metabolism

Question 1

what are the 2 phases of glycolysis?

Answer 1

initial phase (6C to 2x3C) and second phase (3C to pyruvate)

Question 2

if oxygen is present, what happens to pyruvate?

Answer 2

enters the mitochondrion for the krebs cycle and electron transport chain

Question 3

if oxygen is low, what happens to pyruvate?

Answer 3

turned into lactic acid

Question 4

what is the cori cycle?

Answer 4

lactate goes through the blood into the liver and gets metabolised to pyruvate and then to glucose

Question 5

what is gluconeogenesis?

Answer 5

reverse of glycolysis

Question 6

how is glycolysis regulated?

Answer 6

activation and inhibition of enzymes

Question 7

what is the link reaction?

Answer 7

pyruvate is transported into mitochondria by attaching to a CoA molecule

Question 8

what is the krebs cycle?

Answer 8

happens in the mitochondria

Question 9

what is krebs cycle regulated by?

Answer 9

enzyme inhibited by ATP, acetyl CoA

Question 10

what is the sequence of events in metabolism?

Answer 10

b-oxidation of fatty acids or glycolysis -> link reaction -> krebs cycle -> oxidative phosphorylation

Question 11

what is the total ATP yield from 1 glucose?

Answer 11

32 ATP

Question 12

what can interfere with oxidative phosphorylation?

Answer 12

uncouplers (mitochondrial membrane becomes leaky and proton gradient collapses)
inhibitors (bind to components of ETC and block electron transfer)