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Obstetrics and Gynaecology > Medical Disorders in Pregnancy > Flashcards

Medical Disorders in Pregnancy Flashcards

1
Q

What is defined at Hypertension in pregnancy according to NICE?

A

140/90-159/109 mmHg

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2
Q

What is defined as severe HTN according to NICE?

A

> 160/110mm Hg

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3
Q

Define chronic HTN

A

HTN before 20 weeks in absence of hydatiform mole or persisting 6 weeks postpartum

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4
Q

Define pre-eclampsia

A

HTN after 20 weeks with one of proteinuria, maternal organ dysfunction or fetal growth restriction

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5
Q

Define eclampsia

A

Generalised tonic clonic seizure in women with pre-eclampsia if seizures not attributable to another cause

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6
Q

Give 4 risks of pre-eclampsia

A
  • 1st pregnancy
  • Fx (mother or sister)
  • Extremes of maternal age
  • Obesity
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7
Q

Give 5 symptoms of pre-eclampsia

A

Severe headache

Severe RUQ pain

Swelling of face/hands/feet

Visual disturbance

Vomiting

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8
Q

Give 5 signs of pre-eclampsia

A
  • HTN
  • Proteinuria
  • Hyperreflexia
  • Raised creatinine
  • Decreased platelets
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9
Q

What can be used as pre-eclampsia prevention in women with chronic HTN?

A

150mg aspirin from 12 weeks

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10
Q

What is the 1st line management for HTN if systolic 150-160?

A

Labetalol

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11
Q

in severe pre-eclampsia

(systolic>180) give 3 anti-hypertensives which can be used

A

o Oral/IV labetalol

o Oral nidedipine

o IV hydralazine

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12
Q

What can disrupted fluid balance in pre-eclampsia cause?

A

Too little: renal failure

Too much: pulmonary oedema

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13
Q

What is used to treat or prevent eclamptic seizures?

A

Magnesium sulphate

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14
Q

Give 3 maternal complications of pre-eclampsia

A
  • Placenta rupture
  • DIC
  • HELLP
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15
Q

Give 3 fetal complications of pre-eclampsia

A
  • IUGR
  • Pre-term delivery
  • Perinatal death
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16
Q

What is HELLP?

A

Haemolysis, elevated liver enzymes, low platelets

17
Q

Give 4 risk factors for gestational diabetes

A

BMI>30
Previous GD
Previous macrocosmic baby
FX diabetes

18
Q

What should be done if one risk factor of gestational diabetes is identified at booking?

A

Offer 2hr 75g OGTT at 24-28 weeks

19
Q

Give 3 pharmacological treatment options for gestational diabetes

A

Metformin
Glibenclamide
Insulin

20
Q

In cases of gestational diabetes, when should delivery occur?

A

No later than 40+6

21
Q

Give 3 effects of thyrotoxicosis on pregnancy

A

Miscarriage
IUGR
Preterm delivery

22
Q

Up until which point is fetal thyroxine obtained from the mother?

A

12 weeks

23
Q

Give 2 pharmacological treatments for hyperthyroidism in pregnancy

A

Carbimazole

Propanolol

24
Q

Give 3 effects of epilepsy on pregnancy

A
  • Seizure activity in 1st trimester
  • Decreased drug levels
  • Impaired sleep
25
Q

Can placental transmission occur during varicella zoster infection of the mother?

A

Yes

26
Q

At which level of viral RNA copies/ml would a normal vaginal delivery be considered?

A

<50 copies = normal delivery

27
Q

How should neonates be treated postnatally if the mother has HIV?

A

HIV post exposure prophylaxis within 4 hours of birth

28
Q

Give 3 situations in which anti-D would be required to be administered in a Rh negative mother

A
  • After management of ectopic
  • <12 weeks heavy vaginal bleed
  • <12 weeks medical/surgical management of miscarriage
29
Q

Which areas of the body does an atopic eruption of pregnancy effect?

A

Trunk and limbs

30
Q

Give 3 treatment options for atopic eruption of pregnancy

A

Emollient
Topical steroid
Antihistamine

31
Q

When and which areas of the body does polymorphic eruption of pregnancy effect

A

3rd trimester - postpartum

Lower abdomen and striae with UMBILICAL SPARING

32
Q

Give 3 treatment options for polymorphic eruption of pregnancy

A

Emollient
Topical corticosteroid
Sedating antihistamine

33
Q

Define pemphigoid gestationis

A

Rare condition of 2nd/3rd trimester caused by AI binding of IgG to basement membrane

34
Q

Give 3 skin features of pemphigoid gestationis

A

Urticarial lesions
Wheals and bullae
Umbilical area affected

35
Q

Give 3 management options for Pemphigoid Gestationis

A

Topical steroid
Systemic corticosteroid
REFER TO DERM AND OBSTETRICS

36
Q

Give 4 common skin changes which occur during pregnancy

A

Hyperpigmentation
Striae gravidarum
Angiomas
Greasier skin

Obstetrics and Gynaecology (10 decks)

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