Medicines and drugs Flashcards

(37 cards)

1
Q

drug

A

a chemical that alters sensory sensations, mood, or activity state

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2
Q

methods of administering drugs

A

mouth, inhalation. anus, injection, skin

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3
Q

thalidomide

A

morning sickness, birth defects

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4
Q

lethal dose

A

required to kill 50% of pop

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5
Q

effective dose

A

bring noticeable effect in 50% of pop

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6
Q

risk to benefit ratio

A

severity of complaint depends on. if treatment for life threatening disease , high risl from side effect is accepted

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6
Q

tolerance

A

body adapts to actio of drug, needs larger dose. if dise increases, risk of dependence and reaching lethal dose

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7
Q

indigestion

A

discomfort caused by excess acid which damages stomach lining

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8
Q

antacids

A

combat stomach acid

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9
Q

antifoaming agents and alginates

A

prevent heartburn and flautulence. dimethicone

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10
Q

apririn

A

prevents prostaglandin, fever, pain
side effects of stomach ulsers
children- liver and brain disorder
lower blood ph

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10
Q

depressants

A

slow down nervous sytem. sleepiness

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10
Q

ethanol

A

ste- relax, judgement impaired

lte- liver disease, high blood pressure, birth defects

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10
Q

synergistic effects

A

ethanol enhances other drugs

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11
Q

breathalyser

A

acidified dichromate turns green when reduced by alcohol

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12
Q

stimulants

A

increase state of mental alertness

12
Q

amphetamines

A

fight or flight. increase heart rate, decrease appetite, emotional instability.

13
Q

designer drugs

A

E, relieves parkinsons disease, sensitivity, hallucinations

13
Q

caffeine

A

alertness concentration. alkaloid- choco

14
Q

nicotine

A

w- insomnia, depression

heart disease, cancer, birth defects

14
Q

antibacterial

A

prevent growth of bacteria

15
Q

penicilin

A

cure sore throat, TB, . passed in meat

16
Q

broad spectrum antibiotics

A

an antibiotic with activity against a wide range of disease-causing bacteria; it also acts against both Gram-positive and Gram-negative bacteria.

17
Q

mechanism of antibiotics

A

prevent from makingnormal cell walls

inside bacteria

18
virus
no nucleus, not cells, reproduce inside cells of living creatures
19
antivirals
cold, influenza, mumps. alter cells genetic material so virus cant use it to multiply .- acyclovir prevent new virus from leaving cell prblm because always mutating- HIV
20
AIDS
virus invades Tcells, cant fight infection AZT- clog active site
20
chirality
asymmetric/ chiral atoms. r/l hand
21
polarity
heroin more effective than morphine. morphine- OH which is polar. when becomes heroin, replaced by less polar, diccolves and reaches brain better in higher concentrations in the body
22
ring strain
penicillin bonds to enzyme, synthesizes to cell wall, blocks action
23
combinatorial chem and parallel synthesis
library of drugs tried, combine beads, shape to active site of enzyme quantity levels
24
modifying polarity
make less polar so will dissolve in certaini areas of body ammonia to salt oic acid to salt
25
chiral auxilliaries
synthsize desirable isomer
25
LSD
indole ring structure. dizzines, distortion
26
psilocybin
shroom. hallucination
27
marijuana
hashish. relax, confusion medicinal use dangerous
28
strong analgesics
morphine, codeine. opiates, herion. block pain from surgery