Mesothelioma Flashcards

1
Q

What is a mesothelioma?

A

Lung malignancy affecting the mesothelial cells of the pleural cavity

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2
Q

Where is affected by a mesothelioma?

A

The pleural cavity

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3
Q

Where else could possibly be affected by a mesothelioma?

A

Other mesothelial layers of the abdominal cavity

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4
Q

What are mesotheliomas strongly linked to?

A

Asbestos inhalation.

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5
Q

How can mesotheliomas present?

A

Dyspnoea
Weight loss
Chest wall pain
Clubbing
(Painless pleural effusion)

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6
Q

Which lung is more commonly affected by a mesothelioma?

A

Right lung more than left lung

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7
Q

How is a mesothelioma usually diagnosed?

A

Chest x-ray

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8
Q

What might you find on a chest x-ray of someone with a mesothelioma?

A

Pleural effusion or pleural thickening

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9
Q

What might you find on a chest x-ray of someone with a mesothelioma?

A

Pleural effusion or pleural thickening

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10
Q

What might you do if there is a pleural effusion present?

A

Send fluid for MC&S, biochemistry and cytology

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11
Q

What might you do after a chest x-ray in someone with a suspected mesothelioma?

A

Pleural CT

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12
Q

How long can the latent period be between asbestos exposure and mesothelioma?

A

30-40 years

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13
Q

What is the management of a mesothelioma?

A
  • Symptomatic
  • Industrial compensation
  • Chemotherapy, Surgery if operable
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14
Q

What is the prognosis for mesothelioma?

A

Poor- median survival 12 months

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15
Q

What is the use of chemotherapy in someone with mesothelioma?

A

Can improve survival but mostly palliative

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16
Q

What surgery can be carried out for someone presenting with mesothelioma?

A

Pleurectomy
Resection of lung

17
Q

What factors would indicate a poor prognosis in someone presenting with mesothelioma?

A
  • weight loss
  • increased WCC, lactate dehydrogenase and platelets
  • low Hb
    -older than 75
18
Q

What occupations risk exposure to asbestos?

A

-Mining
-Building trade
-Employment on docks, railways, or automobile industries

19
Q

How is the diagnosis of a mesothelioma made?

A

On histology following a thoracoscopy

20
Q

What is the gold standard investigation for mesothelioma to confirm the diagnosis?

A

Thoracoscopic biopsy