MELAS Flashcards
1
Q
What is the inheritance pattern for MELAS?
A
Mitchondrial
2
Q
What are the clinical manifestations of MELAS?
A
- Stroke-liked episodes
- Basal ganglia infarction
- Calcifications
- Diabetes mellitus
- Thyroid dysfunction
- Other endocrinologic abnormalities
- Hearing loss
- Elevated pyruvate and lactate with increase with exercise
