Medicamentos Flashcards

1
Q

Rifampicina

A

Inhibición arn polímerasa dependiente adn

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2
Q

Isoniaziba

A

Inhibición de síntesis ácidos micolicos de pared celular

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3
Q

Etambutol

A

Inhibición enzima arabinosil-transferasa en la síntesis de pared celular

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4
Q

Pirazinamida

A

Destrucción de micobacterias que se replican en macrofagos

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5
Q

Mecanismo enoxoparins

A

Inhibición factor Xa

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6
Q

Dosis tóxica paracetamol

A

10 grms / 200 mg/kg

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7
Q

Metabólico tóxico paracetamol

A

N-acetil -para benzoquinonaimina NAPQUI

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8
Q

Metalobolito tóxico paracetamol en dosis terapeutica

A

Glutation

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9
Q

Fase 1 de intoxicación paracetamol

A

30 min - 24 hrs
Asintomático o gastrointestinal

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10
Q

Fase 2 intoxicación paracetamol

A

1-3 días
Dolor cuadrante sup derecho, síntomas gastrointestinales
+pruebas funcionamiento hepático, bilirrubinas

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11
Q

Fase 3 intoxicación paracetamol

A

2-4 dias
Falla hepática, deterioro meurologico
Edema cerebral
Falla renal

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12
Q

Fase 4 de intoxicación paracetamol

A

5 días- 2 semanas
Resolución falla hepática

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13
Q

Estudio de laboratorio intoxicación paracetamol

A

INR

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14
Q

Toxicidad en sangre paracetamol

A

> 200 ng/ml

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