Medications

Question 1

Haloperidol(Type, MOA, Mx, S/E)

Answer 1

Typical Antipsychotic - high potency
MOA: Dopamine Antagonist
Mx: Schizophrenia
S/E: Extrapyramidal (Dystonia, muscle rigidity, akathisia, parkinsonism); Hypotensionaka Haldol

Question 2

Chlorpromazine(Type, MOA, Mx, S/E)

Answer 2

Typical Antipsychotic - low potency
MOA: Dopamine Antagonist
Mx: Schizophrenia
S/E: Histaminic (sedation); Alpha adrenergic (orhostatic hypotension); Anticholinergic (Dry Mouth)aka Thorazine

Question 3

Fluphenazine(Type, MOA, Mx, S/E)

Answer 3

Typical Antipsychotic - high potency
MOA: Dopamine Antagonist
Mx: Schizophrenia
S/E: Extrapyramidal (Dystonia, muscle rigidity, akathisia, parkinsonism); Hypotensionaka Proxlixin

Question 4

Aripiprazole(Type, MOA, Mx, S/E)

Answer 4

Atypical Antipsychotic
MOA: Partial agonist of D2 receptor and some 5-HT receptors (1A,2C). Antagonises some 5-HT receptors (2A, 7)
Mx: Schizophrenia
S/E: Weight Gain; headache; agitation;aka Abilify

Question 5

Risperidone(Type, MOA, Mx, S/E)

Answer 5

Atypical Antipsychotic
MOA: Dopamine Antagonist plus Anti-serotonergic/adrenergic/histaminergic
Mx: Schizophrenia; Schizoaffective Disorder; mixed/manic bipolar state
S/E: Hyperprolactinaemia; Weight Gain; Othersaka Risperdal

Question 6

Clozapine(Type, MOA, Mx, S/E)

Answer 6

Atypical Antipsychotic
MOA: Dopamine Antagonist plus Anti-serotonergic/adrenergic/histaminergic
Mx: Schizophrenia
S/E: Agranulocytosis; Cardiac Toxicity; GI Hypomotility; Hypersalivation (M4 agonist); Weight Gain;aka Clozaril

Question 7

Olanzopine(Type, MOA, Mx, S/E)

Answer 7

Atypical Antipsychotic - Thienobenzodiazepine
MOA: Dopamine Antagonist plus Serotonin Antagonist
Mx: Schizophrenia
S/E: Weight Gain; Paradoxical Reactions (personality/thought/hallucinations); Othersaka Zyprexa

Question 8

Citalopram(Type, MOA, Mx, S/E)

Answer 8

Antidepressant
MOA: Selective Serotonin Reuptake Inhibitor
Mx: Depression; Panic Disorder
S/E: Sexual Dysfunction (Less libido, anorgasmia, ejaculatory anhedonia); Antihistaminergic (sedation); Weight Gain; Suicideaka Celexa, Cipramil

Question 9

Fluoxetine(Type, MOA, Mx, S/E, C/Is)

Answer 9

Antidepressant
MOA: Selective Serotonin Reuptake InhibitorMx: Depression; OCD; Panic Disorder
S/E: Sexual Dysfunction (Less libido, anorgasmia, ejaculatory anhedonia); Suicide
C/Is: Prior use of MAOIs within two weeks otherwise risk serotonin syndrome

Question 10

Sertraline(Type, MOA, Mx, S/E)

Answer 10

Antidepressant
MOA: Selective Serotonin Reuptake InhibitorMx: Depression; OCD; Panic Disorder;
S/E: Sexual Dysfunction (Less libido, anorgasmia, ejaculatory anhedonia); Suicideaka Zoloft

Question 11

Isocarboxazid(Type, MOA, Mx, S/E)

Answer 11

Antidepressant - Hydrazine class
MOA: Non-selective, irreversible MAOI 
Mx: Depression; Anxiety
S/E: Headaches; Jaundice; Weight Gain; Orthostatic Hypotension; Tremors; Othersaka Marplan

Question 12

Moclobemide(Type, MOA, Mx, S/E)

Answer 12

Antidepressant - Benzamide
MOA: Selective, Reversible inhibitor of MAO-A (RIMA) leading to increased noradrenaline, dopamine and serotonin.
Mx: Depression; AnxietyS/E: Insomnia; Headache; Dizzinessaka Amira

Question 13

Selegiline(Type, MOA, Mx, S/E)

Answer 13

Antidepressant - Phenethylamines
MOA: Selective, Reversible inhibitor of MAO-B (larger doses it becomes MAO-A selective too)
Mx: Depression; Parkinson’s Disease (enhances efficacy of levodopa)
S/E: Dizziness; Dry Mouth; Insomniaaka Selgene

Question 14

Amitriptyline(Type, MOA, Mx, S/E, C/Is)

Answer 14

Tricyclic Antidepressant
MOA: Serotonin-norepinephrine reuptake inhibitorMx: Depression
S/E: Dizziness; Dry Mouth; Insomnia; Delirium; Confusion; Anxiety; Agitation
C/Is: History of MI/CHF/arrhythmias; Mania; Liver disease aka Amitrip

Question 15

Reboxetine(Type, MOA, Mx, S/E, C/Is)

Answer 15

Antidepressant
MOA: Norepinephrine reuptake inhibitor
Mx: Depression
S/E: Nausea; Insomnia; insomnia; dizziness; dry mouth
C/Is: MAOIs; narrow angle glaucomaaka Davedax

Question 16

Duloxetine(Type, MOA, Mx, S/E, C/Is)

Answer 16

Antidepressant
MOA: Serotonin-norepinephrine reuptake inhibitor
Mx: Depression; GAD
S/E: Nausea; Somnolence; insomnia; dizziness; dry mouth
C/Is: MAOIs; narrow angle glaucomaaka Cymbalta

Question 17

Lithium(Type, MOA, Mx, S/E, C/Is)

Answer 17

Mood-stabiliser
MOA: Serotonin-norepinephrine reuptake inhibitor
Mx: Bipolar
S/E: Tremor; Polydipsia; Polyuria; Weight Gain; Thyrotoxicity; Nephrotoxicity; Leukocytosis
C/Is: Pregnancyaka Camcolit

Question 18

Valproate(Type, MOA, Mx, S/E, C/Is)

Answer 18

Mood-stabiliser + Anti-convulsant
MOA: Inhibits GABA breakdown, Na channel blocker,
Mx: Bipolar; Epilepsy
S/E: Nausea; Vomiting; Tremors; Sedation; Weight Gain; Transient hair loss; Thrombocytopenia; Hepatotoxicity; Pancreatitis
C/Is: Pregnancyaka Epilim

Question 19

Carbamezapine(Type, MOA, Mx, S/E, C/Is)

Answer 19

Mood-stabiliser + Anti-convulsant
MOA: GABA receptor agonist, Na channel blocker,
Mx: Bipolar; Epilepsy
S/E: Drowsiness; dizziness; ataxia; diplopia; agranulocytosis; hyponatraemia
C/Is: Pregnancyaka Tegretol

Question 20

Diazepam(Type, MOA, Mx, S/E, C/Is)

Answer 20

Benzodiazepine
MOA: positive allosteric modulator of GABA-A receptors
Mx: Anxiety; Panic; Acute Alcohol Withdrawal; Anti-convulsion
S/E: Ataxia; Drowsiness; Confusion; Amnesia; Paradoxical (nervousness, irritability, etc.)
C/Is: Pregnancyaka Valium

Question 21

Zopiclone (Type, MOA, Mx, S/E, C/Is)

Answer 21

Non-benzodiazepine hypnotic/anxiolytic
MOA: Bind GABA-A receptors and enhance effect of GABA
Mx: Short-term treatment for insomnia
S/E: Tolerance, dependence, addiction. Elderley balance issues, taste disturbances, dry mouth.
C/Is: Vehicle drivers

Question 22

Gabapentin (Type, MOA, Mx, S/E)

Answer 22

Anticonvulsant
MOA: Not fully described
Mx: Seizures; Pain; anxiety
S/E: dizziness; fatigue; weight gain; suicide

Question 23

Topiramate (Type, MOA, Mx, S/E)

Answer 23

Anticonvulsant
MOA: Inhibition of high-voltage-gated Ca channels
Mx: Epilepsy; migraine
S/E: N+V; diarrhoea; dizziness; paraesthesia