Membrane Proteins Flashcards

(4 cards)

1
Q

Membrane Proteins

A

Responsible for membrane functions

Proteins associate with membrane in various ways:
Transmembrane
Integral
Peripheral

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2
Q

Membrane proteins cross the lipid bilayer

A

SINGLE-PASS PROTEINS: cross once as a single alpha helix

MULTI-PASS PROTEINS: cross multiple times as series of a-helix or as beta helix (closed barrel)

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3
Q

Majority of membrane proteins are glycosylated in eukaryotes

A

Sugars are added in lumen of ER & Golgi

Oligosaccharide chains are always present on noncytosolic side

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4
Q

Some membrane proteins are ASSOCIATED (verbunden)

A

Attached to either side of the membrane

  • bound by noncovalent interactions with TM proteins
  • bound via covalently attached lipid groups
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