Medications for Surgery Floor Flashcards

(104 cards)

1
Q

risk of Tylenol 3s, Percocet, Oxycocet, Tramacet

A

sedation; nausea; constipation; tolerance

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2
Q

risk of amoxicillin, clavulin (amoxicillin-clavulanate), ampicillin

A

allergic reactions, diarrhea, antibiotic resistance

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3
Q

tramacet (acetaminophen-tramadol) clinical comments

A

Might be less constipating than Tylenol 3s and less euphoric than Percocet. Can rarely cause seizures in therapeutic doses.

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4
Q

amoxicillin clinical comments

A

use IV only; used w/ gentamicin for synergy

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5
Q

bisacodyl (dulcolax) benefit

A

treats constipation by stimulating gut motility

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6
Q

bisacodyl (dulcolax) risk

A

chronic use can lead to laxative dependence

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7
Q

bisacodyl (dulcolax) clinical comments

A

used for bowel routines in patients on opioids

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8
Q

Bupivacaine (macaine) benefit

A

relieves moderate to severe pain when used alone or with opioids; may be used topically prior to dressing changes to relieve pain

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9
Q

Bupivacaine risk

A

excessive numbing epidurally; stinging on topical application; allergic reactions

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10
Q

Bupivacaine (marcaine) clinical comments

A

may be used epidurally if patient develops excessive sedation; limited evidence of benefit in topical applications

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11
Q

cadacara

A

same as bisacodyl

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12
Q

cefazolin (ancel) benefit

A

cures many gram positive and gram negative infections (antibiotic)

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13
Q

cefazolin (ancel) risk

A

same as amoxicillin (so allergic reactions and diarrhea)

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14
Q

cefazolin clinical comments

A

may cross-react in patients allergic to penicillins (2-10%); used w/ gentamicin for synergy

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15
Q

cefotaxime benefit

A

cures many gram positive and gram negative infections

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16
Q

cefotaxime risks

A

same as amoxicillin (allergic & diarrhea)

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17
Q

cefotaxime clinical comments

A

alternative to ciprofloxacin

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18
Q

ciprofloxacin (cipro) benefits

A

cures some gram positive and many gram negative infections

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19
Q

ciprofloxacin risks

A

allergic; diarrhea, restless

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20
Q

ciprofloxacine clinical comments

A

can cause seizures in patients with history of seizures; IV and PO doses not equivalent in mg:mg

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21
Q

clindamycin benefit

A

cures some gram positive and many anaerobic infections

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22
Q

clindamycin risk

A

c.difficile diarrhea; less effective than metronidazole

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23
Q

clindamycin clinical comments

A

alternative to metronidazole

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24
Q

dimenhydrinate (gravel) benefit

A

treats N&V; especially associated w/ motion sickness

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25
dimenhydrinate risk
sedation; limited anti-emetic effect
26
diphenoxylate-atropine (Lomotil) benefit
treats diarrhea by slowing passage of food through the gut
27
diphenoxylate-atropine (lomotil) risk
sedation; combine with atropine wot prevent abuse
28
diphenoxylate-atropine (lomotil) clinical comments
can be used in combination with other anti-diarrhea to reduce output but not if C.difficile positive
29
docusate (Colace) benefit
prevents & treats constipation (hard stools), especially associated with opioid use
30
domperidone benefit
facilitates stomach emptying and movement of food through the small bowel
31
domperidone clinical comments
not effective for lower GI motility problems; doesn't readily cross BBB to the extent metoclopramide does, so causes less CNS effects (good for patients with Parkinsons
32
electrolyte lavage solution (PegLyte) benefit
evacuates contents of bowels prior to surgery via an osmotic effect
33
PegLyte risk
large volume of bad tasting solution
34
erythromycin benefit
same as domperidone via different mechanism; also treats gram positive and atypical bacterial infections
35
erythromycin risk
not effective for lower GI motility problems; important interactions with numerous medications
36
fluconazole benefit
treats many fungal infections
37
fluconazole clinical comments
oral and IV doses equivalent on a mg:mg basis
38
gentamicin benefit
same as ciprofloxacin
39
gentamicin risk
nephrotoxic; ototoxic; IV only; drug levels for prolonged (> 5 days) therapy
40
gentamicin clinical comments
drug level = 10-15 minutes before 3rd dose (trough) and 10-15 minutes after 3rd dose (peak)
41
hydrocortisone (solu-cortef) benefit
prevents adrenal crisis in patients on long term steroid therapy who require surgery
42
hydrocortisone (solu-cortef) risk
short-acting; hyperglycemia, delayed wound healing, infection
43
hydromorphone (dilaudid) risk
sedation; pruritus; hallucinations
44
hydromorphone clinical comments
hydromorph 1mg PO = morphine 5 mg PO
45
hydromorphone CR clinical comments
may open capsules, but do not crush, to give down tubes
46
Imipenem-cilastin (primaxin) benefit
same as amoxicillin-clavulonate
47
Imipenem-cilastin (primaxin) clinical comments
can react with penicillins (10-50% risk); seizures at high doses
48
ketorolac (toradol) risk
GI bleeding, nephrotoxicity, ASA cross-reaction can occur
49
lansoprazole DR (Prevacid) benefits
prevents/treats symptoms of GERD
50
lansoprazole DR (Prevacid) risks
diarrhea
51
loperamide (Imodium) benefit
same as diphenoxylate-atropine (treats diarrhea)
52
loperamide (Imodium) risk
less risk than diphenoxylate-atropine (Lomotil)
53
loperamide (Imodium) clinical comments
often confused with diphenoxylate-atropine (lomotil); doesn't readily cross the BBB; not to use if C.diff +
54
lorazepam (ativan) benefits
prevents symptoms of alcohol withdrawal; also used to treat insomnia and relieve anxiety
55
lorazepam risks
withdrawal; amnesia; sedation; habituation
56
Meropenem (Merrem) benefit
same as imipenem-cilastin (antibiotic)
57
Metoclopramide (maxeran) benefit
same as domperidone (facilitates stomach emptying )
58
Metoclopramide (maxeran) clinical comments
avoid in patients with Parkinsonism and seizure disorders
59
Metronidazole (Flagyl) benefit
treats many anaerobic infections
60
Metronidazole (Flagyl) risk
metallic taste; allergic reactions
61
Metronidazole (Flagyl) clinical comments
used Q12H for surgery patients but Q8H for C.diff; oral preferred but IV effective for C. diff
62
Meperidine (demerol) benefit
same as hydromorph
63
Meperidine (demerol) risk
short acting (Q3H dosing may be required); toxic metabolite
64
Morphine (Satex) benefit
same as hydromorphine
65
Morphine (Satex) risk
same as hydromorphone with a toxic metabolite
66
Morphine clinical comments
gold standard opioid which others are compared against
67
Morphine CR (MS Contin) benefit
same as hydromorphone
68
Morphine CR (MS Contin) risk
same as morphine
69
Morphine CR (MS Contin) clinical comments
equivalent to morphine ER but can not be given via tubes
70
Morphine ER (M-Eslon) benefit
same as hydromorph
71
Morphine ER (M-Eslon) risk
same as hydromoprhone
72
Morphine ER (M-Eslon) clinical comments
capsules may be opened but not crushed to give via tubes
73
Nystatin benefit
treats some fungal infections, primarily candida (thrush) of the oral cavity; also may be used around ostomy sites
74
Nystatin risk
not absorbed orally so minimal toxicity; not effective against all fungi
75
Nystatin clinical comments
should be given after meals to maximize contact time with mucosa
76
Octreotide (Sandostatin) benefit
prevents complications (fistula, abscess formation) after pancreatic surgery; also decreases diarrhea from some kinds of GI tumours; also reduces ostomy output after GI surgery
77
Octreotide (Sandostatin) risk
may be blunt GI mucosal adaptation if given early after major bowel resection; long term use may increase risk of gallstone formation; hyperglycemia
78
Octreotide (Sandostatin) clinical comments
preferred route is SQ as IV has a shorter duration of action
79
Octreotide LAR (Sandostatin LAR) benefit
used when longer-term therapy with octreotide is anticipated
80
Octreotide LAR clinical comments
for IM use only - given once monthly (onset = 2 weeks); overlap recommended)
81
Ondansetron (Zofran) benefit
prevents nausea and vomiting, especially postoperatively
82
Ondansetron (zofran) risk
better for acute N&V (<48hrs) than delayed type N&V
83
Pantaprazole (Pantoloc) benefit
same as lansoprazole; pantoprazole iv infusion used to treat upper GI bleeding
84
Pantaprazole clinical comments
not indicated for patients already on ranitidine
85
Prochlorperazine (stemetil) benefit
treats nausea/vomiting, especially associated with medication use
86
Prochlorperazine (stemetil) risk
dystonic reactions (severe neck stiffness); extrapyramidal symptoms, especially if used with metoclopramide
87
Prochlorperazine (stemetil) clinical comments
may be used with other anti-emetics (avoid metoclopramide) to control postoperative nausea and vomiting
88
Ranitidine (Zantac) benefit
same as lansoprazole except less effective
89
Ranitidine (zantac) risk
confusion in patients with renal impairment
90
senna (senokot) benefit
same as bisacodyl (constipation)
91
sodium phosphate (fleet) benefit
same as electrolyte lavage solution; also used as an enema for constipation/obstipation
92
sodium phosphate (fleet) risk
two-dose oral bowel cleansing regimens associated with electrolyte abnormalities
93
sodium phosphate (fleet) clinical comments
more electrolyte disturbances than with electrolyte lavage solution
94
sulfamethoxazole-trimethoprim (septra) benefit
same as cefazolin (antibiotic)
95
Sulfamethoxazole-trimethoprim (Septra) risk
nausea, allergic reactions, hyperkalemia
96
Total Parenteral Nutrition (TPN) benefit
provides nutritional needs when the gut is being rested or is unavailable secondary to disease/surgery
97
TPN risk
hyperglycemia, hyperlipidemia, electrolyte disturbances, liver toxicity, infections
98
TPN clinical comments
slow initiation is recommended in malnourished patients "re-feeding syndrome"; taper on discontinuation; D10% may be used if TPN unavailable; avoid peripheral TPN
99
warfarin (coumadin) benefit
treats clots by preventing their growth and forming thrombi
100
warfarin (coumadin) risk
bleeding, hair loss, lab monitoring
101
warfarin (coumadin) clinical comments
vitamin K reverses effect; may use vitamin K injection for oral doses; high doses (>5mg) of vitamin K can cause warfarin resistance
102
zopiclone (imovane) benefit
insomnia
103
zopiclone (imovane) risks
same as lorazepam
104
zopiclone (imovane) clinical comments
alternative sedation if benzos ineffective