menstrualhormonesetc Flashcards

1
Q

What is GNRH

A

from hypothalamus, to anterior pituitary= ovaries LH and FSH mid cycle surge , oestrogen and progesterone

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2
Q

combined oral contraceptrive pill how does it work

A
  • progesterone: inhibits release of GNRH from hypothalamus and midcycle surge, oocytes dont develop, thickens cervical mucus
  • oestrogen: maintains endometrium, prevents problematic bleeding and inhibits and inhibits follicular development (bc produced by follicle)
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3
Q

phases of female reproductive cycle?

A
  • menstruation: FSH or LH for anterior pituitary increase , stims maturation of ovarian follicles each containing an oocyte
  • follicular: 6 days into mens cycle one follicle matures others regress, it enlarges inc oestrogen quantity produced, endometrium thickens and mucous glands grow larger, cervical mucus thinner and more alkaline which aids passage of spermatazoa through female reproductive tract
  • ovulatory: enlarging follicles produce oestrogen and it stimulates the growth of the follicle,
    mid cycle oestrogen levels increase = surge in LH secretion from anterior pituitary, follicle bursts= ovulation 32-36 hours after LH surge
  • luteal: corpus luteum forms from ruptured follicales, corp luteum produces oestrogen and progesterone and levels remain high for the next 7 days, function of progesterone to prepare body for possibility of pregnancy, one week after ovulation corpus luteum degenerates (if fertilisation absent), oestrogen and progesterone secretion decline for 12 days following ovulation at which pt corpus luteum no longer functioning, breakdown of endometrial lining, prostaglandins released from necrotic tiddue and promote flow of menstrual blood

oestrogen and progesterone concentrations decrease and FSH from ant pituitary begin a new cycle

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