METABOLISM AND ENDOCRINE SYSTEM Flashcards
(94 cards)
is a term that describes the biochemical processes that allow people to grow, reproduce, repair damage, and respond to their environment.
Metabolism
A broad category of diseases that can be caused by enzyme deficiencies, genetic defects, or organ dysfunction.
Metabolic disorder
A type of metabolic disorder that affects organs, tissues, or cells.Examples include type 2 diabetes, non-alcoholic fatty liver disease, and obesity.
Metabolic diseases
Also known as inborn errors of metabolism, these disorders are caused by a defective gene that leads to an enzyme deficiency.
Inherited metabolic disorders
Metabolic diseases can occur when the liver or pancreas aren’t functioning properly.
Organ dysfunction
The severity of a metabolic disease is usually determined by the level of destruction of the abnormal enzyme. t or f
f; level of function
plays a central role in metabolism, acting as the body’s primary organ for processing nutrients, regulating blood glucose levels, synthesizing essential molecules like proteins and lipids, and detoxifying harmful substances, making it a critical player in maintaining overall metabolic homeostasis
liver
is the “hub” of metabolism, constantly adapting its functions based on the body’s nutritional state, whether in a fed or fasted state.
liver
The pancreas synthesizes lipoproteins like very low-density lipoprotein (VLDL) which transport triglycerides to other tissues for energy storage, and also breaks down fatty acids for energy production.
t or f
f; liver
significantly influence the liver’s metabolic activity, dictating whether it stores or releases nutrients depending on the body’s needs.
Hormones
Breakdown of glucose for energy production.
Glycolysis
Storage of glucose as glycogen
Glycogenesis
Breakdown of glycogen to release glucose
Glycogenolysis
Synthesis of new glucose from non-carbohydrate sources like amino acids
Gluconeogenesis
Synthesis of fatty acids from carbohydrates
Lipogenesis
Breakdown of fatty acids for energy
Beta-oxidation
Detoxification of ammonia produced from protein metabolism
Urea cycle
Inability to maintain blood glucose levels due to impaired gluconeogenesis
Hypoglycemia
Elevated levels of cholesterol and triglycerides in the blood due to abnormal lipid metabolism
Hyperlipidemia
Reduced protein synthesis impacting various bodily functions
Protein deficiency
Inability to effectively detoxify harmful substances
Accumulation of toxins
Produced by the pancreas, lowers blood sugar levels by promoting glucose uptake into cells.
Insulin
Also from the pancreas, raises blood sugar levels by stimulating the breakdown of glycogen stores in the liver.
Glucagon
Secreted by the thyroid gland, control the body’s overall metabolic rate, impacting energy expenditure and body temperature.
Thyroid hormones