Mendelion Genetics Flashcards
(25 cards)
Gregor Mendel (1866)
Developed inheritance by genes + alleles
Experimented with peas
Genetics
Study of inherited characteristics + how they’re transmitted between generations
Thomas Hunt Morgan
Experimented with drosophila fruit flies
Identified genes in chromosomes
Homologous chromosomes
A pair of chromosomes with similar genes
2 of each gene, 1 from each parent
Locus
Location of gene on chromosome
Alleles
Specific form of a particular gene
2 diff alleles for most genes
2 alleles in homologous pair of chromosomes, alleles can be the same or diff
Homozygous
If the pair of alleles is similar, then this allele is always expressed
Heterozygous
If the pair of alleles is different, then only one allele is expressed, the other allele is not expressed or used
Dominant allele
Expressed if heterozygous, also if homozygous
Recessive allele
Not expressed or used if heterozygous, only expressed if homozygous
Notation
Capital letter for dominant allele
Lower-case letter for recessive allele
List the dominant allele first
Genotype
The list of the 2 alleles present
Eg: AA, Aa, aa
Phenotype
The result, outcome, or physical appearance of the genotype
Punnett squares
Method to predict probabilities of offsprings
Mono hybrid cross
2X2 grid for a single gene
Cross between heterozygous
Genotype ratio = 1:2:1
Phenotype ratio = 3:1
Trihybrid cross
8X8 grid for 3 separate genes
Dihybrid cross
4X4 grid for 2 separate genes
(On 2 separate pairs of chromosomes = not linked)
Cross between heterozygous
Phenotype ratio = 9:3:3:1
P generation
Parent
True-breeding if homozygous genotype, produces uniform offsprings
F1
“Filial one” or first generation
F2
Second generation
Test cross
Experiment to reveal dominant organism
Complications
Not all genes with complete dominance (with two alleles where one is clearly dominant over the other)
Co dominance
Alleles neither dominant or recessive, heterozygote uses both alleles
Eg: sickle-cell trait (heterozygous)
Incomplete dominance
Dominant vs recessive not clear-cut, heterozygote uses dominant half-way
Eg: red X white = pink flowers