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Pharm II > Meds and classes > Flashcards

Meds and classes Flashcards

1
Q

*Quinidine (Quinora)

A

*Class IA sodium channel blocker

Cardiac arrhythmia

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2
Q

Procainamide (Pronestyl)

A

Class IA sodium channel blocker

Cardiac arrhythmia

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3
Q

*Lidocaine (xylocaine)

A

*Class IB sodium channel blocker

cardiac arrhythmia

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4
Q

*Flecainide (Tambocor)

A

*Class IC sodium channel blocker

cardiac arrhythmia

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5
Q

*Propanolol (Inderal)

A

*Class II Beta blocker (nonspecific)
(-) inotropic agent
(cardiac arrhythmia)

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6
Q

Acebutolol (Sectral)

A

Class II beta blocker (B with ISA)
(-) inotropic agent
(cardiac arrhythmia)

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7
Q

Esmolol (Brevibloc)

A

Class II Beta blocker
(-) inotropic agent
(cardiac arrhythmia)

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8
Q

Metroprolol (Lopressor)

A

Class II Beta Blocker (B1 specific)
(-) inotropic agent
Cardiac arrhythmia
also used in CHF

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9
Q

Nadolol (Corgard)

A

Class II Beta blocker (nonspecific)
(-) inotropic agent
Cardiac arrhythmia

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10
Q

Timolol (Blocadren)

A

Class II Beta Blocker (nonspecific)
(-) inotropic agent
Cardiac Arrhythmia

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11
Q

Atenolol (Tenormin)

A

Class II Beta Blocker (B1 specific)
(-) inotropic agent
Cardiac Arrhythmia

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12
Q

Amiodarone (Cordarone)

A

Class III K+ channel blocker (prolong repolarization)

Cardiac Arrhythmia

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13
Q

Sotalol (Betapace)

A

Class III K+ channel blocker (prolong repolarization)

Cardiac Arrhythmia

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14
Q

*Verapamil (Calan, Isoptin)

A

*Class IV CCB

Cardiac arrhythmia

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15
Q

Diltiazem (Cardizem)

A

Class IV CCB

Cardiac arrhythmia

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16
Q

Adenosine (adenocard)

A

Misc: natural nucleoside that enhances K+ conductance and inhibits Ca influx
Cardiac Arrhythmia

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17
Q

Digoxin (lanoxin)

A

Misc

Cardiac Arrhythmia

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18
Q

Magnesium

A

Misc. Mechanism unknown

DOC for Torasde de pointes and Digitalis induced arrhythmia

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19
Q

Potassium

A

Misc. Increases serum K+, depolarization

Cardiac Arrhythmia

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20
Q

*Acetazolamide (Diamox)

A

*Carbonic Anhydrase Inhibitor

Diuretic

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21
Q

Brinzolamide (Azopt) topical

A

Carbonic Anhydrase inhibitor

Diuretic

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22
Q

Dorzolamide (Trusopt) topical

A

Carbonic Anhydrase Inhibitor

Diuretic

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23
Q

*Furosemide (Lasix)

A

*Loop Diuretic

used in CHF, HTN

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24
Q

Bumetanide (Bumex)

A

Loop Diuretic

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25
Torsemide (Demadex)
Loop Diuretic
26
Ethacrynic Acid (Edecrin)
Loop Diuretic | used in CHF
27
*Hydrochlorothiazide (Esidrix)
*Thiazide Diuretic | used in CHF, HTN (DOC)
28
Chlorothiazide (Diuril)
Thiazide Diuretic
29
Chlorthalidone (Hygroton)
Thiazide Diuretic | - cmpd related to thiazides
30
Metolazone (Mykrox)
Thiazide Diuretic - compound related to thiazides Used in CHF, HTN
31
Quinethazone (Hydromox)
Thiazide Diuretic | - compound related to thiazides
32
Indapamide (Lozol)
Thiazide Diuretic -compound related to thiazides *direct vasodilator, hepatic metabolism Used in CHF, HTN
33
*Amiloride (Midamor)
*K+ sparing Diuretic (Direct inhibitor of Na flux) | Used in CHF, HTN
34
Triamterene (Dyrenium)
K+ sparing Diuretic (direct inhibitor of Na flux) | Used in CHF
35
Spironolactone (Aldactone)
K+ sparing diuretic (Aldosterone antagonist) | Used in CHF
36
Eplerenone (Inspra)
K+ sparing diuretic (Aldosterone Antagonist) | Used in CHF, HTN
37
*Mannitol (Osmitrol)
*Osmotic Diuretics
38
Isosorbide (Ismotic)
Osmotic Diuretic
39
Glycerin (Osmoglyn)
Osmotic Diuretic
40
Urea (Ureaphil)
Osmotic Diuretics
41
Desmopressin
ADH agonist, synthetic ADH
42
Conivaptan (Vaprisol)
ADH antagonist; non peptide V1 and V2 receptor antagonist
43
Tolvaptan (Samsca)
ADH antagonist | non peptide V2 vasopressin receptor antagonist
44
Demeclocycline (Declomycin)
ADH antagonist blocks V2 receptor 2nd messenger system (use dc bc of vaptans)
45
Lithium
ADH antagonist | competes for Na excretion in renal tubules
46
Digoxin (Lanoxin)
Digitalis +Inotropic/contractile agent for CHF inhibits Na/KATPase pump
47
Inamrinone (Inocor, Amrinone)
PDE inhibitor (bipyridines) +Inotropic/contractile agent for CHF inhibit cAMP PDE, increase Ca influx, vasodilation
48
Milrinone (primacor)
PDE inhibitor (bipyridines) +Inotropic/contractile agent for CHF inhibit cAMP PDE, increase Ca influx, vasodilation
49
*Dobutamine (Dobutrex)
*Sympathomimetics +inotropic/contractile agent for CHF selective B1 agonist (less tachycardia)
50
Dopamine (Intropin)
Sympathomimetics +ionotropic/contractile agent for CHF acts on D1 (renal vasodilation), B1 (+inotropic) and alph (vasoconstriction)
51
What four drugs reduce CHF mortality
1) Aldosterone antagonists (Spironolactone, Eplerenone) 2) Beta blockers (olol) 3) ARBs (artan) 4) ACE inhibitors (pril)
52
*Captopril (Capoten) | ~all "pril"
*ACE inhibitors Diminish cardiac workload in CHF pt (backbone tx) block angiotensin I to II conversion
53
*Losartan (Cozaar) | ~all "artan"
*ARB diminish cardiac workload in CHF pts block ang II from bindign to ATI receptor
54
* Carvedilol (Coreg) | * Metroprolol (Lopressor)
*B Blocker | (-) inotropic/contractile agent, decreases cardiac workload (HR, remodeling) in early stage CHF
55
*Sodium Nitroprusside (Nitropress)
Vasodilator ~reduce preload and/or afterload and reduce remodeling of heart for CHF pt ~also used in acute angina
56
*Hydralazine (Apresoline)
Vasodilator | ~Reduce preload and/or afterload and reduce remodeling of heart for CHF pt
57
*Isosorbide dinitrate (Isordil)
Vasodilator | ~Reduce preload and/or afterload and reduce remodeling of heart for CHF pt
58
What general types of meds treat HTN | *note: combos from different groups increase efficacy and may decrease toxicity
Diuretics, Sympathoplegic agents (a2 agonists, a1 blockers, B blockers (all forms)) --> decrese SNS tone Vasodilators (NO, CCB, K channel openers, D1 receptor stimulant) ACE inhibitors ARBS
59
What general types of meds treat Cardiac Arrhythmias
``` Class I Na channel blockers Class II B blockers Class II K channel blockers (prolong repolarization) Class IV CCB others (Mg, K, Digoxin, Adenosine) ```
60
What general types of Diuretics are there
``` CA inhibitors Loop Diuretics Thiazide Diuretics K+ sparing diuretics (aldo antagonists and direct inhibitors of Na flux) Osmotic Diuretics ADH agonists and antagonists ```
61
*Clonidine (Catapres)
alpha 2 agonist *Centrally acting Sympatholytic for HTN pt decrease peripheral SNS activity on heart and BV = vasodilation
62
*Methyldopa (Aldomet)
alpha 2 agonist Centrally acting sympatholytic for HTN pt Decreases peripheral SNS activity on heart and BV = vasodilation
63
*Prazosin (minipress)
alpha 1 blocker vasodilation --> decrease BP for HTN
64
Doxazosin (Cardura)
alpha 1 blocker Vasodilation --> decrease BP for HTN
65
ACE suffix
Pril
66
B blocker suffix
olol
67
a1 blocker suffix
zosin
68
ARB suffix
artan
69
CCB suffix (generally)
dipine | *but have verapamil and diltiazem
70
Non selective B blockers
*Propranolol (Inderal) Nadolol (Corgard) Timolol (Blocadren) *NAh TIM's a non selective PRO
71
Selective B1 blockers
*Metroprolol (Lopressor) Atenolol (Tenormin) Nebivolol (Bystolic) Acebutolol (Sectral) ~for HTN *beta 1 met athena's new ace"
72
B blockers with ISA
*Acebutolol (Sectral) Pindolol (Visken) ~for HTN *Pin Isa {an} ace!
73
Combined Alpha and B blockers
Carvedilol (Coreg) Labetalol (Normodyne) ~for HTN *combine lab carvings

Pharm II (12 decks)

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