Mental Health Flashcards
What is the therapeutic range for Lithium?
0.4-1.0 mmol/L
Indication of lithium
Bipolar disorder
When do the lithium levels need to be checked when dose changed?
1 week
What are the common features of PTSD?
1) Re-experiencing
2) Avoidance
3) Hyperarousal
4) emotional numbing
What ECG changes does Citalopram cause?
QT prolongation and Torsades de pointes
What are the examples of SSRI?
Citalopram
sertraline
Fluoxetine
Side effect of lorazepam
Anterograde amnesia
What should be monitored when initiating and titrating venlafaxine?
Blood pressure (HTN)
What is 2nd line option for depression?
SNRI - venlafaxine
What signs should be monitored when taking antidepressants?
Hyponatraemia
What is life-threatening side-effect of clozapine?
Agranulocystosis/Neutropenia
What is agranulocystosis?
Decreased WCC, primarily neutrophils
What is the 1st line medication for GAD?
SSRI - specifically Sertraline
What are the side effects of typical antipsychotics?
- Acute dystonia (e.g. torticollis, oculgyric crisis)
- Parkinsonism
- Akathisia (severe restlessness)
- Tardive dyskinesia
- Neuroleptic malignant syndrome
What is torticollis?
- Unilateral pain and deviation of the neck with pain on palpation and restricted range of motion
What is neuroleptic malignant syndrome?
- Altered MSE
- Generalised rigidity
- Fever
- Fluctuating blood pressure
What is tardive dyskinesia?
- uncontrolled facial movements such as lip-smacking
What are examples of typical antipsychotics?
- Haleperidol
- Chlopromazine
What are examples of atypical antipsychotics?
- Clozapine
- Risperidone
- Olanzapine
Why was atypical antipsychotics developed?
Due to problematic extrapyramidal side-effects
What is ESPEs?
- Parkinsonism
- Acute dystonia (sustained muscle contraction)
- akathisia (severe restlessness)
- tardive dyskinesia
MOA of venlafazine
Serotonin and noradrenaline reuptake inhibitor
What are the first rank symptoms of schizophrenia?
1) Auditory hallucinations
2) Thought disorder
3) Passivity phenomena
4) Delusional perceptions
For a diagnosis of PTSD, how long should symptoms be present for?
4 weeks