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ZOTC 60 Metabolism Exam > Metabolism and TCA/Krebs/CAC > Flashcards

Metabolism and TCA/Krebs/CAC Flashcards

1
Q

– A central theme in biochemistry which keeps the cells & organisms alive
– It gives the energy to carry on & the building blocks required for growth & multiplication

A

Metabolism

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2
Q

degradative – turning down

A

Catabolic

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3
Q

synthetic – synthesis

A

Anabolic

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4
Q

Central hub (para magamit for energy)

A

Kreb’s cycle (citric acid cycle)

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5
Q

Ultimate product of nutrient metabolism

A

ATP

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6
Q

means splitting

A

Lysis

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7
Q

means building up

A

Genesis

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8
Q

break down of proteins

A

Proteolysis

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9
Q

break down of carbohydrates

A

Glycolysis

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10
Q

Glucose starting point

A

Glucogenesis

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11
Q

Non glucose sources

A

Gluconeogenesis

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12
Q

degrading of fats

A

lipolysis

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13
Q

building up of fats

A

lipogenesis

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14
Q

Reducing powers (catabolic reaction) and how many ATP would it produce

A

NADH (nicotinamide adenine dinucleotide + hydrogen) (3 ATPs)
FADH2 (flavin adenine dinucleotide + H) (2 ATPs)

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15
Q

synthesis of small molecules

A

Anabolic metabolism

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16
Q

Catabolic reactions: (3)

A

Production of ATP
Production of reducing power (NADH)
Regeneration of building blocks for anabolic metabolism

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17
Q

Anabolic reactions: (2)

A

Synthesis of small molecules & building blocks that aren’t sufficiently avail in food
Synthesis of macromolecules (proteins & nuclei acids)

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18
Q

Glucose to 2 pyruvate or pyruvic acid

A

glycolysis

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19
Q

pyruvic acid to glucose

A

gluconeogenesis

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20
Q

glucose to glycogen

A

glycogenesis

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21
Q

glycogen to glucose

A

glycogenolysis

22
Q

Triacylglycerol to fatty acid + glycerol

A

Lipolysis

23
Q

fatty acid + glycerol to TAGs

A

lipogenesis

24
Q

storage form of glucose

A

glycogen

25
Q

storage form of fats

A

triglyceride

26
Q

Product of glycolysis

A

2 Pyruvate

27
Q

6 carbon molecule

A

Glucose

28
Q

reduction is gaining

A

RIG

29
Q

oxidation is losing

A

OIL

30
Q

what part of the cell does glycolysis happen

A

Cytoplasm

31
Q

what part of the cell does kreb’s cycle,CAC happen

A

Mitochondria and matrix
parts:
cristae, outer, inner, intermembrane

32
Q

which part of the cel does ETC happen

A

mitcohondria

33
Q

1 mol of glucose produces how many mol of pyruvate

A

2

34
Q

TCA Cycle/Krebs/CAC
1 pyruvate mol will be converted to _____ Aerobic cycle (prep stage)

A

Acetyl-CoA

35
Q

In conversion of pyruvate to Acetyl-CoA, what enzyme and reducing powers are involved? (prep stage)

A

Enzyme: pyruvate dehydrogenase
2NAD+ is converted to 2NADH +CO2

36
Q

in 1st step CAC, acetyl coA will react with ____ to be converted to _____. what enzyme is involved?

A

oxaloacetate
citrate
citrate synthase

37
Q

in CAC 2nd step, from citrate it will be converted to ____ (cis-aconitase). what enzyme is involved?

A

D- isocitrate
aconitase

38
Q

3rd step d-isocitrate will be converted to _____. what reducing powers and enzyme are involved?

A

alpha-ketoglutarate
isocitrate dehydrogenase
2NAD&raquo_space;> 2NADH +CO2

39
Q

4th step alpha ketoglutarate will be converted to ____. what enzyme and reducing powers are invloved?

A

Succinyl CoA
alpha ketoglutarate dehydrogenase
2NAD&raquo_space;> 2NADH + CO2

40
Q

5th from succinyl coa, it will be converted to ____. what enzyme is involved? in this case how many ATP will be produced and by what?

A

Succinate
succinyl CoA synthase
1 ATP is produced by GTP

41
Q

6th succinate»> ___. enzyme involved? QH2 will be converted to ___. how many cycles?

A

fumrate
sucunate dehydrogenase
FADH2 x 2(cycles)

42
Q

7th fumrate&raquo_space;> ___. enzyme involved?

A

malate
fumrase

43
Q

8th malate»>____. enzyme involved? Reducing powers involved?

A

oxaloacetate
malate dehydrogenase
NAD»>2NADH

44
Q

net reaction of krebs/TCA/CAC

A

3 NADH = 6
1 FADH = 2
1 GTP = 2
2 CO2 = 4
since 2 cycles ito

45
Q

Ultimate electron acceptor

A

Oxygen

46
Q

what decreases if you do fasting

A

glucagon

47
Q

tumataas ang ___ after kumain

A

insulin

48
Q

% energy metabolism, protein

A

10-15%

49
Q

where does products of aa land

A

liver

50
Q

aa fate in liver (3)

A

glycogen, protein synthesis, glucose/FA

51
Q

what do you call the conversion of acetyl coA → FA → for energy? what aa are involved

A

Ketogenic
lysine & leucine

52
Q

amino acids convertible to glucose

A

Glucogenic

ZOTC 60 Metabolism Exam (2 decks)

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