Membrane Proteins Glycosylated Flashcards
(6 cards)
0
Q
N linked oligosaccharide
A
Attachment of that by the enzyme oligosaccharyl transferase
1
Q
N-acetyl glucosamine
A
Linked to nh2 group of asparagine
2
Q
Precursor oligosaccharide
A
Held by dolichol
3
Q
Why we glucosylate 1
A
Help proteins fold, er chaperones calnexin and carlreticulin binds oligosaccharides of particulate folded protein to stop aggregation
4
Q
Why we glucosylate 2
A
Helps direct proteins to their final destination, carbohydrate proteins called lectins help guide er to Golgi transport and protein sorting on the trans-Golgi network
5
Q
Why we glucosylate 3
A
Help proteins function, oligosaccharides on cell surface proteins interact with lectins and function in cell to cell adhesion roles in signalling
