heart and piggybacking the donor heart

19
Q

transplantation - orthotopic

A

involves removing the diseased heart and replacing it with a donor heart

20
Q

major problems post-transplantaiton

A

rejection, infection, complications of immunosuppressive therapy

21
Q

Ventricular assist device

A
  • an implanted device the improves tissue perfusion and maintains cardiogenic circulation
  • used with severely involved patients
22
Q

Thrombolytic therapy

A
  • administered for acute MI
  • medications activate body’s fibrinolytic system, dissolve clot, and restore coronary blood flow