Medications Flashcards by Shelby Burns

Ifosfamide (Ifex) disease sites

bladder, cervix, germ cell, H&N, lung, NHL, sarcomas

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Ifosfamide (Ifex) side effects

BLADDER TOXICITY, myelosuppression, N/V, anorexia, SIADH, neurotoxicity, alopecia

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Mechlorethamine (mustine, nitrogen mustard) disease sites

CLL, CML, HD, NHL, mycosis fungoides, breast, lung

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Mechlorethamine (mustine, nitrogen mustard) side effects

Myelosuppression, N/V, hyperuricemia, pain/inflammation @ injection site, alopecia

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Melphalan (Alkeran) disease sites

breast, ovarian, MM, HCT, polycythemia vera, neuroblastoma

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Melphalan (Alkeran) side effects

myelosuppression, N/V/C, mucositis, hypersensitivity infusion reaction

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Oxaliplatin (Eloxatin) disease sites

Colorectal, pancreatic

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Oxaliplatin (Eloxatin) side effects

myelosuppression, N/V/D, neurotoxocity (sensitivity to cold), hepatic toxicity

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Temozolomide (Temodal) disease sites

astrocytomas, glioblastoma

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Temozolomide (Temodal) side effects

myelosuppression, N/V/C, fatigue, headache, hepatic toxicity, photosensitivity, rash

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Thiotepa (Thioplex) disease sites

bladder, breast, ovarian, HD, NHL

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Thiotepa (Thioplex) side effects

myelosuppression, N/V, mucositis, renal toxicity, skin changes

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Antimetabolites

interfere with DNA synthesis by acting as false metabolites ; incorporated into the DNA strand or block essential enzymes

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Azaxcitidine (Vidaza) disease sites

CML, myelodysplastic syndrome (MDS)

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Azaxcitidine (Vidaza) side effects

myelosuppression, N/V/C/D, fatigue, hypokalemia, renal toxocity

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Capecitabine (Xeloda) disease sites

colon, esophageal, pancreatic, rectal, (metastatic) breast

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Capecitabine (Xeloda) side effects

myelosuppression, N/V/D, fatigue, increased bilirubin, hand and foot syndrome (needs heavy lotion for rash)

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Cytarabine (ARA-C) disease sites

ALL, APL, AML, CML, HNL

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Cytarabine (ARA-C) side effects

myelosuppression, N/V > 1mg/m2, mucositis, anorexia, acute pancreatitis, neurotoxicity (lethargy, confusion), hepatic toxicity, pulmonary toxicity, conjunctivitis, keratitis

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Fludarabine (Fludara) disease sites

CLL, HNL, acute leukemias

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Fludarabine (Fludara) side effects

myelosuppression, N/V/D, neurotoxicity, rash

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Fluorouracil (5FU) disease sites

breast, colon, rectal, cervical, GI tract, H&N, pancreatic, ovarian, stomach, unknown primary, hepatobiliary, neuroendocrine, thymic

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Fluorouracil (5FU) side effects

myelosuppression, N/V/D, mucositis, hand and foot syndrome, cardiac toxicity, photosensitivity, dysgeusia

Nutrient of interest: B6 (hand foot syndrome)

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Gemcitabine (Gemzar) disease sites

bladder, breast, lung, ovarian, pancreatic, HNL, sarcoma

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Gemcitabine (Gemzar) side effects

myelosuppression, N/V, pulmonary toxicity, rash, FLU-LIKE SYMPTOMS

Hydroxyurea (Hydrea) disease sites

CML, blood disorders, H&N, ovarian

Hydroxyurea (Hydrea) side effects

myelosuppression, N/V/D, mucositis, darkening/thickening of the nails

Mercaptopurine (6-MP) disease sites

ALL, APL, lymphoma, ulcerative colitis, Crohn's disease

Mercaptopurine (6-MP) side effects

myelosuppression, N/V/D, mucositis, hepatic toxicity, hyperuricemia

Methotrexate (MTX) disease sites

bladder, breast, H&N, HNL, ALL, osteosarcoma, rheumatoid arthritis

Methotrexate (MTX) side effects

myelosuppression, nausea, mucositis, oral + GI ulcerations, renal toxicity, hepatic toxicity, photosensitivity

Methotrexate (MTX) usually requires what supplements?

folic acid and B12 to reduce side effects

Pemetrexed (Alimta) disease sites

mesothelioma, lung

Pemetrexed (Alimta) side effects

myelosuppression, N/V/D, fatigue, rash Nutrients of interest: folic acid, vit B12

Pemetrexed (Alimta) usually requires what supplements?

folic acid and B12 to reduce side effects

Thioguanine (6-TG) disease sites

AML, CML

Thioguanine (6-TG) side effects

myelosuppression, N/V/D, mucositis, hepatic toxicity, renal toxicity, rash

Bleomycin (Blenoxane) disease sites

HD, HNL, H&N, SCC of the skin, cervical, vulva, testes, melanoma, malignant pleural effusions

Bleomycin (Blenoxane) side effects

PULMONARY TOXICITY, renal toxicity, hyperpigmentation, skin/nail changes, hypersensitivity infusion reaction

Dactinomycin (Actinomycin D) disease sites

Ewing sarcoma, rhabdomyosarcoma, Wilms tumor, testicular

Dactinomycin (Actinomycin D) side effects

myelosuppression, N/VD, mucositis, anorexia, alopecia

Mitomycin-C (Mutamycin) disease sites

anal, bladder, breast, esophageal, H&N, lung, pancreatic, stomach

Mitomycin-C (Mutamycin) side effects

myelosuppression, N/V/D, mucositis, anorexia, pulmonary toxicity, renal toxicity, alopecia

Cisplatin disease sites

Lung Bladder Ovarian Testicular H&N Esophageal Neuroblastoma

Cisplatin side effects

N/V, increased fluid needs, check renal function/electrolytes, SIADH, B/C/D, dyusgeusia, HLD/CVD risk May cause hypoalbuminemia Milk Thistle may benefit Tumeric may benefit (fatty foods, black pepper) Omega 3 may benefit

Carboplatin disease sites

Ovarian Fallopian tube NSCLC

Carboplatin side effects

N/V, renal toxicity

Abraxane (Paclitaxel) disease sites

Breast Lung Pancreatic Second line breast

Abraxane (Paclitaxel) side effects

N/V/D, mucositis, LE edema, elevated LFT’s

Adriamycin (Doxorubicin) disease sites

Burkitt’s Lymphoma Hodgin’s Lymphoma Wilm’s tumor Acute Lymphoid Leukemia Acute Myeloid Leukemia

Adriamycin (Doxorubicin) side effects

N/V/D, loss of appetite, mucositis CoQ10 limits renal/cardiac toxicity Theanine may benefit Omega 3 may benefit

Alemtuzumab (Campath) disease sites

Leukemia

Alemtuzumab (Campath) side effects

hypotension, anemia Used for B cell lymphoma

Anastrozole (Arimidex) disease sites

Breast (post menopausal)

Anastrozole (Arimidex) side effects

N/V/C/D, hot flashes, thromboembolic issues

Aromasin (Exemestane) disease sites

Breast (post menopausal)

Aromasin (Exemestane) side effects

hot flashes, thromboembolic issues, N/V

Avastin (Bevacizumab) disease sites

Cervical Glioblastoma Liver Ovarian Fallopian tube

Avastin (Bevacizumab) side effects

N/V/C/D, mucositis

Cetuximab (Erbitux) disease sites

Colorectal H&N

Cetuximab (Erbitux) side effects

Causes: N/C/D, loss of appetite, decreased Mg, cardiac/respiratory distress Nutrients of interest: Mg/Ca

Carmustine (BiCNU) disease sites

Multiple Myeloma Brain Hodgkin’s disease Non-Hodgkin’s Lymphoma

Carmustine (BiCNU) side effects

N/V

Cyclophosphamide (Cytoxan) disease sites

Multiple Myeloma Leukemia Hodgkin’s Lymphoma Burkitt’s Lymphoma

Cyclophosphamide (Cytoxan) side effects

N/V < 1500 mg/m2, SIADH

Dacarbazine (DTIC-Dome) disease sites

Skin – Melanoma (metastatic) Hodgkin’s disease

Dacarbazine (DTIC-Dome) side effects

N/V, flu like s/s

Daunorubicin (Cerubidine) disease sites

Leukemia

Daunorubicin (Cerubidine) side effects

N/V

Epirubicin (Ellence) disease sites

Breast

Epirubicin (Ellence) side effects

N/V

Etoposide (Toposar) disease sites

Lung

Etoposide (Toposar) side effects

May enhance Coumadin N/V, hypersensitivity

Erythropoietin

A hormone that your kidneys naturally make to stimulate the production of RBC May be given to patients for fatigue

Faslodex (Fulvestrant) disease sites

Breast

Faslodex (Fulvestrant) side effects

N/V, hot flashes

Femara (Letozole) disease sites

Breast

Femara (Letozole) side effects

hot flashes, thromboembolic issues

Herceptin (Traztuzumab) disease sites

Breast Stomach Esophageal

Herceptin (Traztuzumab) side effects

N/V/D, flu like s/s, anemia Oleic Acid may help – found in avocado, nuts/seeds, oils

Idarubicin (Idamycin) disease sites

Leukemia

Idarubicin (Idamycin) side effects

N/V Theanine may benefit

Irinotecan (Camptosar) disease sites

Colorectal

Irinotecan (Camptosar)

N/V/D, loss of appetite Omega 3 may benefit

Kadcyla (Ado-trastuzumab emtansine) disease sites

Breast

Kadcyla (Ado-trastuzumab emtansine) side effects

Toxic to cardiac, liver, lung, causes constipation, thrombocytopenia

Lupron (leuprolide) disease sites

Prostate

Lupron (leuprolide) side effects

N/V/C/D

Mechlorethamine (Valchlor) disease sites

Lymphoma

Mechlorethamine (Valchlor) side effects

N/V Used on the skin

Mitomycin (Mutamycin) disease sites

Stomach Pancreatic

Mitomycin (Mutamycin) side effects

N/V/D, loss of appetite, mucositis, SOB, renal/lung toxicity, discolored urine

Megace side effects

wt gain, fluid retention

Navelbine (Vinoelbine) disease sites

NSCLC

Navelbine (Vinoelbine) side effects

N/V/C, loss of appetite

Oncovin (Vincristine) disease sites

Lymphoma Wilm’s tumor

Oncovin (Vincristine) side effects

constipation, renal toxicity

Oxaliplatin (Eloxatin) disease sites

Colorectal

Oxaliplatin (Eloxatin) side effects

cold sensitivity, N/V/D Nutrients of interest: Mg/Ca

Panitumumab (Vectibix) disease sites

Colorectal

Panitumumab (Vectibix) Nutrient of interest

Paclitaxel (Taxol) disease sites

Breast Ovarian Esophageal Lung Cervical Pancreatic

Paclitaxel (Taxol) side effects

N/V/D, mucositis, decreased Mg/K+/vit D, fatigue May cause hypoalbuminemia Omega 3 may benefit Selenium may benefit

Pertuzumab (Perjeta) disease sites

Breast

Pertuzumab (Perjeta) side effects

N/V/C/D, mucositis

Sorafenib (Nexavar) disease sites

Kidney Liver Thyroid

Sorafenib (Nexavar) side effects

N/V/D, loss of appetite

Tacrolimus (Prograf) disease sites

Kidney Heart Liver Lung (transplants)

Tacrolimus (Prograf) nutrients of interest

Mg/K+

Taxotere (Docetaxel) disease sites

Breast Lung Prostate Stomach H&N

Taxotere (Docetaxel) side effects

N/V, fluid retention

Tamoxifen (Nolvadex, Soltamox) disease sites

Breast

Tamoxifen (Nolvadex, Soltamox) side effects

hot flashes, thromboembolic issues, menstrual s/s, fluid retention

Topotecan (Hycamtin) disease sites

Ovarian Lung Cervical

Topotecan (Hycamtin) side effects

N/C/D, loss of appetite, mucositis

Velcade (Bortezomib) disease sites

Multiple Myeloma Mantle Cell Lymphoma

Avoid what with Velcade (Bortezomib)

Avoid green tea

Vincristine (Oncovin) disease sites

Lymphoma Wilm’s tumor

Vincristine (Oncovin) side effects

constipation Omega 3 may benefit

Zoladex (Goserelin) disease sites

Prostate Breast

Zoladex (Goserelin) side effects

N/V/C

Zometa (Zoledronic acid) nutrients of interest

Ca/Vit D Used to treat hypercalcemia that may occur with cancer

Busulfan (Busulfex) disease sites

Heme

Busulfan (Busulfex) side effects

Hepatic toxicity, pulmonary toxicity (get pulm tests before)

Medications Flashcards

(124 cards)