Metabolic Pathways: Glycogen Flashcards Preview

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Flashcards in Metabolic Pathways: Glycogen Deck (12)
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1
Q

In stage 2 of catabolism, what are the small molecules from stage 1 converted into?

A

2-carbon acetyl-CoA

some ATP is produced

2
Q

What enters the Krebs cycle where it is completely degraded to CO2 and H2O?

A

acetyl group of acetyl-CoA

3
Q

Which cell types require glucose as an energy source?

A

erythrocytes
retina
renal medulla
brain

4
Q

What is the initial pathway for the conversion of glucose to pyruvate?

A

glucose + 2 ADP + 2 Pi + 2 NAD+
»»>
2 pyruvate + 2 ATP +2 H2O + 2 NADH + 2 H+

5
Q

What does glucose turn into before eventually pyruvate?

A
  • fructose-1,6-bisphosphate

- 2 triose phosphates

6
Q

In what stage of glycolysis is glucose trapped and destabilised?

A

1

7
Q

What are the two cellular needs in glycolysis?

A

production of ATP

provision of building blocks for synthetic reactions

8
Q

What are the potential control points in glycolysis?

A

Enzymes catalysing essentially irreversible reactions

9
Q

Which enzymes are responsible for the irreversible reactions in glycolysis?

A

Hexokinase
Phosphofructokinase
Pyruvate kinase

10
Q

What is the key enzyme in the control of glycolysis?

A

Phosphofructokinase

11
Q

What are the negative modulators for phosphofructokinase?

A

ATP
citrate
H+

12
Q

What are the positive modulators for phosphofructokinase?

A

AMP

fructose 2,6-bisphosphate