Meds

Question 1

Induction Dose of Versed

Answer 1

1-4 mg

Question 2

Induction Dose of Fentanyl:

Answer 2

1-3 mcg/kg

Question 3

Induction dose for Propofol

Answer 3

2 mg/kg

Question 4

Induction dose for Lidocaine

Answer 4

1-1.5 mg/kg

Max of 100 mg

Question 5

Induction dose for Roc:

Answer 5

0.6 mg/kg

1.2 mg/kg for RSI

Question 6

Induction dose for Sucs:

Answer 6

1 mg/kg

Question 7

Induction dose for Ketamine:

Answer 7

0.5 - 1.5 mg/kg

Question 8

Induction dose for Etomidate

Answer 8

0.3 mg/kg

Question 9

Dose for Neo:

Answer 9

100 mcg IVP
or
gtt of 40-80 mcg/min

Question 10

Dose for Ephedrine:

Answer 10

5-10 mg IVP

Question 11

IVP dose for Vaso:

Answer 11

1-2 units

Question 12

Dose for Precedex:

Answer 12

1 mcg/kg over 10 min followed by gtt @ 0.2-0.7 mcg/kg/hr

Question 13

MOA for Versed:

Answer 13

Binds to the alpha/gamma subunits on GABA receptor

Enhances receptor’s affinity for GABA

Enhanced opening of Cl- channels

Question 14

MOA for Fentanyl:

Answer 14

Mu Opioid Agonist

Increases K+ conductance, decreases Ca conductance (↓ cAMP)

Question 15

MOA for Lidocaine:

Answer 15

Blocks VG Na+ channels and prevents AP conduction

Question 16

MOA for Propofol

Answer 16

Modulates GABA through through GABA-A receptors

↑ Cl- conductance = hyperpolarization of postsynaptic membrane & neuron = sedative & hypnotic effects

Question 17

MOA for Roc:

Answer 17

Blocks Ach release from pre-junctional sites

Competes for alpha subunits on post-junctional nAch R’s

prevents conformational change - inhibition of Na+ conduction - no impulses

Question 18

MOA for Sucs:

Answer 18

Attaches to 1 or both alpha subunits on nACh Rs

Mimics Ach @ NMJ - causes depolarization of the post-junctional membrane

Post-junctional membrane cannot respond to subsequent release of Ach

Question 19

MOA for Ketamine:

Answer 19

• NMDA antagonist: blocks Ca influx - ↓ release of glutamate
• Opioid receptor antagonist

Question 20

MOA for Etomidate

Answer 20

Binds to GABA-A receptor & increases receptor’s affinity for GABA

Question 21

MOA for Neo:

Answer 21

Alpha 1 Agonist
(mimics the alpha effects of Norepi but not as potent)

Question 22

MOA for Ephedrine:

Answer 22

Non-catecholamine Sympathomimetic

Direct acting: alpha & beta agonist (non-selective)
Indirect: NE & endogenous catechol. release

Question 23

MOA for Precedex

Answer 23

Stimulates a2 receptors & causes presynaptic inhibition (turns down SNS)

a2A: sedation, hypnosis, sympatholysis

a2B: Vasoconstriction, anti-shivering, analgesia, Ca-linked

a2C: learning, startle response

Question 24

Onset, DOA of Versed:

Answer 24

Onset: <1 min
DOA: 2-6 hrs

Question 25

Onset, DOA of Fent (induction)

Answer 25

Onset: 30-60 secs DOA: 10-20 min

Question 26

Onset, DOA of Lidocaine (Induction)

Answer 26

Onset: 1 min DOA: 10-20 min

Question 27

Onset, DOA of Propofol (induction)

Answer 27

Onset: 30-60 sec DOA: 1-8 min

Question 28

Onset, DOA for ROC

Answer 28

Onset- 2-3 mins DOA: 30-40 min

Question 29

Onset, DOA for Sucs

Answer 29

Onset: 30-60 secs DOA: 3-5 mins (5-10 mins)

Question 30

Onset, DOA for Ketamine:

Answer 30

Onset: 1 min DOA: 10-20 min

Question 31

Onset, DOA for Etomidate

Answer 31

Onset: 1 min DOA: 3-10 min

Question 32

Onset, DOA for Neo:

Answer 32

Onset: 10-15 min DOA: 15 min

Question 33

Onset for Vaso:

Answer 33

10-15 mins

Question 34

Doses: Anti-Emetics Zofran Phenergan Dexamethasone Inapsine Reglan Pepcid

Answer 34

Zofran: 4-8mg Phenergan: 6.25-25 mg Dexamethasone: 4 mg Inapsine: 0.625 mg Reglan: 10-20 mg Pepcid: 20 mg

Question 35

Dose for Sugammadex:

Answer 35

2 mg/kg for moderate block (2/4 TOF twitches) 4 mg/kg for deep block (no TOF, 1-3 PTF) 8-16 mg/kg for Extreme block (no TOF or PTF)