Memory Flashcards

1
Q

What is memory?

A

The ability to store and retrieve information over time

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2
Q

auditory memory

A

Echoic- hold info 3 sec

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3
Q

visual memory

A

iconic- holds info 250 ms

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4
Q

About neuronal architecture and memory…

A
  • By learning something new your brain structure is being changed as new information is given and you form new axonal and neuronal connections which store the information.
  • Neurones die over the course of life time, die all the time, memories not stored in one neurone for this reason otherwise they would be lost. Memory is instead stored in multiple neurones in a distributed process - neuronal network.
  • You cant eradicate a memory by attacking a memory as you don’t know which ones its distributed within. Lose memories in illnesses such as dementia because so many have been lost, can lose up to 80% before you even notice the change. Whole sections can die and you would only notice that you’re slowing down. When someone presents with dementia they will have already lost over 50%, often whole sections.
  • Neural architecture acts the same as the internet, there’s always multiple routes to the same neurone, so if one is blocked then it’ll take another one to get the information.
  • Brain stores information at different levels of readiness. In Alzheimer’s and dementia lose the useless information first, and last the things you need all the time such as how to go to the toilet and the name of your partner. Your brain prioritises information based on utility and relevance to you.
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5
Q

What are the types of memory?

A
Iconic memory
short term memory
working memory
immediate term memory
long term memory
episodic memory (autobiographical)
semantic memory
declarative memory
procedural memory
prospective memory
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6
Q

What is iconic memory?

A

this is the after image on retina if visual, tactile feeling on skin if you have been touched by something for long enough, echoic if you still hear a sound after it has stopped. These stores are very momentary, 250ms.

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7
Q

What is short term memory?

A

online storage for things that are happening now. Phone numbers originally 7 digits as can only remember 7-8 things for about 30 seconds (unless constantly sub-vocally rehearsed). 7 pieces of information +/- 2 (standard deviation) is the average limits of human memory. Short term memory is the old fashioned way of saying working memory

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8
Q

What is working memory?

A

three components: phonological loop (auditory info), visuo-spatial sketchpad (visual), and something resembling consciousness and attention. As there is a consciousness part this means conscious awareness is very limited, but unconscious awareness is vast (eg hearing name across the room even though working memory is full

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9
Q

What is immediate term memory?

A

a new form. This is the bit between working and long term. Stored for up to 2 days. Eg location of car in carpark

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10
Q

What is long term memory?

A

potentially forever eg Paris is the capital of France. Divided into separate sorts of stores (episodic/autobiographical which is events which have happened to you, totally separate to semantic memory which is factual memory eg paris - these two are functionally separate, can lose one and not the other

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11
Q

What is episodic (autobiographical) memory?

A

events which have happened to you

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12
Q

What is semantic memory?

A

factual memory

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13
Q

What is declarative memory?

A

things you know you know, when something is on the tip of your tongue

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14
Q

What is procedural memory?

A

memory for doing things such as riding a bike, driving, swimming

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15
Q

What is prospective memory?

A

ability to remember to do things in the future, e.g. important tasks you need to do late in the day/week

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16
Q

What is expectation in relation to memory?

A

Expectation is a memory phenomenon when you’re doing something and your brain fills in the information its expecting, eg hearing mum shout you or jumping when you see something outside at night. Also means that if you see someone out of context when you’re not expecting it you struggle to remember who they are or where you know them from.

There is evidence that human memory is rapidly declining due to technology, in particular google.

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17
Q

What are the critical concepts in neuropsychology in relation to memory?

A
  • Dissociation and double dissociation
  • Help to identify neural substrates of various brain functions
  • Dissociation = when you know localisation of brain damage or lesion and find that one function is knocked out by other related functions are preserved eg individual loses ability to name category of animals but can name all other objects
  • Double dissociation = lesion in specific brain area impairs function x but not y then demonstrate that lesion of separate brain area impairs y but not x
  • Patternson and Plaut “the gold standard was always a double dissociation” 2009
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18
Q

What are the three key processes in memory?

A
  • Encoding - processes occurring during initial encounter with to be remembered stimulus = stage 1
    • Storage - storage in the memory system = stage 2
    • Retrieval - recovering stored information form the memory system = stage 3

Forgetting can result from failure of any of these stages, rather than a process in itself.

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19
Q

About encoding and storing memories…

A

Encounter with initial stimulus you’re trying to remember eg a lecture, you’re trying to record it by paying attention in order to hopefully remember it.

The deeper the level you encode something to the level you remember it the better you remember it. To deepen the level of encoding you pay more attention, write notes, etc. asking questions makes you encode to a deeper level because you think about it I a deeper way as you have to search your memory for answers which activates similar structures which mean when you are told the answer you can hook it onto something. Making things personally relevant also means that you can encode things deeper.

Storage is transferred between types of memory. One of the best ways to store memory is by asking questions, doing practice questions, making it relevant to you and making notes (rehearsal not shown to have much effect). Consolidation is the transfer from short term to long term.

In retrieval the memory is reconstructed more than recollected, you are not accessing the exact same thing but just the jist of it. We reconstruct things, which we know by telling stories about things that happened - they change slightly. This tells us that human memory is not very reliable - scientific evidence from eye witness testimonies which are very inaccurate in at least 50% of cases.

What we think of as forgetting can result from failure at any of these stages.

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20
Q

About memory structure

A

A basic model is the multi-store model of memory (Atkinson and Shriffin, 1974)

sensory inputs > sensory store >(encoding)> short term memory (retrieval) long term memory

When gets to long term memory, long term memory has capacity which is almost infinite if you can always lay down memories.

Have done studies to try and test the capacity of this, by showing around 10,000 faces you’ve never seen before, and then the next week they show you them and ask if you’ve seen them before, and they keep increasing the number over months and they haven’t found the capacity of limitation.

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21
Q

What is sensory memory?

A
  • Auditory [echoic] memory - holds information for approximately 3 seconds
  • Visual [iconic] memory - holds information for approximately 250ms

Have all the other modalities too, but there is very little research on them because it is very rare. 50% of brain is vision so 90% research on vision, 10% on auditory, very little on olfaction. Smells are weirdly one of the most infallible sources of memory however.

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22
Q

About short term memory

A

• STM - now termed Working Memory (Baddeley and Hitch, 1974)
• This consists of three components:
- Central executive: this resembles what we would call ‘attention’
- Phonological loop: holding information in a speech-based form
- Visuo-spatial sketchpad: specialised for holding cisual and spatial information

Older form, more historical but still know it.

Central executive - this is almost a representation of consciousness/attention. Attention is a way of deepening the level of encoding. The brain pays most attention to information that is relevant to you. This biases us in terms of attention, means that what we see in the world is not what’s there but is what is interesting to us. If you change who you are as a person, you have trouble remembering things you learnt as your old self - this is called state dependent memory. Best example is locational memory - what you learn in this class, if you took the exam in the same room as the lesson then you would get about 5% more on the paper.

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23
Q

About working memory…

A

• WM is a much more dynamic store than a unitary STM
• Working memory has a limited capacity (LTM is theoretically without limit, in both capacity and duration of storage)
- It is usually found that we can only store around 7 ± 2 pieces of information in memory (Miller, 1956)
- Be beware of chunking - grouping bits of information to make remembering easier

Chunking is how you group bits of information, for example not remembering each number in a phone number, but putting parts of the number together.

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24
Q

Inference in memory recall

A

Inference in WM

- Traces only remain in WM with repeated rehearsal (ie attending to the information)
- They are therefore prone to interference
- Retroactive interference: new information interferes with the retention of old information in WM (trying to remember your old phone number, having used your new number for a few months; finding it difficult to revert back to manual gear changes having recently been shown how to use an automatic)
- Proactive interference: old information interferes with the recall of new information (mistakenly giving your old phone number instead of your new one; attempting to change gears manually in a newly bought automatic)

An example of interference is making the person think about something completely different when trying to remember something else - when new information interferes with old (retroactive) and when old information interferes with new information (proactive)

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25
Q

What is the primary-recency effect?

A

Primacy-Recency or the Serial Position Effect
When presented information in serial order, we remember more form the beginning and end of the list, at the expense of intermediate items.

26
Q

What are the levels of processing (Craik and Lockhart 1972)?

A

Craik and Lockhart - 1972

- Depth of encoding determines later memory for information
- Processing at encoding can be shallow or deep. The greater the processing the meaning of stimuli at encoding the deeper the level of processing and greater likelihood of later storage and retrieval
- Importantly Craik and Lockhart disagree that rehearsal will improve LTM as it just repeats previous operation. BUT rehearsal has beneficial effects but they are small and nor for every type of memory eg prospective memory may not benefit
27
Q

About long-term memory

A

Craik and Lockhart - 1972

- Depth o encoding determines later memory for information
- Processing at encoding can be shallow or deep. The greater the processing the meaning of stimuli at encoding the deeper the level of processing and greater likelihood of later storage and retrieval
- Importantly Craik and Lockhart disagree that rehearsal will improve LTM as it just repeats previous operation. BUT rehearsal has beneficial effects but they are small and nor for every type of memory eg prospective memory may not benefit
28
Q

What is consolidation?

A

STORAGE INTO ltm

Involves structural change: the pattern of neural pathways are changed

- Long term potentiation: strengthening of synapses, believed to be the cellular foundation for memory
- Research into how to induce LTP useful for dementia treatment - rats given NMDA receptor antagonists display memory deficits. Mice bred with enhanced NMDA function show greater LTP and better memory

Requires metabolic activity for minutes/hours after the stimulus has been presented.

Believed that the hippocampus plays a vital role in consolidation.

Human memory has got significantly worse over the last 20 years due to this process being weakened by the advent of google. Hippocampi are getting smaller as we are externalising memory to smart phones etc.

29
Q

What is retrieval (memory)?

A
  • Cue required (eg prompt, reminder, question)
  • Original stimulus reconstructed using information from cue
  • The more information available, the easier the retrieval
  • A good ‘filing system’ also aids retrieval - eg mnemonics (memory aids, Method of Loci), make something personally relevant to you and you’re more likely to remember it
  • Retrieval can be affected by interference - proactive (new phone number replaces old number), retroactive (old routine home blocks new route home)
  • Tip of the tongue phenomenon

We know that memory isn’t just recalling what you laid down - it is reconstructive.

Retrieval even from long term memory can be interfered with by the same processes as in short term memory.

30
Q

What are factors affecting retrieval?

A

Levels of processing
- The more something is elaborated at the time of encoding, the easier it will be to retrieve

Organisation
- Of concepts in memory (also, associations between concepts stored in LTM may facilitate recall)

Context
- Being in the same place/emotional state as the time of encoding facilitates recall - State Dependent Memory

Organisation of concepts in memory affects how you retrieve them. The hardest thing you could be asked to remember is information that you have nothing similar to in the past (similar to if you don’t have visual stimuli from birth you cant see even when given sight back later in life). This is why there is some evidence that if your critical period during childhood is more varied and exciting you will do better in life as - has been seen in rat studies where brains bigger, denser, more neuronal connectivity. This tells us that you can make your brain better than biology gave you through environmental use.

State dependent information also important for mood - if taught something drunk you wont remember it sober, but drunk you will - also works with drugs.

31
Q

What is declarative knowledge?

A

Declarative knowledge (sometimes known as explicit memory):

- Memory for facts, for information that can be conveyed by statements
- Involved conscious recollection of events/facts
- Encompasses semantic and episodic memories
- Eg your birthday
32
Q

What is non-declarative knowledge?

A

Non-declarative:

- Generally doesn’t involve conscious recollection eg procedural memory
- Implicit memory
- Priming
33
Q

WHAT is implicit memory

A

Implicit memory: one of the two main types oflong-term human memory. It is acquired and used unconsciously, and can affect thoughts and behaviours. One of its most common forms isprocedural memory, which helps people performing certain tasks without conscious awareness of these previous experiences. Can work out if implicitly racist using this by looking at speed of processing these things,

34
Q

what is priming

A

Priming: where one concept being active in your mind leads to another concept being active eg bread = butter, doctor = nurse. One concept primes another. You self-prime yourself by your interests, if your really love football you will prime yourself to notice all things football in the environment.

35
Q

About procedural memory

A

Procedural knowledge
- Memory for how to do things/skills
- Often in the absence of conscious recollection
Eg how do you tie your shoelaces, driving, riding a bike, playing chess

This form of memory is also dissociated from the others. Can lose all other forms of memory but still be able to do things using this form of memory.

Chess is interesting because they can see it and don’t think they know how to play as don’t think they ever have before, but if you tell them to guess then they can do it perfectly.

This is an unconscious form of memory and it can’t access conscious.

36
Q

About semantic and episodic memory

A

This form of memory is also dissociated from the others. Can lose all other forms of memory but still be able to do things using this form of memory.

Chess is interesting because they can see it and don’t think they know how to play as don’t think they ever have before, but if you tell them to guess then they can do it perfectly.

This is an unconscious form of memory and it can’t access conscious.

37
Q

About episodic/autobiographical memory

A
  • Most episodic memory decline over time however decline is not uniform over all memories eg
  • Behrick et al 1975 - memories of student days showed remarkable preservation - reminiscence bump = surprising perseverance of memories occurring between ages of 10 and 30. why?

Most episodic memories decline over time but not uniform over all memories.

Memory across human lifespan interesting as if get someone at 80 to recount the whole life they get reminiscence bump and get a lot of information between the age of 10 and 30. partly primacy effect as before 10 structures for laying down memories aren’t properly developed, and because the time in this period is an important transitional time, and should make this time a good part of your life as will remember it forever, this is also because during this time you’re exposed to a lot of new experiences. These are emotionally significant events. If they are new experiences then there cant be proactive interference as you have never done it before. Also have a bias towards positive rather than negative memories. Brain has some process where it rewrites your own history as you age - selectively forgets negative things and then you remember your past better than it actually was.

38
Q

What is the reminiscence bump?

A
  • Stability of early adulthood memories is remarkable
  • Why
  • Majority of first time experiences. Novelty is memorable because of the lack of proactive interference from previous learnings
  • More evidence for reminiscence bump for positive than negative memories (Bertsen and Ruben, 2002)

Facebook and social media exacerbates this as we mostly tend to post positive things, biasing ourselves. Facebook is like a selectively positive diary, if compared with actual diaries we see that this fully positive life is fake.

39
Q

What are flashbulb memories?

A
  • Flashbulb memory = detailed and extremely vivid memories regarding circumstances surrounding very shocking event eg September 11th
  • Only occur with shocking and emotionally significant events. Evolutionarily adaptive?
  • Emotional arousal during encoding enhances retention
  • Also frequently rehearsed and talked about

Memories where something happens with such great significance that you can’t ever forget it - eg 9/11

Happens with things that are usually negative and very different and are encoded very rapidly because there is emotion associated with (amygdala, limbic system) and this encodes it in a different way with memory and emotion. This is evolutionary for survival, useful to remember this information so as to avoid it as well. Can have personal versions of this as well not just famous things for all people, eg first real breakup. This is also partly how trauma memory works.

You never forget flashbulb memories, and it is one instance memories.

40
Q

What is recognition?

A
  • Sensing that a stimulus has been previously encountered, sense of familiarity
    • Generally easier than recall, as information is contained in the cue
      Recognition can be direct from a set stimuli or from a mental search of LTM store
41
Q

What is recall?

A
  • Reconstruction of a stimulus using the information available from the cue and information from LTM
    • Checked by the process of recognition
    • Greater ‘cognitive demand’ than recognition
      Recall can be direct from the cue or arise after problem-solving strategies have been employed
42
Q

About forgetting…

A

The main causes of forgetting from either working memory or long-term memory:

Passage of time:

- Rapid decay of information from WM
- Cell death leads to loss of LTM (can be accelerated eg dementia)

Interference:

- Interference to storage in WM eg pro/retroactive
- Connections are remolded over time in LTM, influenced by pro- and retroactive interference of information
43
Q

What is the relationship between age and memory?

A

Phenomena

- Infantile amnesia = inability to remember events from early childhood
- Generally people can not remember anything before 2 years. First memories usually occur between 2 and 5 years. Probably because brain regions responsible for episodic memory are nor sufficiently developed
- Reminiscence bump = preserved memories for 10 to 30 years (many first time occurrences)

Normative aging:

- Speed of processing declines (perfect 1994)
- Memory declines and forgetfulness increases but shouldn't interfere with ongoing functioning

Everyone has infantile amnesia
30-60 age period kind of gets lost, as opposed to the 10-30 gap

44
Q

What did Freud suggest in 1915 (to do with memory repression

A

suggested threatening information is often blocked from conscious awareness

most of this evidence was based on adult patients that often spontaneously retrieve memories of being abused as children that they report no previous memory of.

45
Q

experiment conducted by Clancy et al 2000 on repression

A
  • Butter, food, eat, sandwich, rye, jam, milk, flour, jelly, dough, crust, slice, wine, loaf, toast
  • Nurse, sick, lawyer, medicine, health, hospital, dentist, physician, ill, patient, office, stethoscope, surgeon, clinic, cure
  • Bread? Doctor?
  • Clancy et al 2000 compared women with recovered memories of childhood sexual abuse, with women who believed they were abused but could not recall it and women who had always remembered abuse and controls.
46
Q

issues on the researches of memory repression

A
  • Also issue of prompting – subsequent studies have shown that adult patients that admit to reporting false recovered memories had clinicians that categorically suggested they had been abused as children
  • This finding relates to the literature of eyewitness testimony and its unreliability.

Block things out so that we don’t have to keep reliving it. The evidence is very mixed on whether this exists at all.

Confabulation is when you remember things in a different way but that is plausible. Remember things that weren’t there for example.

Something worse about the peoples memories in the results to make them unsure if something happened or not.

Suggestibility factor - eg from therapists etc suggestion of abuse

47
Q

About dissociating function in WM and LTM (MILNER, 1978)

A
  • The case of HM (Milner, 1978)
    • Had surgery to cure severe epilepsy
    • After operation had near normal memory for events prior to surgery, and STM normal (approx 15 s)
    • But severe deficit for new memory of facts or of events occurring after surgery (encoding from STM to LTM).
    • Since operation he forgets the events of his life as they occur
    • Able to learn motor skills but could not remember which skills he had learned (Short term declarative)
    • Hand buzzer example

Can remember anything that happened from then on - semantic and episodic. However could learn chess which is procedural but has to guess the moves having been taught after the accident.

Every time the doctor would go in he would say hello doctor who are you and he would say I’ve never seen you before in my life and come back in 30 seconds later would say the same thing again. Doctor then used electric shock hand shake thingy after meeting about 100 times and then went out and came back and then he still says he’s never seen him before and doesn’t recognise him BUT refuses to shake hands, and said he just didn’t feel like it so he had partial awareness.

48
Q

About dissociating function in procedural and declarative memory

A
  • Temporal Lobe Amnesia (e.g. Korsakoffs)
    • Patients are able to learn skills
      ○ Procedural
    • Patients are unable to learn new facts
      ○ Declarative
    • E.g. a patient may show improved performance on a simple task over time, but each time they will show no recognition or memory of ever having performed the task before (despite obvious improvements)

Irreversible when gets to Korsakoffs
Able to learn new skills but not new facts - so declarative and semantic mainly damaged. Can have functioning episodic memory though

49
Q

About dissociating function in semantic and episodic memory (Tulving, 1989)

A
  • The case of KC (Tulving, 1989)
    • Damage to specific brain regions, (left frontal-parietal and right parieto-occipital lobes) following a traffic accident
    • Can no longer retrieve any personal memory of his past (autobiographical memory) but general knowledge remains good
    • Plays chess well but does not remember where he learned to play
    • Can learn semantic knowledge when care is taken but cannot acquire episodic knowledge
      ○ E.g. will claim never to have met people met recently, but will be more friendly towards them than people he really hasn’t met
50
Q

causes of amnesia

A
  • Amnesia can be brought about by:
    • Damage
      ○ Head injury, stroke
    • Chronic alcohol abuse
      ○ e.g. Korsakoff’s syndrome, affecting storage and retrieval processes
    • Disease
      ○ e.g. Alzheimer’s: extensive damage to cortex, progressive deterioration from some impaired memory skills (esp. episodic memory) à more general cognitive impairment
    • Reversible brain disease
      ○ Tumours, hydrocephalus, subdural haematoma, deficiencies in B1, B6, B12, endocrine disease, syphilis
    • Psychogenic Memory Loss
      ○ Abuse, war
51
Q

Amnesia

A

Most depictions of amnesia in films is someone hits their head and they lose the ability to remember who they are from the past - this is very rare and is called retrograde amnesia. The much more common form is anterograde amnesia which is where you can’t make new memories.

Also need to clinically separate into semantic and episodic to see which system is damaged.

Semantic is rarer.

Trauma could be so great that some kind of regressive mechanism is acting - people forget things because it is too traumatic.
Could also just be lying.

Common denominator of PML is that you never lose a nice memory, always traumatic things.

Following a stroke you gradually get function back, get memories back, but if a whole brain region is killed that wont recover. However we know that another area can learn and adapt to what you’ve lost, so areas around the dead area can take on some of the function. Get a slow, gradual recovery.

52
Q

anterograde amnesia

A
  • Anterograde amnesia (as in patient HM)
    • Inability to store new information
    • Inability to transfer information from STM to LTM
53
Q

retrograde amnesia

A
  • Retrograde amnesia (rarer)
    • Inability to recall information prior to trauma
    • Often following closed head injury, can be relatively short duration
54
Q

About HM and the hippocampal region

A
  • HM had both hoppocampi surgically removed yet retained information from the past.
  • Therefore suggests this is not the actual repository
  • Memories are stored in various regions of the cortex
55
Q

Biology of memory storage

A

Frontal lobe - stores certain semantic and episodic memories
Prefrontal cortex - involved in storage of STM
Motor cortex - procedural memory
Temporal lobe - formation and storage of LT semantic and episodic and also new STM
Amygdala - emotions, emotional response, emotional memories
Hippocampus - new LT semantic and episodic memories, not the repository but where theyre formed - amygdala on the end of it, close biologically as get bang for buck as it stores the memories, both lighting up saying to store quickly, perhaps one time learning
Cerebellum - storage of procedural memories and also for balance. If drink enough for long enough you permanently damage it and you get a permanent alcoholic gate

56
Q

What is hippocampal function

A
  • Memories are stored in a distributed fashion throughout the cortex
  • Therefore something has to integrate these into coherent memories
  • That something is probably the hippocampal region (Schacter, 1996)

Not only the hippocampus because can remove it and there’s still function - likely to be the regions around the hippocampus more than others.

57
Q

About temporary amnesia

A

• Can result from head injuries, psychological states or drugs
• Concussion often associated with memory loss
• Cinema experience
• Usually retrograde amnesia for events immediately preceding the cause
• Fugue states (Schacter et al. 1982)
• Occur with extreme psychological trauma often loss of previous experience and identity
• Drugs
Date rape drugs such as rohypnol can cause amnesic effects for events occurring while under the influence

Rohypnol, alcohol

Fugue states - when you have a big psychological trauma, do something horrific (eg kill someone) and then forget what you’ve done and are found wandering. Unaware of what you’re doing.

58
Q

About ageing and memory

A

• Memory across the lifespan is unequally distributed as we have seen (Rubin, Wetzler & Nebes, 1986).
• If we ask an older adult to recall their lives the following general pattern would emerge
• Infantile amnesia – failure to recall anything from first 3 years often first 5 years
• Reminiscence Bump – better memory for period 10 to 30 but strongest for positive information
• Alternative theory
• Conway & Pleydell Pearce (2000)
• Knowledge base
○ Lifetime periods – vast swathes of time defined in terms of ongoing situations
○ General Events – often repeated but related to each other
○ Specific knowledge of events
• Working self
○ Concerned with goal attainment frames knowledge in terms of progress or lack of progress towards important goals

As opposed to being because of new experiences, might be because of the Conway and Pleydell Pearce theory - the things you remember are discrete normative events, so average life would look like birth, school, university, work, tv, marriage, children, divorce??, death. This theory argues that these are the structures that we hang memories on.

Working self - anything related to you is better remembered, cognitive bias to things you’re interested in, also cognitive bias if set a goal for your life then you have a cognitive bias to anything related to that goal. This means that you notice some things more that you didn’t notice before or wouldn’t usually.

  • At advanced age memory starts to decline
  • Speed of processing slows with age (Perfect, 1994)
  • Generally normative age related decline should not interfere with daily functioning
  • Where it does its more likely to indicate a pathological process
  • Working memory declines more

Average life expectancy is 80 (M) and 81 (F), and 80 is where we class as starting to see advanced old age.

Older adults used to refer to 60-80 and after 80 were referred to as either advanced old or old-old, but have now had to create new terminology as people are living longer now.

59
Q

About amnesia research

A

• Brain damage studies are broadly supportive of the 3 types of autobiographical knowledge
○ Generally event specific knowledge is more compromised than general events or lifetime periods
○ Confabulation on basis of plausibility is common

General event autobiographical knowledge is every time you’ve been to uni - repeatedly go, similar to dating etc

60
Q

About dementia

A
  • Affects roughly 800,000 people in the UK
  • Increases with age
  • Is a syndrome associated with multiple losses
    • Memory loss
    • Speed of processing
    • Language ability
    • Understanding
    • Emotional ability
  • Alzheimers is most common form representing the majority of cases
  • 10% of individuals develop dementia at some point
  • Cure is impossible because of neurodegeneration but slowing is possible

Massive cause of memory loss.
800,000 is going up, significantly higher than schizophrenia rates, going up because living longer and lifestyle factors such as alcohol use, using your brain/lack of use.

Not just memory loss - also speed of processing, language, comprehending, emotional, personality change.

An almost certainty if live long enough is the lens of the eye wears out and get cataracts, prostate cancer, also memory loss is another certainty.

Rest of us (90% not with dementia) wont escape memory loss.

Memory loss with dementia is problematic because cure is impossible because it is caused by neuronal death. Drugs can slow it but not stop it. Slowing it is a problem though because by the time someone presents with dementia they can have lost 50% of the neurones already.

Looking currently at transplanting parts of brains, just the regions which are damaged not the whole brain. Could be taken from elsewhere or grown.

Other treatment possibilities include encouraging neurone regeneration/regrowth. They are looking at this by using certain animal species and looking at how they regenerate eg starfish.