meiosis Flashcards
(22 cards)
what does meiosis produce?
gametes- produces 4 genetically different daughter cells
what happens during prophase I?
chromosomes condense and become visible
nuclear envelope begins to break down
what happens in metaphase I?
pairs of homologous chromosomes pair up along the equator (independent assortment)
crossing over occurs- bivalents- cross over at chiasmata
spindle fibres form and attach to centromeres
what happens in anaphase I?
spindle fibres contract
chromosomes are pulled to opposite poles of cell- some of the chromatids are now recombinant
what happens during telophase 1?
chromosomes decondense
nuclear envelope reforms
what is formed at the end of the first division of meiosis?
two haploid cells formed each with 1 copy of each chromosome (maternal and paternal) but different combination of alleles
what happens during prophase II?
chromosomes condense and become visible
nuclear membrane begins to break down
what happens during metaphase II?
individual chromosomes line up along equator
spindle fibres form and attach to centromeres
what happens during anaphase II?
spindle fibres contract
sister chromatids are pulled to opposite poles of the cell
what happens during telophase II?
chromosomes decondense
nuclear envelope reforms
what is formed after the second division of meiosis?
4 genetically different haploid cells
each gamete has unique combination of alleles and only single chromosome of maternal/paternal
what is a bivalent?
chromosomes that are attached together in a homologous pair
what is the chiasmata?
the point where chromatids from different chromosomes cross over
why is the second division needed in meiosis?
to split the chromatids of each chromosome that were produced when the DNA was replicated
what are the causes of genetic variation?
MEIOSIS- crossing over and independent assortment
random fertilisation
mutation
environmental factors
describe how crossing over leads to genetic variation?
during metaphase I, homologous chromosomes pair up to form bivalents
the chromatids from different chromosomes in a pair cross over, the cross over point is called the chiasmata
genetic material is exchanged between the chromosomes
the chromatids from the different chromosomes in the pair carry the same genes but have different alleles
this means crossing over leads to new combinations of alleles
describe how independent assortment leads to genetic variation?
the homologous pairs line up at the equator during metaphase I
the maternal and paternal chromosomes can line up on either side (it is random), the arrangement of one pair doesn’t influence arrangement of other pairs, they all line up independently of each other
at anaphase I, the chromosomes of homologous pairs are separated, each chromosome moves to opposite pole
this leads to new combination of alleles
how do mutations cause genetic variation?
mutations are changes in base sequence of a gene
this created new alleles
how does random fertilisation cause genetic variation?
any egg can be fertilised by any sperm
different combinations of alleles are brought together
how do environmental factors lead to genetic variation?
affect expression of a gene in the phenotype
where can mutations in number of chromosomes arise from?
spontaneously by chromosome non-disjunction during meiosis
what is the mathematical formula for determining the number of possible combinations of chromosomes for each daughter cell of meiosis?
2^n where n is number of pairs of homologous chromosomes