Medicine Flashcards

1
Q

Auer Rods

A

AML

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2
Q

Philadelphia chromosome

A

CML

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3
Q

most common leukaemia in children

A

ALL

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4
Q

70 y/o, weight loss, painless lymphadenopathy, lymphocytosis

A

CLL. Can transform to Richter’s syndrome.

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5
Q

60 y/o, abdo pain, massive splenomegaly, weight loss/tired/night sweats, WCC RAISED

A

CML

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6
Q

Child: easy bruising, infections, hepatosplenomegaly, pancytopenia

A

ALL

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7
Q

smear cells

A

CLL

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8
Q

teardrop cells

A

myelofibrosis

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9
Q

Pt has blood transfusion –> 30min later has fever, hypotensive, red coloured urine. What rxn is going on?

A

Immediate haemolytic transfusion rxn

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10
Q

fever, muscle pain, loss appetite, N&V. slow pulse & high temp. Dx?

A

Yellow fever

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11
Q

alpha feta protein: tumour marker for ?

A

hepatocellular carcinoma (liver ca)

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12
Q

4 y/o, lymphadenopathy, febrile, sore throat, palpable liver edge. Dx?

A

ALL

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13
Q

10 y/o: marble like swellings over armpits & neck. Not painful. Dx?

A

non Hodgkin’s lymphoma

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14
Q

1st line Tx for absence seizure

A

sodium valproate

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15
Q

Is PSC associated w UC or Crohn’s?

A

UC

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16
Q

45 y/o, jaundice, xanthelasma, skin excoriation. Raised ALP, slightly raised AST, ALT. +ve for AMA M2 abs. ?Dx

A

PBC

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17
Q

causative agent for travellers’ diarrhoea?

A

E coli

18
Q

What is pellagra and what are its symptoms?

A

Lack of niacin.
Dementia, diarrhoea, dermatitis

19
Q

45 y/o - palppitations, dizziness, SOB. Sx associated w change in position. S1 pansystolic mumur @ apex. Dx?

A

atrial myxoma

20
Q

65 y/o. PMH: DM, IHD. Has soft early diastolic murmur best heard at L parasternal edge on expiration. ?dx
Collapsiing pulse/wide pulse pressure.

A

aortic regurgitation

21
Q

14 y/o boy, reports: clumsy in morning spilling cereal, daydreaming, sometimes uncontrollably jerky. Dx?

A

Janz syndrome (juvenile myoclonic epilepsy)
generalised seizure on waking, daytime absences, myoclonic

22
Q

STEMI treatment. No PCI available - what is the medical mx?

A

ticagrelor + aspirin.
or clopidogrel + aspirin or clopi alone - if high risk bleeding

23
Q

STEMi treatment. Pt having PCI - what to give?

A

prasugrel + aspirin.

24
Q

STEMI treatment. Pt having PCI, BUT has had prev stroke. What to give?

A

clopidogrel + aspirin.
Prasugrel is contraindicated in prev stroke

25
Q

skin condition: ankles/elbows, associated w coeliac disease?

A

dermatitis herptiformis

26
Q

ObG: Gestational sac >25mm with no fetal pole = what kind of miscarriage?

A

missed miscarriage

27
Q

35 y/o M - aki, haemoptysis, fever. Anti- GBM abs. Dx?

A

Good pasture’s

28
Q

abs associated w antiphospholipid syndrome?

A

anti-cardiolipin

29
Q

what is erysipelas? RF? how to treat?

A

superficial skin infection. DM. Penicillin.

30
Q

when to transfuse platelets?

A

platelets <50

31
Q

When to give FFP?

A

when PT is >1.5x normal

32
Q

WHen to give prothrombin complex concentrate?

A

when patient has been on warfarin and there is no time to reverse it

33
Q

Greek man, Heinz bodies, +ve Beutler test = dx?

A

G6PD

34
Q

what are heinz bodies? what might it indicate?

A

denatured Hb - indicative of haemolysis
e.g. G6PD, thalassaemia, haemolytic anaemia

35
Q

Pt: DM, sudden painless loss of vision in L eye. Pale, swollen optic disc. Dx?

A

AION (anterior ischaemic optic neuropathy)

36
Q

what abx can cause achilles tendionpathy?

A

fluoruquinolones - e.g. ciprofloxacin

37
Q

20 yr old - anal pain on and after defecation. blood on wiping. dx?

A

anal fissure

38
Q

GU clinic: male has itchy penis, no discharge. Doesn’t use condoms. Tx?
GU clinicl: male has purulent discharge, dysuria. Dx?

A

Chlamydia –> azithromycin IM or doxy BD
gonorrhoea –> azithromycin + cefotaxime

39
Q

How is SCLC often treated?

A

chemo, radio
not as effective in NSCLC

40
Q

what is the treatment for polycythaemia vera?

A

asymptomatic: venesection, aspirin
symptomatic: immunosuppression