Melanoma Flashcards
1
Q
What is a measure of prognosis in melanoma?
A
Thickness
2
Q
What criteria can be used to predict likelihood of melanoma?
A
ABCDE criteria
Glasgow 7-point checklist
3
Q
What mutation is associated with melanoma?
A
BRAF mutation - V600 is the most common location of mutation
4
Q
What is the investigation of choice for suspected melanoma?
A
Excisional biopsy
5
Q
What are the different subtypes of melanoma?
A
Superficial spreading (most common) Lentigo melanoma Nodular melanoma (most aggressive) Acral (can be subungal melnoma) Desmoplastic melanoma (rare, and hard to diagnose)
6
Q
What does the ABCDE criteria stand for?
A
Asymmetry of lesion Border (irregular) Colour irregularity Diameter > 6mm/Different from other lesions Evolving over time
7
Q
What is the treatment for melanoma?
A
Wide-local excision (definitive Tx)
8
Q
Where can melanoma metastasise to?
A
Lung
Liver
Brain
Bone
8
Q
Where can melanoma metastasise to?
A
Lung
Liver
Brain
Bone
9
Q
Name 2 immunotherapy drugs for melanoma
A
Ipilimumab
Vemurafenib
