METABOLISM Flashcards

(38 cards)

1
Q

Metabolism

A

All the chemical reactions that take place in the cells.

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2
Q

Catabolism

A

The process where large molecules are broken down into smaller molecules and energy.

Examples: Digestion and Deamination

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3
Q

Anabolism

A

The process when small molecules are built up into larger molecules with the use of energy.

Examples: all the synthesis

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4
Q

Nutrients

A

Nutrients are substances that can help the body in growth, repair and maintenance.

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5
Q

6 main types of nutreients

A
  1. carbohydrates
  2. proteins
  3. lipids
  4. water
  5. vitamins
  6. minerals
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6
Q

Organic nutrients/ compounds

A

Organic compounds are compounds that have a carbon chain. They include elements such as carbon, hydrogen atoms and may include, oxygen, sulfur and nitrogen.

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7
Q

Carbohydrates (Organic)

A
  • The main source of energy for cells.
  • Carbohydrates such as starch are broken down into simple sugars
  • simple sugars (glucose), are used in cellular respiration to release energy.
  • contain, hydrogen, carbon and oxygen atoms.
  • Monosaccharides - simple sugars
  • disaccharides - 2-3 simple sugars that join together to form large molecules
  • polysaccarides - many simple sugars that join together that form large carbohydrate molecules
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8
Q

Lipid (Organic)

A
  • lipids include fat and oil
  • they are also an important energy source.
  • they break down into 1-2-3 fatty acids and 1 glycerol molecule.
  • glycerol can enter cellular respiration and can be broken down to release energy.
  • other examples of lipids include phospholipids and steroids
  • the most common fat stored in our body is triglyceride.
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9
Q

Proteins (Organic)

A
  • Made up of amino acids.
  • most important proteins are enzymes.
  • proteins can be used as a source of energy BUT only if the source of carbohydrates and lipids is inadequate.
  • An amino acid consists of both an amino group and a carboxylic group.
  • When 2 amino acids combine, these 2 groups form a peptide bond, releasing a water molecule.

dipeptides - shorter lengths of amino acids with 2 amino acids joined

  • polypeptides - 10 amino acids.

ALWAYS CONTAIN O, H, Ca, N, S , F

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10
Q

Inorganic compounds

A

Compounds that are not based on a carbon chain.

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11
Q

Water (Inorganic)

A

Water is an important organic substance as it is the fluid that other substances are dissolved in.

some chemical reactions occur in water.

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12
Q

Minerals (Inorganic)

A

Minerals are important because they may be apart of enzymes.

May act like a co-factor for enzymes.

May be apart of ATP that are involved in metabolism

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13
Q

Vitamins (Inogranic)

A

Act as co-enzymes for the many chemical reactions.

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14
Q

Conditions met for chemical reactions to occur.

A

They need a sufficient amount of activation energy

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15
Q

Activation energy

A

The reacting particles need to collide with enough energy to break the bonds.

Particles must also collide so that the correct atoms come into contact with one another.

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16
Q

Temperature and activation energy

A

At any give temperature, a certain proportion of particles will have enough energy to satisfy the activation energy.

The proportion will increase, as the temperature increases.

17
Q

Catalysts

A

Chemicals that lower the activation energy, and increase the rate of reactions. They are not consumed in the reaction making them more effective.

Catalysts are proteins called enzymes.

without enzymes, the reactions would be too slow

18
Q

Substrate

A

The molecules on which an enzyme acts in.

19
Q

Active site

A

The part of an enzyme molecule that combines with the substrate is called the active site.

20
Q

Enzyme substrate complex

A

Occurs when an enzyme and substrate combines.

There are 2 models:
1. The lock and key model
2. Induced fit model

21
Q

The lock and key model

A

The shape of the enzyme is always complementary to the shape of the substrate.

22
Q

The induced fit model

A

When the enzyme and substrate join, they form weak bonds that cause the shape of the enzyme to change, creating complementary shapes.

23
Q

Factors affecting enzymes activity

A
  1. The higher concentration of enzymes
  2. Increase substrace concentration also increases the rate of the reaction.
  3. The product of the reaction must be continually removed
  4. the temperature influences enzyme activity
  5. enzymes are very sensitive to the PH of the medium in which a reaction is taking place.
24
Q

Co-factors

A

Ions and non-proteins that are present before enzymes catalyse a reaction.

they can also change the shape of the active site.

without a cofactor enzymes cannot function

25
Co- enzymes
some co-factors that are organic molecules. Many vitamins
26
Enzyme inhibitors
Substances that slow or even stop the enzyme's activity. Many drugs are an example
27
Cellular respiration
The process of which cells break down organic molecules to produce energy in the form of ATP for the cells activities. Most important metabolic processes in any cell can release energy from, glucose, amino acids, fatty acids, and glycerol
28
Cells activities
- Movement of the cell - Movement of material across the cell membrane - uptake of material from surrounding - production and secretion of chemicals
29
Cellular respiration equation
glucose + oxygen = carbon-dioxide+ water + energy (ATP and heat)
30
Energy from Cellular respiration (HEAT)
- In the complete breakdown of glucose, about 60% of the available energy is released as heat. - Heat is important to keep body temperatures constant as they are continually lost to the environment.
31
Energy from Cellular respiration (ATP)
- The remaining energy (40%) is used to form a compound called adenosine triphosphate (ATP) - adenosine - which is make up of the nucleic acid bases adenine and the ribose sugar. - thee phosphate groups. - ATP is formed when an inorganic phosphate group is attached to ADP. - Some energy is form cellular respiration is stored in here. - This bond can easily be broken, allowing energy to be released when needed. - As energy is released (can be re-used) ADP is formed gain.
32
Glycolysis
The first phase in breaking down glucose to 2 pyruvate molecules, doesn't require oxygen.
33
Anaerobic respiration
- Respiration with the lack of oxygen. - The process of glycolysis and conversion of pyruvate to lactic acid is available in the cytosol. - one molecule of glucose is enough to convert 2 molecules from ADP to ATP, with the absence of oxygen. - Anaerobic respiration is very important for vigorous activity, when the respiratory and circulatory systems are unable to supply muscle cells with enough oxygen to meet all the energy demands for the contracting muscles.
34
Lactic acid in anaerobic respiration
- lactic acids may cause muscle pain, due to anaerobic respiration producing extra energy. - lactic acids are taken by the blood to the liver, where it can recombine with oxygen to form glucose and eventually glycogen. - this process needs oxygen.
35
Oxygen debt
After running, runners breathe heavily for some time because the oxygen debt must be repaid by converting lactic acid into glucose.
36
Recovery oxygen
The extra oxygen required after exercise.
37
Aerobic respiration
- Respiration requiring oxygen -complete breakdown of glucose to carbon-dioxide and water, requires oxygen. - Process occurs in the inner membrane of the mitochondria, the folds of the internal membrane provides a large surface area in which these reactions can take place.
38
aerobic respiration steps
1. For pyruvate to enter the mitochondria, carbon-dioxide is removed from the pyruvate and it forms acetyl co-enzyme A. (NO ATP PRODUCED) 2. The acetyl COA, enters the citric acid cycle (Krebs cycle). Here the carbon atoms in the acetyl COA are released in carbon-dioxide. For every acetyl COA that enters the cycle, one molecule of ATP is also produced. This means that 2 ATP molecules are produced per glucose molecule. 3. The final step is known as the electron transport chain, the only stage that uses oxygen. here the electrons are passes between molecules, finally resulting in oxygen molecules forming water. roughly around 26034 molecules are produced during this process.