metabolism Flashcards
(28 cards)
what is hypoglycaemia?
an inadequate supply of glucose to the brain
What are the negative effects of hypoglycaemia?
Effects can range from mild dysphoria, seizures, unconsciousness, permanent brain damage or death;
What is Hyperglycemia
Excessively high blood glucose
What are the negative effects of hyperglycaemia?
leads to cell dehydration. can cause cataract in the eyes.
Does Glycogen affect osmotic pressure?
NO!
where is glycogen found?
Glial cells and Liver
What is gluconeogenesis?
The production of glucose from a non sugar source.
glycogenolysis
breakdown of glycogen to produce glucose
Muscle glycogen is used for what?
internal use. (muscles)
Fatty acids cannot be made into glycogen, but what can?
glycerol. backbone of fatty acid
What does the adrenal medulla secrete
epinephrine
what does the adrenal cortex secrete?
glucocorticoids cortisol/corticosterone
What does the pituitary secrete?
GH
What does the thyroid gland secrete?
• T3 &T4
In the pancreas there is Islets of Langerhans are scattered in great numbers throughout. What doe the alpha and beta cells release>
alpha cells-glucagon
beta-insulin
when is insulin released?
when blood glucose is high
When is glucagon released?
when blood glucose is low
What are acute side effects of prolonged high blood sugar
High blood sugar include frequent urination, increased thirst, and increased hunger;
– Acute complications include diabetic ketoacidosis and nonketotic hyperosmolar coma;
What are severe side effects of prolonged high blood sugar(diabetes mellitus)
Long-term complications include cardiovascular disease, stroke, chronic kidney failure, foot ulcers, and damage to the eyes
What are the 3 types of diabetes?
Type 1 - pancreas fail to produce enough insulin;
Type 2 - insulin resistance;
– Cells fail to respond to insulin;
Gestational diabetes - pregnant women without a previous history of diabetes develop a high blood-sugar level.
Diabetes is disease of the ______ system in which _____ is deficient or cells become resistant to it.
endocrine, insulin
When insulin is released what does it increase?
- production of glycogen
- lipid synthesis
- esterfication of fatty acids
- amino acid uptake
When insulin is released what does it decrease>
- proteolysis
- lypolysis
- gluconeogensis
Cholesterol is a presursor for what 6 other hormones?
- estradiol
- cortisol
- aldesterone
- testosterone
- progesterone
- pregegonal