Meds

Question 0

CCB

Answer 0

Cause peripheral edema
Constipation
Headache

Question 1

Risperidone

Answer 1

D2 antagonist - causes weight gain, hyperprolactinemia,

Question 2

Steroids

Answer 2

Cause acne that is monomorphic pink papules with no comedones

Question 3

Nitroglycerin effects

Answer 3

Dilates capacitance vessels - decreases preload

Dilates arterioles - decreases afterload –> decreases BP –> reflex tachycardia and increased contractility

Question 4

Amiodarone

Answer 4

Don’t give to patients with pre-existing lung disease!!! can cause ARDS, interstitial pneumonitis, organizing pneumonia

Question 5

Lidocaine

Answer 5

Increases the risk of asystole in patients with acute coronary syndromes

Decreases risk of V-fib

Question 6

Which drugs are CI in heart block?

Answer 6

Bb
Digoxin
CCB

Question 7

Which things increase warfarin effect?

Answer 7

Acetaminophen 
NSAIDs
Ginkgo biloba
Omeprazole
Cranberry juice
Vit E
Thyroid hormone 
SSRI

Question 8

Which things decrease warfarin effect?

Answer 8

Green veggies
Carbamazepine 
Rifampin 
OCPs
Ginseng 
St. John's wort

Question 9

Efavirenz

Answer 9

Causes vivid dreams, insomnia

Question 10

Didanosine

Answer 10

Pancreatitis

Question 11

Beta 2 agonists used for preterm labor tocolysis

Answer 11

May result in pulmonary edema due to tachy from beta 1 stimulation (decreased filling time and subsequent backup)

Question 12

Risperidone

Answer 12

Most likely atypical antipsychotic to cause extrapyramidal sx and tardive dyskinesia

Question 13

Clozapine

Answer 13

Most effective atypical antipsychotic in schizophrenia
Least likely to cause extrapyramidal sx
Causes agranulocytosis

Question 14

Which medications cause crystal induced kidney injury?

Answer 14

Acyclovir
Sulfonamides
MTX 
Ethylene glycol
Protease inhibitors (-Navir)

Question 15

What can primaquine cause?

Answer 15

Methemoglobinemia

Hemolytic anemia

Question 16

What is a side effect of norepinephrine?

Answer 16

Vasospasm leading to ischemia and necrosis of the fingers and toes in hypotensive patients

Question 17

What are the drugs that cause esophagitis?

Answer 17

Tetracyclines
NSAIDs
Bisphosphonates
KCl
Quinidine
Iron

Question 18

What side effect can be seen after levo/carbidopa?

Answer 18

Hallucinations

Question 19

What drug causes livedo reticular is and ankle edema?

Answer 19

Amantadine

Question 20

Which drugs cause hyperkalemia?

Answer 20

Trimethoprim
Nonselective Bb
ACEi
Heparin 
Cyclosporine 
NSAIDs 
Succinylcholine

Question 21

What are the main side effects of sulfonylureas?

Answer 21

Weight gain

Hypoglycemia

Question 22

What are the side effects of pioglitazones?

Answer 22

Weight gain
Edema
CHF 
Bladder cancer 
Bone fx

Question 23

What are the side effects on insulin?

Answer 23

Weight gain

Hypoglycemia

Question 24

When is insulin added to Type II regimen?

Answer 24

When A1C is greater than 8.5% and metformin failed

Question 25

What is the best diabetic medication if weight loss is desired?

Answer 25

GLP-1 agonist

Question 26

What are GLP1 agonists associated with?

Answer 26

Acute pancreatitis

Question 27

What drugs cause hypothermia?

Answer 27

Typical antipsychotics : fluphenazine, haloperidol, chlorpromazine, trifluoperazine,

Question 28

What is the side effect of methimazole?

Answer 28

Agranulocytosis Teratogen Cholestatic jaundice

Question 29

What are the side effects of PTU?

Answer 29

``` Vasculitis Rash Arthralgia Hepatotoxicity Agranulocytosis ```

Question 30

What are the side effects of radio iodine ablation?

Answer 30

Permanent hypothyroidism | Worsening of opthalmopathy

Question 31

What is the blackbox warning of PTU?

Answer 31

Severe liver injury | Acute liver failure

Question 32

Which drugs cause cholestasis?

Answer 32

Chlorpromazine Anabolic steroids Nitrofurantoin Erythromycin

Question 33

Which meds cause fatty liver?

Answer 33

Tetracyclines Valproate Antiretrovirals

Question 34

Which meds cause hepatitis?

Answer 34

Halothane Phenytoin Isoniazid Alpha-methyl dopa

Question 35

Which drugs granulomatous liver problems?

Answer 35

Allopurinol | Phenylbutazone

Question 36

What can primidone do?

Answer 36

Precipitate acute porphyria - abdominal pain, confusion, headache, hallucinations and dizziness

Question 37

Why should CCBs NOT be used in acute MI or CHF?

Answer 37

They cause reflex tachy and therefore increase demand on the heart Also, cause edema

Question 38

Why are beta blockers contraindicated in pulmonary edema and CHF?

Answer 38

Because hey decrease contractility and can lead to worsening of the fluid overload Should be started for long term management once the patient is euvolemic

Question 39

Which meds can cause NASH?

Answer 39

``` Amiodarone Steroids Diltiazem Tamoxifen HAART TPN ```

Question 40

What drugs can't be used for PE in a patient with a GFR less than 30?

Answer 40

Enoxaparin Fondaparinix Rivaroxaban Because decreased clearance increases the anti-Xa activi level and therefore the bleeding risk

Question 41

Which meds cause megaloblastic anemia due to impaired folic acid absorption?

Answer 41

Phenytoin Primidone Phenobarbital

Question 42

Erythropoietin causes what side effects?

Answer 42

HTN Flushing Headache Red cell aplasia

Question 43

What are the side effects of cyclosporine?

Answer 43

Nephrotoxicity: most common and severe --> hyperuricemia with gout, hypophosphatemia, hyperkalemia, hypomagnesemia HTN - tx with CCB Neurotoxicity: headache, visual disturbances, seizures, tremors, akinestic mutism Infection Malignancy : SCC of the skin and lymphoproliferative disorders Gingival hypertrophy and hirsutism GI

Question 44

What does verapamil do to the digoxin concentration?

Answer 44

Increases it by decreasing its renal excretion

Question 45

What does digoxin toxicity cause?

Answer 45

``` Anorexia Nausea Vomiting Visual changes Bi ventricular tachy and accelerated junctional rhythms ```